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Details

Stereochemistry ACHIRAL
Molecular Formula C2F6O5S2
Molecular Weight 282.139
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Trifluoromethanesulfonic anhydride

SMILES

FC(F)(F)S(=O)(=O)OS(=O)(=O)C(F)(F)F

InChI

InChIKey=WJKHJLXJJJATHN-UHFFFAOYSA-N
InChI=1S/C2F6O5S2/c3-1(4,5)14(9,10)13-15(11,12)2(6,7)8

HIDE SMILES / InChI

Molecular Formula C2F6O5S2
Molecular Weight 282.139
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
A straightforward approach towards 5-substituted thiazolylpeptides via the thio-Ugi-reaction.
2010-12-07
Aminopyrazine inhibitors binding to an unusual inactive conformation of the mitotic kinase Nek2: SAR and structural characterization.
2010-11-11
Stereoselective synthesis of 2,3,6-trisubstituted tetrahydropyridines via Tf(2)O-mediated Grob fragmentation: access to indolizidines (-)-209I and (-)-223J.
2010-11-05
Controlled and chemoselective reduction of secondary amides.
2010-09-22
Difluorobenzocyclooctyne: synthesis, reactivity, and stabilization by beta-cyclodextrin.
2010-08-25
Synthesis and reactivity of rhodium(II) N-triflyl azavinyl carbenes.
2010-03-03
2-Azido-3,4;6,7-di-O-isopropyl-idene-α-d-glycero-d-talo-heptopyran-ose.
2010-02-06
N-(4-Chloro-phen-yl)-1,1,1-trifluoro-N-(trifluoro-methyl-sulfon-yl)methane-sulfonamide.
2010-02-03
Calyculins and related marine natural products as serine-threonine protein phosphatase PP1 and PP2A inhibitors and total syntheses of calyculin A, B, and C.
2010-01-21
Highly stereoselective synthesis of alpha-D-mannopyranosyl phosphosugars.
2009-12-18
PIKfyve regulation of endosome-linked pathways.
2009-07
Nucleophilic reactivity of a d0 molybdenum oxo moiety.
2009-02-21
Efficient dehydrative sialylation of C-4-aminated sialyl-hemiketal donors with Ph2SO/Tf2O.
2009-02-20
Pre-activation of fully acetylated dodecyl thioglycosides with BSP-Tf2O led to efficient glycosylation at low temperature.
2009-02-17
Direct dehydrative N-pyridinylation of amides.
2009-02-06
Stereocontrolled synthesis of D- and L-beta-rhamnopyranosides with 4-O-6-S-alpha-cyanobenzylidene-protected 6-thiorhamnopyranosyl thioglycosides.
2009-01-16
Is donor-acceptor hydrogen bonding necessary for 4,6-O-benzylidene-directed beta-mannopyranosylation? Stereoselective synthesis of beta-C-mannopyranosides and alpha-C-glucopyranosides.
2008-11-06
Selective mono reduction of bis-phosphine oxides under mild conditions.
2008-10-07
A versatile and highly stereoselective access to vinyl triflates derived from 1,3-dicarbonyl and related compounds.
2008-10-03
A versatile cyclodehydration reaction for the synthesis of isoquinoline and beta-carboline derivatives.
2008-08-21
Electrophile-induced dearomatizing spirocyclization of N-arylisonicotinamides: a route to spirocyclic piperidines.
2008-07-17
Stereoselective synthesis of acetoacetate-derived enol triflates.
2008-07-03
Stereoselective direct glycosylation with anomeric hydroxy sugars by activation with phthalic anhydride and trifluoromethanesulfonic anhydride involving glycosyl phthalate intermediates.
2008-07-02
The structure of polymer-supported triphenylphosphine ditriflate: a potentially useful reagent in organic synthesis.
2008-06-20
Total synthesis of siomycin A: construction of synthetic segments.
2008-06-02
Highly chemoselective metal-free reduction of tertiary amides.
2008-01-09
Overall "pseudocationic" trifluoromethylation of dihydropyridines with triflic anhydride.
2008
Synthesis of benzo[b]thiophenes by cyclization of arylketene dithioacetal monoxides under pummerer-like conditions.
2007-12-20
Bis(nona-fluoro-butane-sulfonato-κO)dioxidotris(tetra-hydro-furan-κO)uranium(VI).
2007-12-12
Synthesis of densely functionalized enantiopure indolizidines by ring-closing metathesis (RCM) of hydroxylamines from carbohydrate-derived nitrones.
2007-12-12
A new, powerful glycosylation method: activation of thioglycosides with dimethyl disulfide-triflic anhydride.
2007-10-25
Synthesis and glycosylation of a series of 6-mono-, di-, and trifluoro S-phenyl 2,3,4-tri-O-benzyl-thiorhamnopyranosides. Effect of the fluorine substituents on glycosylation stereoselectivity.
2007-09-26
Fragmentation of nitrone triflates to 9-membered rings.
2007-08-16
Studies on the intramolecular cyclizations of bicyclic delta-hydroxynitriles promoted by triflic anhydride.
2007-05-11
On the use of 3,5-O-benzylidene and 3,5-O-(di-tert-butylsilylene)-2-O-benzylarabinothiofuranosides and their sulfoxides as glycosyl donors for the synthesis of beta-arabinofuranosides: importance of the activation method.
2007-03-02
4,6-O-benzylidene-directed beta-mannopyranosylation and alpha-glucopyranosylation: the 2-deoxy-2-fluoro and 3-deoxy-3-fluoro series of donors and the importance of the O2-C2-C3-O3 interaction.
2007-03-02
Synthesis of pyrimidines by direct condensation of amides and nitriles.
2007
Preparation of the functionalizable methionine surrogate azidohomoalanine via copper-catalyzed diazo transfer.
2007
Synthesis of a pentasaccharide fragment of varianose, a cell wall polysaccharide from Penicillium varians.
2006-12-22
Single-step synthesis of pyrimidine derivatives.
2006-11-08
On the influence of the C2-O2 and C3-O3 bonds in 4,6-O-benzylidene-directed beta-mannopyranosylation and alpha-glucopyranosylation.
2006-10-27
Synthesis of L-daunosamine and L-ristosamine glycosides via photoinduced aziridination. Conversion to thioglycosides for use in glycosylation reactions.
2006-10-13
Barbituric acid as a substituent at aryl methylium ions.
2006-09-29
Chromene chromium carbene complexes in the syntheses of naphthopyran and naphthopyrandione units present in photochromic materials and biologically active natural products.
2006-08-30
Synthesis and cross-coupling reactions of 7-azaindoles via a new donor-acceptor cyclopropane.
2006-08-17
On the nitrile effect in L-rhamnopyranosylation.
2006-07-24
Synthesis of n-octyl 2,6-dideoxy-alpha-L-lyxo-hexopyranosyl-(1-->2)-3-amino-3-deoxy-beta-D-galactopyranoside, an analog of the H-disaccharide antigen.
2006-07-24
Stereoselective synthesis of Z-alpha-aryl-alpha,beta-unsaturated esters.
2006-06-23
Stereocontrolled synthesis of the D- and L-glycero-beta-D-manno-heptopyranosides and their 6-deoxy analogues. Synthesis of methyl alpha-l-rhamno-pyranosyl-(1-->3)-D-glycero-beta-D-manno-heptopyranosyl- (1-->3)-6-deoxy-glycero-beta-D-manno-heptopyranosyl-(1-->4)-alpha-L- rhamno-pyranoside, a tetrasaccharide subunit of the lipopolysaccharide from Plesimonas shigelloides.
2006-06-21
New easy approach to the synthesis of 2,5-disubstituted and 2,4,5-trisubstituted 1,3-oxazoles. The reaction of 1-(methylthio)acetone with nitriles.
2006-04-14
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 23:34:15 GMT 2025
Edited
by admin
on Mon Mar 31 23:34:15 GMT 2025
Record UNII
8W034LHG1U
Record Status Validated (UNII)
Record Version
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Name Type Language
Trifluoromethanesulfonic anhydride
MI  
Systematic Name English
Triflate anhydride
Preferred Name English
Triflic anhydride
Systematic Name English
Trifluoromethanesulfonic anyhydride [MI]
Common Name English
Triflic acid anhydride
Systematic Name English
Methanesulfonic acid, 1,1,1-trifluoro-, 1,1?-anhydride
Systematic Name English
Code System Code Type Description
FDA UNII
8W034LHG1U
Created by admin on Mon Mar 31 23:34:15 GMT 2025 , Edited by admin on Mon Mar 31 23:34:15 GMT 2025
PRIMARY
CHEBI
48509
Created by admin on Mon Mar 31 23:34:15 GMT 2025 , Edited by admin on Mon Mar 31 23:34:15 GMT 2025
PRIMARY
CAS
358-23-6
Created by admin on Mon Mar 31 23:34:15 GMT 2025 , Edited by admin on Mon Mar 31 23:34:15 GMT 2025
PRIMARY
ECHA (EC/EINECS)
206-616-8
Created by admin on Mon Mar 31 23:34:15 GMT 2025 , Edited by admin on Mon Mar 31 23:34:15 GMT 2025
PRIMARY
MERCK INDEX
m11120
Created by admin on Mon Mar 31 23:34:15 GMT 2025 , Edited by admin on Mon Mar 31 23:34:15 GMT 2025
PRIMARY Merck Index
EPA CompTox
DTXSID501014629
Created by admin on Mon Mar 31 23:34:15 GMT 2025 , Edited by admin on Mon Mar 31 23:34:15 GMT 2025
PRIMARY
WIKIPEDIA
Trifluoromethanesulfonic anhydride
Created by admin on Mon Mar 31 23:34:15 GMT 2025 , Edited by admin on Mon Mar 31 23:34:15 GMT 2025
PRIMARY
PUBCHEM
67749
Created by admin on Mon Mar 31 23:34:15 GMT 2025 , Edited by admin on Mon Mar 31 23:34:15 GMT 2025
PRIMARY