Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C6H3N3O9S |
| Molecular Weight | 293.168 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OS(=O)(=O)C1=C(C=C(C=C1[N+]([O-])=O)[N+]([O-])=O)[N+]([O-])=O
InChI
InChIKey=NHJVRSWLHSJWIN-UHFFFAOYSA-N
InChI=1S/C6H3N3O9S/c10-7(11)3-1-4(8(12)13)6(19(16,17)18)5(2-3)9(14)15/h1-2H,(H,16,17,18)
| Molecular Formula | C6H3N3O9S |
| Molecular Weight | 293.168 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Polyethylene glycol enhances colonic barrier function and ameliorates experimental colitis in rats. | 2007-06 |
|
| Mechanism of reduced colonic contractility in experimental colitis: role of sarcoplasmic reticulum pump isoform-2. | 2007-04 |
|
| Structural adaptations in the murine colon microcirculation associated with hapten-induced inflammation. | 2007-04 |
|
| Neonatal immune challenge exacerbates experimental colitis in adult rats: potential role for TNF-alpha. | 2007-01 |
|
| Changes in allergenicity and digestibility of squid tropomyosin during the Maillard reaction with ribose. | 2006-12-13 |
|
| Lactobacillus casei prevents the upregulation of ICAM-1 expression and leukocyte recruitment in experimental colitis. | 2006-12 |
|
| Different susceptibilities of spontaneous rhythmicity and myogenic contractility to intestinal muscularis inflammation in the hapten-induced colitis. | 2006-11 |
|
| Long-term study of TNBS-induced colitis in rats: focus on mast cells. | 2006-10 |
|
| Contractile activity of lymphatic vessels is altered in the TNBS model of guinea pig ileitis. | 2006-10 |
|
| ADOA3R as a therapeutic target in experimental colitis: proof by validated high-density oligonucleotide microarray analysis. | 2006-08 |
|
| Antisense therapy of MAdCAM-1 for trinitrobenzenesulfonic acid-induced murine colitis. | 2006-08 |
|
| Curcumin regulated shift from Th1 to Th2 in trinitrobenzene sulphonic acid-induced chronic colitis. | 2006-08 |
|
| Curcumin inhibits trinitrobenzene sulphonic acid-induced colitis in rats by activation of peroxisome proliferator-activated receptor gamma. | 2006-08 |
|
| Identification of Card15/Nod2 mRNA in intestinal tissue of experimentally induced colitis in rats. | 2006-07 |
|
| Role of TNF-alpha in muscularis inflammation and motility disorder in a TNBS-induced colitis model: clues from TNF-alpha-deficient mice. | 2006-07 |
|
| Curcumin-attenuated trinitrobenzene sulphonic acid induces chronic colitis by inhibiting expression of cyclooxygenase-2. | 2006-06-28 |
|
| The specific JNK inhibitor SP600125 targets tumour necrosis factor-alpha production and epithelial cell apoptosis in acute murine colitis. | 2006-05 |
|
| Scintigraphic imaging of experimental colitis with technetium-99m-infliximab in the rat. | 2006-04-28 |
|
| The effects of resveratrol, a phytoalexin derived from red wines, on chronic inflammation induced in an experimentally induced colitis model. | 2006-04 |
|
| Experimental colitis in mice and sensitization of converging visceral and somatic afferent pathways. | 2006-03 |
|
| Selective inhibition of phosphodiesterase-4 ameliorates chronic colitis and prevents intestinal fibrosis. | 2006-02 |
|
| Favorable response to subcutaneous administration of infliximab in rats with experimental colitis. | 2005-11-21 |
|
| Nanoparticles enhance therapeutic efficiency by selectively increased local drug dose in experimental colitis in rats. | 2005-10 |
|
| Effect of maillard reaction on allergenicity of scallop tropomyosin. | 2005-09-21 |
|
| Endogenous ADP-ribosylation for eukaryotic elongation factor 2: evidence of two different sites and reactions. | 2005-09-06 |
|
| Analysis of pregabalin at therapeutic concentrations in human plasma/serum by reversed-phase HPLC. | 2005-08 |
|
| cDNA array analysis of cytokines, chemokines, and receptors involved in the development of TNBS-induced colitis: homeostatic role of VIP. | 2005-07 |
|
| Chemical modification studies on alkaline phosphatase from pearl oyster (Pinctada fucata): a substrate reaction course analysis and involvement of essential arginine and lysine residues at the active site. | 2005-07 |
|
| Effect of the macrolide antibacterial drug, tylosin, on TNBS-induced colitis in the rat. | 2005-06 |
|
| Protection against 2,4,6-trinitrobenzenesulphonic acid-induced colonic inflammation in mice by the marine products bolinaquinone and petrosaspongiolide M. | 2005-05-15 |
|
| Bovine glycomacropeptide is anti-inflammatory in rats with hapten-induced colitis. | 2005-05 |
|
| Expression and significance of nuclear factor kappaB p65 in colon tissues of rats with TNBS-induced colitis. | 2005-03-28 |
|
| Preventive and therapeutic effects of NF-kappaB inhibitor curcumin in rats colitis induced by trinitrobenzene sulfonic acid. | 2005-03-28 |
|
| Vasoactive intestinal peptide impairs leucocyte migration but fails to modify experimental murine colitis. | 2005-03 |
|
| Uterine motor alterations and estrous cycle disturbances associated with colonic inflammation in the rat. | 2005-03 |
|
| Involvement of bone marrow-derived cells in healing of experimental colitis in rats. | 2005-01-22 |
|
| [Modulation of intestinal mucosal inflammatory factors by curcumin in rats with colitis]. | 2004-12 |
|
| Angiotensin II mediates acinar cell apoptosis during the development of rat pancreatic fibrosis by AT1R. | 2004-11 |
|
| Enteroendocrine cells and 5-HT availability are altered in mucosa of guinea pigs with TNBS ileitis. | 2004-11 |
|
| In vivo evaluation of 111In-labeled T-lymphocyte homing in experimental colitis. | 2004-10 |
|
| Two TTX-resistant Na+ currents in mouse colonic dorsal root ganglia neurons and their role in colitis-induced hyperexcitability. | 2004-10 |
|
| Neuronal activity and CRF receptor gene transcription in the brains of rats with colitis. | 2004-10 |
|
| Effects of tegaserod on Fos, substance P and calcitonin gene-related peptide expression induced by colon inflammation in lumbarsacral spinal cord. | 2004-06-15 |
|
| Colitis up-regulates local glucocorticoid activation and down-regulates inactivation in colonic tissue. | 2004-06 |
|
| Anti-inflammatory effect of acute stress on experimental colitis is mediated by cholecystokinin-B receptors. | 2004-05-21 |
|
| Characterization of the sensitizing potential of chemicals by in vitro analysis of dendritic cell activation and skin penetration. | 2004-05 |
|
| Quantitatively investigating monomethoxypolyethylene glycol modification of protein by capillary electrophoresis. | 2004-04-30 |
|
| Neonatal maternal deprivation triggers long term alterations in colonic epithelial barrier and mucosal immunity in rats. | 2004-04 |
|
| Effects of intrarectal and intraperitoneal N(G)-nitro-L-arginine methyl ester treatment in 2,4,6-trinitrobenzenesulfonic acid induced colitis in rats. | 2003-11 |
|
| Long-term evaluation of a rat model of chronic cholangitis resembling human primary sclerosing cholangitis. | 2003-11 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:04:32 GMT 2025
by
admin
on
Mon Mar 31 19:04:32 GMT 2025
|
| Record UNII |
8T3HQG2ZC4
|
| Record Status |
Validated (UNII)
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| Record Version |
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7856
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8T3HQG2ZC4
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53506
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Trinitrobenzenesulfonic acid
Created by
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DTXSID0043715
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127994
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2508-19-2
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11045
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219-717-7
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53063
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D014302
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