Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C6H8O8 |
| Molecular Weight | 208.1229 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O[C@H](C(O)=O)[C@@](O)(CC(O)=O)C(O)=O
InChI
InChIKey=ZMJBYMUCKBYSCP-CVYQJGLWSA-N
InChI=1S/C6H8O8/c7-2(8)1-6(14,5(12)13)3(9)4(10)11/h3,9,14H,1H2,(H,7,8)(H,10,11)(H,12,13)/t3-,6+/m1/s1
| Molecular Formula | C6H8O8 |
| Molecular Weight | 208.1229 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Screening of well-established drugs targeting cancer metabolism: reproducibility of the efficacy of a highly effective drug combination in mice. | 2012-08 |
|
| Safety assessment of a calcium-potassium salt of (-)-hydroxycitric acid. | 2010-11 |
|
| Meta-analysis for the effect of medical therapy vs. placebo on recovery of idiopathic sudden hearing loss. | 2010-09 |
|
| Both common and specialty mushrooms inhibit adhesion molecule expression and in vitro binding of monocytes to human aortic endothelial cells in a pro-inflammatory environment. | 2010-07-16 |
|
| Aqueous extract of garcinia indica choisy restores glutathione in type 2 diabetic rats. | 2010-07 |
|
| Maitake mushroom extracts ameliorate progressive hypertension and other chronic metabolic perturbations in aging female rats. | 2010-06-07 |
|
| Identification of ATP citrate lyase as a positive regulator of glycolytic function in glioblastomas. | 2010-05-15 |
|
| A combination of alpha lipoic acid and calcium hydroxycitrate is efficient against mouse cancer models: preliminary results. | 2010-05 |
|
| Glycation of aspartate aminotransferase by methylglyoxal, effect of hydroxycitric and uric acid. | 2009-11 |
|
| Direct characterization of aqueous extract of Hibiscus sabdariffa using HPLC with diode array detection coupled to ESI and ion trap MS. | 2009-10 |
|
| Emerging role of Garcinol, the antioxidant chalcone from Garcinia indica Choisy and its synthetic analogs. | 2009-09-02 |
|
| No evidence demonstrating hepatotoxicity associated with hydroxycitric acid. | 2009-08-28 |
|
| Missing data in randomized clinical trials for weight loss: scope of the problem, state of the field, and performance of statistical methods. | 2009-08-13 |
|
| Acute effects of pharmacological modifications of fatty acid metabolism on human satiety. | 2009-06 |
|
| A change-point regression approach for efficacy evaluation of dietary supplements. | 2009-05 |
|
| Effects of Garcinia atroviridis on serum profiles and atherosclerotic lesions in the aorta of guinea pigs fed a high cholesterol diet. | 2009-03 |
|
| Effect of Hibiscus sabdariffa L. dried calyx ethanol extract on fat absorption-excretion, and body weight implication in rats. | 2009 |
|
| Body circumferences: clinical implications emerging from a new geometric model. | 2008-10-06 |
|
| Nutrigenomic analysis of diet-gene interactions on functional supplements for weight management. | 2008-06 |
|
| Interaction of Aqueous Extract of Pleurotus pulmonarius (Fr.) Quel-Champ. with Glyburide in Alloxan Induced Diabetic Mice. | 2008-06 |
|
| Effects of Garcinia cambogia extract on serum sex hormones in overweight subjects. | 2008-06 |
|
| Effects on the Human Body of a Dietary Supplement Containing L-Carnitine and Garcinia cambogia Extract: A Study using Double-blind Tests. | 2008-03 |
|
| Capillary zone electrophoresis for separation and analysis of hydroxycitric acid and hydroxycitric acid lactone: application to herbal products of Garcinia atroviridis Griff. | 2008-02-13 |
|
| Safety of a Novel Calcium/Potassium Saltof (-)-Hydroxycitric Acid (HCA-SX): II.Developmental Toxicity Study in Rats. | 2008 |
|
| Safety of a Novel Calcium/Potassium Salt of Hydroxycitric Acid (HCA-SX): I. Two-Generation Reproduction Toxicity Study. | 2008 |
|
| Beta-glucans in the treatment of diabetes and associated cardiovascular risks. | 2008 |
|
| Refuting "Evaluation of the genotoxitocity of (-)-hydroxycitric acid (HCA-SX) isolated from Garcinia Cambogia" by Lee and Lee, Journal of Toxicology and Environmental Health, 70:388-392, 2007. | 2008 |
|
| Effects of ingesting JavaFit Energy Extreme functional coffee on aerobic and anaerobic fitness markers in recreationally-active coffee consumers. | 2007-12-08 |
|
| Efficacy of Slim339 in reducing body weight of overweight and obese human subjects. | 2007-12 |
|
| Effects of Citric Acid and l-Carnitine on Physical Fatigue. | 2007-11 |
|
| Acute effects of ingesting Java Fittrade mark energy extreme functional coffee on resting energy expenditure and hemodynamic responses in male and female coffee drinkers. | 2007-10-05 |
|
| Super CitriMax (HCA-SX) attenuates increases in oxidative stress, inflammation, insulin resistance, and body weight in developing obese Zucker rats. | 2007-10 |
|
| Hibiscus sabdariffa affects ammonium chloride-induced hyperammonemic rats. | 2007-09 |
|
| Transcriptome of primary adipocytes from obese women in response to a novel hydroxycitric acid-based dietary supplement. | 2007-09 |
|
| Chemistry, physiological properties, and microbial production of hydroxycitric acid. | 2007-07 |
|
| Therapeutic efficacy and safety of undenatured type-II collagen (UC-II) alone or in combination with (-)-hydroxycitric acid and chromemate in arthritic dogs. | 2007-06 |
|
| Evaluation of the genotoxicity of (-)-hydroxycitric acid (HCA-SX) isolated from Garcinia cambogia. | 2007-03-01 |
|
| Genome shuffling of Streptomyces sp. U121 for improved production of hydroxycitric acid. | 2007-01 |
|
| Exploiting hypoxia in solid tumors to achieve oncolysis. | 2007 |
|
| Beneficial and deleterious effects of hydroxycitrate in rats fed a high-fructose diet. | 2006-09 |
|
| Absolute configuration of hydroxycitric acid produced by microorganisms. | 2006-08 |
|
| Effects of (-)-hydroxycitrate on net fat synthesis as de novo lipogenesis. | 2006-07-30 |
|
| Comparison of the effects of three different (-)-hydroxycitric acid preparations on food intake in rats: response. | 2006-07-17 |
|
| Thermogenic effect from nutritionally enriched coffee consumption. | 2006-06-05 |
|
| [In vitro chromosome aberration test and in vivo micronucleus test of Ca-type Garcinia extract]. | 2006-04 |
|
| Effect of food deprivation and hormones of glucose homeostasis on the acetyl CoA carboxylase activity in mouse brain: a potential role of acc in the regulation of energy balance. | 2006-02-16 |
|
| DNA microarray technology in the evaluation of weight management potential of a novel calcium-potassium salt of (-)-hydroxycitric Acid. | 2006 |
|
| Comparison of the effects of three different (-)-hydroxycitric acid preparations on food intake in rats. | 2005-09-13 |
|
| Production of hydroxycitric acid by microorganisms. | 2005-08 |
|
| Efficacy of a novel calcium/potassium salt of (-)-hydroxycitric acid in weight control. | 2005 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:45:05 GMT 2025
by
admin
on
Mon Mar 31 18:45:05 GMT 2025
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| Record UNII |
8W94T9026R
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| Record Status |
Validated (UNII)
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| Record Version |
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-
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Preferred Name | English | ||
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Systematic Name | English | ||
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Common Name | English | ||
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| Classification Tree | Code System | Code | ||
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DSLD |
2324 (Number of products:70)
Created by
admin on Mon Mar 31 18:45:05 GMT 2025 , Edited by admin on Mon Mar 31 18:45:05 GMT 2025
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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C007999
Created by
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PRIMARY | |||
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HYDROXYCITRIC ACID
Created by
admin on Mon Mar 31 18:45:05 GMT 2025 , Edited by admin on Mon Mar 31 18:45:05 GMT 2025
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PRIMARY | |||
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185620
Created by
admin on Mon Mar 31 18:45:05 GMT 2025 , Edited by admin on Mon Mar 31 18:45:05 GMT 2025
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PRIMARY | |||
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1312602
Created by
admin on Mon Mar 31 18:45:05 GMT 2025 , Edited by admin on Mon Mar 31 18:45:05 GMT 2025
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PRIMARY | RxNorm | ||
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m6131
Created by
admin on Mon Mar 31 18:45:05 GMT 2025 , Edited by admin on Mon Mar 31 18:45:05 GMT 2025
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PRIMARY | Merck Index | ||
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100000125898
Created by
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PRIMARY | |||
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SUB33094
Created by
admin on Mon Mar 31 18:45:05 GMT 2025 , Edited by admin on Mon Mar 31 18:45:05 GMT 2025
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PRIMARY | |||
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8W94T9026R
Created by
admin on Mon Mar 31 18:45:05 GMT 2025 , Edited by admin on Mon Mar 31 18:45:05 GMT 2025
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PRIMARY | |||
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8W94T9026R
Created by
admin on Mon Mar 31 18:45:05 GMT 2025 , Edited by admin on Mon Mar 31 18:45:05 GMT 2025
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PRIMARY | |||
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6205-14-7
Created by
admin on Mon Mar 31 18:45:05 GMT 2025 , Edited by admin on Mon Mar 31 18:45:05 GMT 2025
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NON-SPECIFIC STEREOCHEMISTRY | |||
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27750-10-3
Created by
admin on Mon Mar 31 18:45:05 GMT 2025 , Edited by admin on Mon Mar 31 18:45:05 GMT 2025
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PRIMARY | |||
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DTXSID601045116
Created by
admin on Mon Mar 31 18:45:05 GMT 2025 , Edited by admin on Mon Mar 31 18:45:05 GMT 2025
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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TARGET -> INHIBITOR |
Ki
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SALT/SOLVATE -> PARENT | |||
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PARENT -> CONSTITUENT ALWAYS PRESENT |
| Related Record | Type | Details | ||
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ACTIVE MOIETY |
