DULCIN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H12N2O2
Molecular Weight	180.2038
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOC1=CC=C(NC(N)=O)C=C1

InChI

InChIKey=GGLIEWRLXDLBBF-UHFFFAOYSA-N

InChI=1S/C9H12N2O2/c1-2-13-8-5-3-7(4-6-8)11-9(10)12/h3-6H,2H2,1H3,(H3,10,11,12)

HIDE SMILES / InChI

Molecular Formula	C9H12N2O2
Molecular Weight	180.2038
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Retention behaviour of some high-intensity sweeteners on different SPE sorbents.	2010-10-15	20875571
Determination of nine intense sweeteners in foodstuffs by high-performance liquid chromatography and evaporative light-scattering detection: interlaboratory study.	2009-04-23	19382579
Behavioral genetics and taste.	2007-09-18	17903279
Simultaneous determination of nine intense sweeteners in foodstuffs by high performance liquid chromatography and evaporative light scattering detection--development and single-laboratory validation.	2007-07-20	17540386
Identification of the human liver UDP-glucuronosyltransferase involved in the metabolism of p-ethoxyphenylurea (dulcin).	2007-03	16897040
Taste responses to sweet stimuli in alpha-gustducin knockout and wild-type mice.	2006-07	16740645
Stimulus-induced increase of taste responses in the hamster chorda tympani by repeated exposure to 'novel' tastants.	2005-12	16112777
Peripheral gustatory processing of sweet stimuli by golden hamsters.	2005-07-15	15925146
[Analysis of nine kinds of sweeteners in foods by LC/MS].	2005-06	16042292
Identification of the rabbit liver UDP-glucuronosyltransferase catalyzing the glucuronidation of 4-ethoxyphenylurea (dulcin).	2004-12	15448114
Behavioral study in the gray mouse lemur (Microcebus murinus) using compounds considered sweet by humans.	2004-01	14752812
Comparison of the responses of the chorda tympani and glossopharyngeal nerves to taste stimuli in C57BL/6J mice.	2003-03-04	12617752
Mammalian sweet taste receptors.	2001-08-10	11509186

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:36:05 GMT 2025` Edited by `admin` on `Mon Mar 31 17:36:05 GMT 2025`
Record UNII	8U78KF577Z
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

VALZIN

Preferred Name

English

DULCIN

Common Name

English

(P-ETHOXYPHENYL)UREA

Common Name

English

P-PHENETYLUREA

Common Name

English

N-(4-ETHOXYPHENYL)UREA

Systematic Name

English

DULCIN [IARC]

Common Name

English

P-PHENETOLCARBAMIDE

Common Name

English

UREA,(4-ETHOXYPHENYL)-

Common Name

English

P-ETHOXYPHENYLUREA

Common Name

English

DULCIN [MI]

Common Name

English

P-PHENETOLECARBAMIDE

Common Name

English

PHENETOLCARBAMIDE

Systematic Name

English

SUCROL

Common Name

English

NSC-1839

Code

English

1-(4-ETHOXYPHENYL)UREA

Systematic Name

English

4-ETHOXYPHENYL)UREA

Common Name

English

4-UREIDOPHENETOLE

Systematic Name

English

UREA, (P-ETHOXYPHENYL)-

Common Name

English

Classification Tree Code System Code

CFR

21 CFR 189.145