RS-8359 HYDROCHLORIDE

Cl.OC1CCC2=C1N=CN=C2NC3=CC=C(C=C3)C#N

InChIKey=TTZWBGBYPWZYSC-UHFFFAOYSA-N

InChI=1S/C14H12N4O.ClH/c15-7-9-1-3-10(4-2-9)18-14-11-5-6-12(19)13(11)16-8-17-14;/h1-4,8,12,19H,5-6H2,(H,16,17,18);1H

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
In vitro-in vivo correlation for intrinsic clearance for drugs metabolized by human aldehyde oxidase.	2010-08	20444863
Genetic polymorphism of aldehyde oxidase in Donryu rats.	2007-05	17293383
Chiral inversion of RS-8359: a selective and reversible MAO-A inhibitor via oxido-reduction of keto-alcohol.	2006-09	16823812
Enantioselective 2-hydroxylation of RS-8359, a selective and reversible MAO-A inhibitor, by cytochrome P450 in mouse and rat liver microsomes.	2006-08	16642492
Stereoselective pharmacokinetics of RS-8359, a selective and reversible MAO-A inhibitor, by species-dependent drug-metabolizing enzymes.	2005-03	15704197

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:51:14 GMT 2025` Edited by `admin` on `Mon Mar 31 21:51:14 GMT 2025`
Record UNII	8T4B4CQD32
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

BENZONITRILE, 4-((6,7-DIHYDRO-7-HYDROXY-5H-CYCLOPENTAPYRIMIDIN-4-YL)AMINO)-, MONOHYDROCHLORIDE

Preferred Name

English

RS-8359 HYDROCHLORIDE

Common Name

English

Code System Code Type Description

PUBCHEM

86278292

Created by admin on Mon Mar 31 21:51:14 GMT 2025 , Edited by admin on Mon Mar 31 21:51:14 GMT 2025

PRIMARY

FDA UNII

8T4B4CQD32

Created by admin on Mon Mar 31 21:51:14 GMT 2025 , Edited by admin on Mon Mar 31 21:51:14 GMT 2025

PRIMARY

CAS

214148-18-2

Created by admin on Mon Mar 31 21:51:14 GMT 2025 , Edited by admin on Mon Mar 31 21:51:14 GMT 2025

PRIMARY

Related Record Type Details


					79U9T1HIX9

RS-8359

ACTIVE MOIETY