ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 02:58:05 GMT 2025` Edited by `admin` on `Wed Apr 02 02:58:05 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	8RT5G5EY5Z
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8

Common Name

English

ABCC8

Preferred Name

English

SULFONYLUREA RECEPTOR 1

Common Name

English

SUR-1

Common Name

English

Code System Code Type Description

FDA UNII

8RT5G5EY5Z

Created by admin on Wed Apr 02 02:58:05 GMT 2025 , Edited by admin on Wed Apr 02 02:58:05 GMT 2025

PRIMARY

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_10
N	1_1049

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					D86I0XLB13

MITIGLINIDE

INHIBITOR -> TARGET


					668Z8C33LU

REPAGLINIDE

INHIBITOR -> TARGET


					41X3PWK4O2

NATEGLINIDE

INHIBITOR -> TARGET


					SX6K58TVWC

GLYBURIDE

INHIBITOR -> TARGET

Comments:

Glyburide stimulates insulin secretion through the closure of ATP-sensitive potassium channels decrease the K+ permeability of the cell membrane which leads to a depolarization of the cell, an enhanced Ca 2+ influx and the release of insulin

Amount: