U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
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Approval Year

Substance Class Protein
Created
by admin
on Wed Apr 02 02:58:05 GMT 2025
Edited
by admin
on Wed Apr 02 02:58:05 GMT 2025
Protein Sub Type
Sequence Type COMPLETE
Record UNII
8RT5G5EY5Z
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8
Common Name English
ABCC8
Preferred Name English
SULFONYLUREA RECEPTOR 1
Common Name English
SUR-1
Common Name English
Code System Code Type Description
FDA UNII
8RT5G5EY5Z
Created by admin on Wed Apr 02 02:58:05 GMT 2025 , Edited by admin on Wed Apr 02 02:58:05 GMT 2025
PRIMARY
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_10
N 1_1049
Related Record Type Details
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
Glyburide stimulates insulin secretion through the closure of ATP-sensitive potassium channels decrease the K+ permeability of the cell membrane which leads to a depolarization of the cell, an enhanced Ca 2+ influx and the release of insulin
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
ACTIVATOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
INHIBITOR -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL