2,2,2-TRIFLUOROETHANOL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C2H3F3O
Molecular Weight	100.0398
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OCC(F)(F)F

InChI

InChIKey=RHQDFWAXVIIEBN-UHFFFAOYSA-N

InChI=1S/C2H3F3O/c3-2(4,5)1-6/h6H,1H2

HIDE SMILES / InChI

Molecular Formula	C2H3F3O
Molecular Weight	100.0398
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
The membrane-proximal tryptophan-rich region of the HIV glycoprotein, gp41, forms a well-defined helix in dodecylphosphocholine micelles.	2001 Aug 14	11583156
Conserved guanine-guanine stacking in tetraplex and duplex DNA.	2001 Dec	11820398
FTIR studies of intermolecular hydrogen bonding in halogenated ethanols.	2001 Dec	11789877
Solution conditions can promote formation of either amyloid protofilaments or mature fibrils from the HypF N-terminal domain.	2001 Dec	11714922
Solvent effect on the isomeric equilibrium of carbohydrates: the superior ability of 2,2,2-trifluoroethanol for intramolecular hydrogen bond stabilization.	2001 Dec 19	11741425
DNA-induced alpha-helical structure in the NH2-terminal domain of histone H1.	2001 Dec 7	11584004
Effects of salt and denaturant on structure of the amino terminal alpha-helical segment of an antibacterial peptide dermaseptin and its binding to model membranes.	2001 Jun	11693375
Helix-stabilizing effects of the pentapeptide KIFMK and its related peptides on the sodium channel inactivation gate peptides.	2001 Nov	11892850
N-Terminal domain of HTLV-I integrase. Complexation and conformational studies of the zinc finger.	2001 Nov	11763363
Calcium-dependent stabilization of the central sequence between Met(76) and Ser(81) in vertebrate calmodulin.	2001 Nov	11606301
Triethylborane-induced bromine atom-transfer radical addition in aqueous media: study of the solvent effect on radical addition reactions.	2001 Nov 16	11701036
Conformational changes in pediocin AcH upon vesicle binding and approximation of the membrane-bound structure in detergent micelles.	2001 Nov 20	11705396
Antimicrobial peptides isolated from skin secretions of the diploid frog, Xenopus tropicalis (Pipidae).	2001 Nov 26	11738090
Anoplin, a novel antimicrobial peptide from the venom of the solitary wasp Anoplius samariensis.	2001 Nov 26	11738089
Exendin-4 and glucagon-like-peptide-1: NMR structural comparisons in the solution and micelle-associated states.	2001 Nov 6	11683627
Unique selectivity of perfluorinated stationary phases with 2,2,2-trifluoroethanol as organic mobile phase modifier.	2001 Nov 9	11758748
Conformation and other biophysical properties of cyclic antimicrobial peptides in aqueous solutions.	2001 Oct	11606214
Intermolecular (1)H[(19)F] NOEs in studies of fluoroalcohol-induced conformations of peptides and proteins.	2001 Oct	11567580
The roles of turn formation and cross-strand interactions in fibrillization of peptides derived from the OspA single-layer beta-sheet.	2001 Oct	11567099
Structural study of novel antimicrobial peptides, nigrocins, isolated from Rana nigromaculata.	2001 Oct 19	11682065
Interrelationships among biological activity, disulfide bonds, secondary structure, and metal ion binding for a chemically synthesized 34-amino-acid peptide derived from alpha-fetoprotein.	2001 Oct 3	11687299
Acidity of carboxylic acids: a rebuttal and redefinition.	2001 Oct 3	11572676
Methylated mono- and di(ethylene glycol)-functionalized beta-sheet forming polypeptides.	2001 Spring	11749148
Expression, purification, and structural characterization of human histone H4.	2002 Apr	11922758
The chain length dependence of helix formation of the second transmembrane domain of a G protein-coupled receptor of Saccharomyces cerevisiae.	2002 Apr 26	11854278
NMR conformational analysis of antide, a potent antagonist of the gonadotropin releasing hormone.	2002 Apr 3	11916429
Characterization and modelling of the hydrophobic domain of a sunflower oleosin.	2002 Feb	11925038
Uncoupled analysis of secondary and tertiary protein structure by circular dichroism and electrospray ionization mass spectrometry.	2002 Feb	11857763
SMAP-29 has two LPS-binding sites and a central hinge.	2002 Feb	11856344
An inducible helix-Gly-Gly-helix motif in the N-terminal domain of histone H1e: a CD and NMR study.	2002 Feb	11790831
Hints of nonhierarchical folding of acidic fibroblast growth factor.	2002 Feb 12	11827539
Comparison between UV Raman and circular dichroism detection of short alpha helices in bombolitin III.	2002 Feb 12	11827535
Conformational mapping of the N-terminal peptide of HIV-1 gp41 in membrane environments using (13)C-enhanced Fourier transform infrared spectroscopy.	2002 Feb 15	11853678
An ELISA technique for quantification of surfactant apoprotein (SP)-C in bronchoalveolar lavage fluid.	2002 Feb 15	11850338
C [bond] H activation by cationic platinum(II) complexes: ligand electronic and steric effects.	2002 Feb 20	11841307
Anhydrodihydroartemisinin and its 10-trifluoromethyl analogue: access to novel d-ring-contracted artemisinin trifluoromethyl ketones.	2002 Feb 22	11846670
Peptide models of folding initiation sites of bovine beta-lactoglobulin: identification of nativelike hydrophobic interactions involving G and H strands.	2002 Feb 26	11851426
Photosolvolysis of (E)-styryl(phenyl)iodonium tetrafluoroborate. Generation and reactivity of a primary vinyl Cation.	2002 Feb 8	11856008
Extreme stability of helices formed by water-soluble poly-N-substituted glycines (polypeptoids) with alpha-chiral side chains.	2002 Jan	11754344
The anti-toxin ParD of plasmid RK2 consists of two structurally distinct moieties and belongs to the ribbon-helix-helix family of DNA-binding proteins.	2002 Jan 1	11743881
A ruthenium(II) tris(bipyridyl) amino acid: synthesis and direct incorporation into an alpha-helical peptide by solid-phase synthesis.	2002 Jan 28	11800628
Human stefin B readily forms amyloid fibrils in vitro.	2002 Jan 31	11825603
Impact of single-residue mutations on the structure and function of ovispirin/novispirin antimicrobial peptides.	2002 Mar	11932493
Temperature-induced extended helix/random coil transitions in a group 1 late embryogenesis-abundant protein from soybean.	2002 Mar	11891239
Detecting equilibrium cytochrome c folding intermediates by electrospray ionisation mass spectrometry: two partially folded forms populate the molten-globule state.	2002 Mar	11847268
Antimicrobial peptides with atypical structural features from the skin of the Japanese brown frog Rana japonica.	2002 Mar	11835990
Product binding to the diiron(III) and mixed-valence diiron centers of methane monooxygenase hydroxylase studied by (1,2)H and (19)F ENDOR spectroscopy.	2002 Mar 20	11890816
Influence of backbone conformation on protein aggregation.	2002 Mar 6	11866599
HIV-1 encoded virus protein U (Vpu) solution structure of the 41-62 hydrophilic region containing the phosphorylated sites Ser52 and Ser56.	2002 Mar 8	11893391
Conformational analysis of the androgen receptor amino-terminal domain involved in transactivation. Influence of structure-stabilizing solutes and protein-protein interactions.	2002 May 31	11896058

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:11:50 UTC 2023` Edited by `admin` on `Fri Dec 15 15:11:50 UTC 2023`
Record UNII	8T8I76KYF1
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

2,2,2-TRIFLUOROETHANOL

Systematic Name

English

TRIFLUOROETHANOL

Systematic Name

English

NSC-451

Code

English

ETHANOL, 2,2,2-TRIFLUORO-

Systematic Name

English

TRIFLUOROETHANOL [MI]

Common Name

English

2,2,2-TRIFLUOROETHYL ALCOHOL

Systematic Name

English

Code System Code Type Description

ECHA (EC/EINECS)

200-913-6