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Details

Stereochemistry ACHIRAL
Molecular Formula C2H3F3O
Molecular Weight 100.0398
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2,2,2-TRIFLUOROETHANOL

SMILES

OCC(F)(F)F

InChI

InChIKey=RHQDFWAXVIIEBN-UHFFFAOYSA-N
InChI=1S/C2H3F3O/c3-2(4,5)1-6/h6H,1H2

HIDE SMILES / InChI

Molecular Formula C2H3F3O
Molecular Weight 100.0398
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Solvent-dependent C-OH homolysis and heterolysis in electronically excited 9-fluorenol: the life and solvation time of the 9-fluorenyl cation in water.
2001 Apr 17
Chichibabin indolizine synthesis revisited: synthesis of indolizinones by solvolysis of 4-alkoxycarbonyl-3-oxotetrahydroquinolizinium ylides.
2001 Apr 20
Purification and structural analysis of the hepatitis B virus preS1 expressed from Escherichia coli.
2001 Apr 6
Stepwise proteolytic removal of the beta subdomain in alpha-lactalbumin. The protein remains folded and can form the molten globule in acid solution.
2001 Aug
Fluorescence study of conformational properties of melanotropins labeled with aminobenzoic acid.
2001 Aug
Induction of secondary structure in a COOH-terminal peptide of histone H1 by interaction with the DNA: an infrared spectroscopy study.
2001 Aug 17
Conformational intermediate of the amyloidogenic protein beta 2-microglobulin at neutral pH.
2001 Aug 31
Conserved guanine-guanine stacking in tetraplex and duplex DNA.
2001 Dec
Solution conditions can promote formation of either amyloid protofilaments or mature fibrils from the HypF N-terminal domain.
2001 Dec
Solvent effect on the isomeric equilibrium of carbohydrates: the superior ability of 2,2,2-trifluoroethanol for intramolecular hydrogen bond stabilization.
2001 Dec 19
Solution structure of the p53 regulatory domain of the p19Arf tumor suppressor protein.
2001 Feb 27
Reactivation and refolding of rabbit muscle creatine kinase denatured in 2,2,2-trifluoroethanol solutions.
2001 Feb 9
Molecular dynamics simulation of the antimicrobial salivary peptide histatin-5 in water and in trifluoroethanol: a microscopic description of the water destructuring effect.
2001 Jul
Elongation of the BH8 beta-hairpin peptide: Electrostatic interactions in beta-hairpin formation and stability.
2001 Jul
Trifluoroethanol-assisted protein folding: fragment 53--103 of bovine alpha-lactalbumin.
2001 Jul 9
Effects of salt and denaturant on structure of the amino terminal alpha-helical segment of an antibacterial peptide dermaseptin and its binding to model membranes.
2001 Jun
Comparison of the aggregation properties, secondary structure and apoptotic effects of wild-type, Flemish and Dutch N-terminally truncated amyloid beta peptides.
2001 Jun
Protein anatomy: structure and function of peptide fragments corresponding to the secondary structure units of barnase.
2001 Jun
Separation of perfluoroalkylsulfinic acids and perfluoroalkylsulfonic acids by ion-exclusion chromatography.
2001 Jun 22
Factors contributing to the fusogenic potency of foamy virus.
2001 Jun 22
Conformational model for the consensus V3 loop of the envelope protein gp120 of HIV-1 in a 20% trifluoroethanol/water solution.
2001 May
Observation of the closing of individual hydrogen bonds during TFE-induced helix formation in a peptide.
2001 May
Conformational properties of five peptides corresponding to the entire sequence of glutathione transferase domain II.
2001 May 1
Role of the core region of the PufX protein in inhibition of reconstitution of the core light-harvesting complexes of Rhodobacter sphaeroides and Rhodobacter capsulatus.
2001 May 15
Molten-globule structure and membrane binding of the N-terminal protease-resistant domain (63-193) of the steroidogenic acute regulatory protein (StAR).
2001 May 15
Evidence for an alpha-helix --> pi-bulge helicity modulation for the neu/erbB-2 membrane-spanning segment. A 1H NMR and circular dichroism study.
2001 May 29
Study of the conformational transition of A beta(1-42) using D-amino acid replacement analogues.
2001 May 8
Evidence of secondary structure by high-resolution magic angle spinning NMR spectroscopy of a bioactive peptide bound to different solid supports.
2001 May 9
Helix-stabilizing effects of the pentapeptide KIFMK and its related peptides on the sodium channel inactivation gate peptides.
2001 Nov
Calcium-dependent stabilization of the central sequence between Met(76) and Ser(81) in vertebrate calmodulin.
2001 Nov
Triethylborane-induced bromine atom-transfer radical addition in aqueous media: study of the solvent effect on radical addition reactions.
2001 Nov 16
Conformational changes in pediocin AcH upon vesicle binding and approximation of the membrane-bound structure in detergent micelles.
2001 Nov 20
Antimicrobial peptides isolated from skin secretions of the diploid frog, Xenopus tropicalis (Pipidae).
2001 Nov 26
Anoplin, a novel antimicrobial peptide from the venom of the solitary wasp Anoplius samariensis.
2001 Nov 26
Unique selectivity of perfluorinated stationary phases with 2,2,2-trifluoroethanol as organic mobile phase modifier.
2001 Nov 9
Conformation and other biophysical properties of cyclic antimicrobial peptides in aqueous solutions.
2001 Oct
Structural study of novel antimicrobial peptides, nigrocins, isolated from Rana nigromaculata.
2001 Oct 19
Interrelationships among biological activity, disulfide bonds, secondary structure, and metal ion binding for a chemically synthesized 34-amino-acid peptide derived from alpha-fetoprotein.
2001 Oct 3
The solution structure and heme binding of the presequence of murine 5-aminolevulinate synthase.
2001 Sep 14
Methylated mono- and di(ethylene glycol)-functionalized beta-sheet forming polypeptides.
2001 Spring
Characterization and modelling of the hydrophobic domain of a sunflower oleosin.
2002 Feb
Comparison between UV Raman and circular dichroism detection of short alpha helices in bombolitin III.
2002 Feb 12
Conformational mapping of the N-terminal peptide of HIV-1 gp41 in membrane environments using (13)C-enhanced Fourier transform infrared spectroscopy.
2002 Feb 15
Peptide models of folding initiation sites of bovine beta-lactoglobulin: identification of nativelike hydrophobic interactions involving G and H strands.
2002 Feb 26
Extreme stability of helices formed by water-soluble poly-N-substituted glycines (polypeptoids) with alpha-chiral side chains.
2002 Jan
The anti-toxin ParD of plasmid RK2 consists of two structurally distinct moieties and belongs to the ribbon-helix-helix family of DNA-binding proteins.
2002 Jan 1
Human stefin B readily forms amyloid fibrils in vitro.
2002 Jan 31
Impact of single-residue mutations on the structure and function of ovispirin/novispirin antimicrobial peptides.
2002 Mar
Temperature-induced extended helix/random coil transitions in a group 1 late embryogenesis-abundant protein from soybean.
2002 Mar
Product binding to the diiron(III) and mixed-valence diiron centers of methane monooxygenase hydroxylase studied by (1,2)H and (19)F ENDOR spectroscopy.
2002 Mar 20
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:11:50 UTC 2023
Edited
by admin
on Fri Dec 15 15:11:50 UTC 2023
Record UNII
8T8I76KYF1
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
2,2,2-TRIFLUOROETHANOL
Systematic Name English
TRIFLUOROETHANOL
MI  
Systematic Name English
NSC-451
Code English
ETHANOL, 2,2,2-TRIFLUORO-
Systematic Name English
TRIFLUOROETHANOL [MI]
Common Name English
2,2,2-TRIFLUOROETHYL ALCOHOL
Systematic Name English
Code System Code Type Description
ECHA (EC/EINECS)
200-913-6
Created by admin on Fri Dec 15 15:11:50 UTC 2023 , Edited by admin on Fri Dec 15 15:11:50 UTC 2023
PRIMARY
MESH
D014270
Created by admin on Fri Dec 15 15:11:50 UTC 2023 , Edited by admin on Fri Dec 15 15:11:50 UTC 2023
PRIMARY
WIKIPEDIA
2,2,2-TRIFLUOROETHANOL
Created by admin on Fri Dec 15 15:11:50 UTC 2023 , Edited by admin on Fri Dec 15 15:11:50 UTC 2023
PRIMARY
CHEBI
42330
Created by admin on Fri Dec 15 15:11:50 UTC 2023 , Edited by admin on Fri Dec 15 15:11:50 UTC 2023
PRIMARY
NSC
451
Created by admin on Fri Dec 15 15:11:50 UTC 2023 , Edited by admin on Fri Dec 15 15:11:50 UTC 2023
PRIMARY
MERCK INDEX
m11118
Created by admin on Fri Dec 15 15:11:50 UTC 2023 , Edited by admin on Fri Dec 15 15:11:50 UTC 2023
PRIMARY Merck Index
PUBCHEM
6409
Created by admin on Fri Dec 15 15:11:50 UTC 2023 , Edited by admin on Fri Dec 15 15:11:50 UTC 2023
PRIMARY
CAS
75-89-8
Created by admin on Fri Dec 15 15:11:50 UTC 2023 , Edited by admin on Fri Dec 15 15:11:50 UTC 2023
PRIMARY
EPA CompTox
DTXSID0021751
Created by admin on Fri Dec 15 15:11:50 UTC 2023 , Edited by admin on Fri Dec 15 15:11:50 UTC 2023
PRIMARY
FDA UNII
8T8I76KYF1
Created by admin on Fri Dec 15 15:11:50 UTC 2023 , Edited by admin on Fri Dec 15 15:11:50 UTC 2023
PRIMARY
DRUG BANK
DB03226
Created by admin on Fri Dec 15 15:11:50 UTC 2023 , Edited by admin on Fri Dec 15 15:11:50 UTC 2023
PRIMARY