U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C7H14N2O2S
Molecular Weight 190.263
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of ALDICARB

SMILES

CNC(=O)ON=CC(C)(C)SC

InChI

InChIKey=QGLZXHRNAYXIBU-UHFFFAOYSA-N
InChI=1S/C7H14N2O2S/c1-7(2,12-4)5-9-11-6(10)8-3/h5H,1-4H3,(H,8,10)

HIDE SMILES / InChI
Molecular Formula C7H14N2O2S
Molecular Weight 190.263
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE

Approval Year

Unknown
149124
PubMed

PubMed

TitleDatePubMed
Exacerbation of symptoms in agricultural pesticide applicators with asthma.
2014-05
Investigation of kinetic interactions between approved oximes and human acetylcholinesterase inhibited by pesticide carbamates.
2013-12-05
Human alpha- and beta-NRXN1 isoforms rescue behavioral impairments of Caenorhabditis elegans neurexin-deficient mutants.
2013-06
The conserved SKN-1/Nrf2 stress response pathway regulates synaptic function in Caenorhabditis elegans.
2013-03
Selenium induces cholinergic motor neuron degeneration in Caenorhabditis elegans.
2012-10
Regulation of neuronal APL-1 expression by cholesterol starvation.
2012
Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets.
2011-03-28
Esterase metabolism of cholinesterase inhibitors using rat liver in vitro.
2011-03-15
Application of physiologically based modelling and transcriptomics to probe the systems toxicology of aldicarb for Caenorhabditis elegans (Maupas 1900).
2011-03
Caenorhabditis elegans bicarbonate transporter ABTS-1 is involved in arsenite toxicity and cholinergic signaling.
2010-05-17
The evolutionarily conserved gene LNP-1 is required for synaptic vesicle trafficking and synaptic transmission.
2008-02
Caenorhabditis elegans intersectin: a synaptic protein regulating neurotransmission.
2007-12
Choline transport and de novo choline synthesis support acetylcholine biosynthesis in Caenorhabditis elegans cholinergic neurons.
2007-09
Pesticide use and colorectal cancer risk in the Agricultural Health Study.
2007-07-15
Pesticides and other agricultural factors associated with self-reported farmer's lung among farm residents in the Agricultural Health Study.
2007-05
PKC-1 regulates secretion of neuropeptides.
2007-01
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.
2006-11
SNARE complex zero layer residues are not critical for N-ethylmaleimide-sensitive factor-mediated disassembly.
2006-05-26
Presynaptic UNC-31 (CAPS) is required to activate the G alpha(s) pathway of the Caenorhabditis elegans synaptic signaling network.
2006-02
Effect of carbamate esters on neurite outgrowth in differentiating human SK-N-SH neuroblastoma cells.
2006-01-05
Analysis of synaptic transmission in Caenorhabditis elegans using an aldicarb-sensitivity assay.
2006
Systematic analysis of genes required for synapse structure and function.
2005-07-28
A Na+/Cl- -coupled GABA transporter, GAT-1, from Caenorhabditis elegans: structural and functional features, specific expression in GABA-ergic neurons, and involvement in muscle function.
2005-01-21
Age dependence of organophosphate and carbamate neurotoxicity in the postnatal rat: extrapolation to the human.
2004-04-15
Insulinoma-Associated Protein IA-2, a Vesicle Transmembrane Protein, Genetically Interacts with UNC-31/CAPS and Affects Neurosecretion in Caenorhabditis elegans.
2004-03-24
Selective effects of carbamate pesticides on rat neuronal nicotinic acetylcholine receptors and rat brain acetylcholinesterase.
2003-12-01
The stn-1 syntrophin gene of C.elegans is functionally related to dystrophin and dystrobrevin.
2003-10-03
Genetic and cellular basis for acetylcholine inhibition of Caenorhabditis elegans egg-laying behavior.
2003-09-03
Critical residues of the Caenorhabditis elegans unc-2 voltage-gated calcium channel that affect behavioral and physiological properties.
2003-07-23
Regulation of distinct muscle behaviors controls the C. elegans male's copulatory spicules during mating.
2001-12-14
The Eps15 C. elegans homologue EHS-1 is implicated in synaptic vesicle recycling.
2001-08
Mitochondrial expression and function of GAS-1 in Caenorhabditis elegans.
2001-06-08
The diabetes autoantigen ICA69 and its Caenorhabditis elegans homologue, ric-19, are conserved regulators of neuroendocrine secretion.
2000-10
RIC-8 (Synembryn): a novel conserved protein that is required for G(q)alpha signaling in the C. elegans nervous system.
2000-08
Differential toxicities of organophosphate and carbamate insecticides in the nestling European starling (Sturnus vulgaris).
2000-08
Inhibition of 17 beta-estradiol and progesterone activity in human breast and endometrial cancer cells by carbamate insecticides.
1997
Carbamate poisoning and oxime treatment in children: a clinical and laboratory study.
1994-04
Inhibition of interleukin 2 driven proliferation of mouse CTLL2 cells, by selected carbamate and organophosphate insecticides and congeners of carbaryl.
1993-03-01
Patents

Patents

JP2000146941A
2
JP2002255815A
2
JP2002508316A
4
JP2002541078A
2
JP2003525901A
2
JP2004503586A
3
JP2005523338A
2
JP2006520392A
6
JP2006525251A
26
JP2007507430A
13
JP2007532499A
2
JP2008509189A
189
JP2008531514A
9
JP2010209048A
2
JP2010506598A
3
JP2010519905A
3
JP2010519906A
3
JP2010519907A
3
JP2010519911A
3
JP2010519912A
3
JP2010519913A
3
JP2010524483A
52
JP2011509971A
151
JP2011524881A
3
JP2011526599A
45
JP2011527307A
41
JP2012500223A
2
JP2012500824A
79
JP2668232B2
2
JP2755403B2
2
JP2793312B2
2
JP3511139B2
2
JP4662775B2
2
JP4669225B2
2
JP4673837B2
32
JP4750804B2
9
JP4809244B2
2
JPH00656888A
2
JPH00656889A
2
JPH00856686A
2
JPH00959112A
3
JPH02157293A
4
JPH0241366A
2
JPH03101696A
2
JPH0543561A
2
JPH06167730A
2
JPH06199893A
2
JPH06228068A
2
JPH0656888A
2
JPH0656889A
2
JPH08503957A
2
Substance Class Chemical
Created
by admin
on Mon Mar 31 17:47:59 GMT 2025
Edited
by admin
on Mon Mar 31 17:47:59 GMT 2025
Record UNII
8V071SH05P
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TEMIK
Preferred Name English
ALDICARB
HSDB   ISO   MI  
Common Name English
2-METHYL-2-(METHYLTHIO)PROPANAL O-((METHYLAMINO)CARBONYL)OXIME
Systematic Name English
UC-21149
Common Name English
ALDICARB [ISO]
Common Name English
ALDICARB [HSDB]
Common Name English
2-METHYL-2-(METHYLTHIO)PROPIONALDEHYDE O-(METHYLCARBAMOYL)OXIME
Systematic Name English
ALDICARB [IARC]
Common Name English
ALDICARB [MI]
Common Name English
NSC-379586
Code English
Classification Tree Code System Code
EPA PESTICIDE CODE 98301
Created by admin on Mon Mar 31 17:47:59 GMT 2025 , Edited by admin on Mon Mar 31 17:47:59 GMT 2025
Code System Code Type Description
NCI_THESAURUS
C163578
Created by admin on Mon Mar 31 17:47:59 GMT 2025 , Edited by admin on Mon Mar 31 17:47:59 GMT 2025
PRIMARY
CAS
116-06-3
Created by admin on Mon Mar 31 17:47:59 GMT 2025 , Edited by admin on Mon Mar 31 17:47:59 GMT 2025
PRIMARY
MESH
D000448
Created by admin on Mon Mar 31 17:47:59 GMT 2025 , Edited by admin on Mon Mar 31 17:47:59 GMT 2025
PRIMARY
MERCK INDEX
m1485
Created by admin on Mon Mar 31 17:47:59 GMT 2025 , Edited by admin on Mon Mar 31 17:47:59 GMT 2025
PRIMARY Merck Index
HSDB
1510
Created by admin on Mon Mar 31 17:47:59 GMT 2025 , Edited by admin on Mon Mar 31 17:47:59 GMT 2025
PRIMARY
DAILYMED
8V071SH05P
Created by admin on Mon Mar 31 17:47:59 GMT 2025 , Edited by admin on Mon Mar 31 17:47:59 GMT 2025
PRIMARY
ECHA (EC/EINECS)
204-123-2
Created by admin on Mon Mar 31 17:47:59 GMT 2025 , Edited by admin on Mon Mar 31 17:47:59 GMT 2025
PRIMARY
CHEBI
2555
Created by admin on Mon Mar 31 17:47:59 GMT 2025 , Edited by admin on Mon Mar 31 17:47:59 GMT 2025
PRIMARY
PUBCHEM
2086
Created by admin on Mon Mar 31 17:47:59 GMT 2025 , Edited by admin on Mon Mar 31 17:47:59 GMT 2025
PRIMARY
SMS_ID
100000127494
Created by admin on Mon Mar 31 17:47:59 GMT 2025 , Edited by admin on Mon Mar 31 17:47:59 GMT 2025
PRIMARY
NSC
379586
Created by admin on Mon Mar 31 17:47:59 GMT 2025 , Edited by admin on Mon Mar 31 17:47:59 GMT 2025
PRIMARY
WIKIPEDIA
ALDICARB
Created by admin on Mon Mar 31 17:47:59 GMT 2025 , Edited by admin on Mon Mar 31 17:47:59 GMT 2025
PRIMARY
FDA UNII
8V071SH05P
Created by admin on Mon Mar 31 17:47:59 GMT 2025 , Edited by admin on Mon Mar 31 17:47:59 GMT 2025
PRIMARY
EPA CompTox
DTXSID0039223
Created by admin on Mon Mar 31 17:47:59 GMT 2025 , Edited by admin on Mon Mar 31 17:47:59 GMT 2025
PRIMARY
ALANWOOD
aldicarb
Created by admin on Mon Mar 31 17:47:59 GMT 2025 , Edited by admin on Mon Mar 31 17:47:59 GMT 2025
PRIMARY
EVMPD
SUB33520
Created by admin on Mon Mar 31 17:47:59 GMT 2025 , Edited by admin on Mon Mar 31 17:47:59 GMT 2025
PRIMARY
Related Record Type Details
Structure of ALDOXYCARB
METABOLITE -> PARENT
ALDICARB SULFOXIDE
METABOLITE -> PARENT
NIH
NCATS
PRIVACY NOTICE
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966