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Details

Stereochemistry ACHIRAL
Molecular Formula C3H5N3O.ClH
Molecular Weight 135.552
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CYACETACIDE HYDROCHLORIDE

SMILES

Cl.NNC(=O)CC#N

InChI

InChIKey=CEOVDOULQCPTMU-UHFFFAOYSA-N
InChI=1S/C3H5N3O.ClH/c4-2-1-3(7)6-5;/h1,5H2,(H,6,7);1H

HIDE SMILES / InChI
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C3H5N3O
Molecular Weight 99.0913
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Cyacetacide is a biochemical used in the past as an anti-tuberculosis agent and currently used in Russia to for the treatment of various forms of tubercular lesions of the eye: keratitis, scleritis, uveitis, chorioretinitis, tuberculosis-allergic diseases and eye diseases of non-tubercular origin. Cyacetacide has also been used to derive compounds that may have antitumor properties.

Originator

Approval Year

Unknown
139594
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
Withdrawn
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
The reaction of cyanoacetylhydrazine with omega-bromo(4-methyl)acetophenone: synthesis of heterocyclic derivatives with antitumor activity.
2010 May 17
Patents

Patents

04545810
2
07666647
2

Sample Use Guides

In Vivo Use Guide
Ciazide is administered orally 0.1 g 3 times a day for a month (total 9.0 g of the drug), and then in combination with other antibacterial drugs.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:53:12 GMT 2023
Edited
by admin
on Sat Dec 16 08:53:12 GMT 2023
Record UNII
8W5485PW3E
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CYACETACIDE HYDROCHLORIDE
MI  
Common Name English
CYANOACETIC ACID HYDRAZIDE HYDROCHLORIDE
Systematic Name English
ACETIC ACID, 2-CYANO-, HYDRAZIDE, HYDROCHLORIDE (1:1)
Systematic Name English
CYANOACETHYDRAZIDE MONOHYDROCHLORIDE
Systematic Name English
CYACETACIDE HYDROCHLORIDE [MI]
Common Name English
Code System Code Type Description
PUBCHEM
12235876
Created by admin on Sat Dec 16 08:53:12 GMT 2023 , Edited by admin on Sat Dec 16 08:53:12 GMT 2023
PRIMARY
CAS
5897-13-2
Created by admin on Sat Dec 16 08:53:12 GMT 2023 , Edited by admin on Sat Dec 16 08:53:12 GMT 2023
PRIMARY
MERCK INDEX
m3940
Created by admin on Sat Dec 16 08:53:12 GMT 2023 , Edited by admin on Sat Dec 16 08:53:12 GMT 2023
PRIMARY Merck Index
FDA UNII
8W5485PW3E
Created by admin on Sat Dec 16 08:53:12 GMT 2023 , Edited by admin on Sat Dec 16 08:53:12 GMT 2023
PRIMARY
NIH
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