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National Institutes of Health
NCATS
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ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8
8RT5G5EY5Z
Other
General
Record Details
Names
4
Identifiers
1
Subunits
1
Glycosylation
2
Relationships
14
Characteristic Attributes
1
ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8
8RT5G5EY5Z
Other
General
Approval Year
Unknown
149,124
Record Details
Substance Class
Protein
Protein Sub Type
Sequence Type
COMPLETE
Record UNII
8RT5G5EY5Z
Record Status
Validated (UNII)
Record Version
10
9
8
7
6
5
4
3
2
1
Names
4
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entries
Name
Type
Language
Name
Type
Language
ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8
Common Name
English
ABCC8
Preferred Name
English
SULFONYLUREA RECEPTOR 1
Common Name
English
SUR-1
Common Name
English
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Identifiers
1
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Code System
Code
Type
Description
Code System
Code
Type
Description
FDA UNII
8RT5G5EY5Z
PRIMARY
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Subunits
1
Subunit 0
>SUBUNIT_0
Glycosylation
2
Glycosylation Type
HUMAN
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Glycosylation Link Type
Site
Glycosylation Link Type
Site
N
1_10
N
1_1049
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Relationships
14
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Related Record
Type
Details
Related Record
Type
Details
D86I0XLB13
MITIGLINIDE
INHIBITOR -> TARGET
668Z8C33LU
REPAGLINIDE
INHIBITOR -> TARGET
41X3PWK4O2
NATEGLINIDE
INHIBITOR -> TARGET
SX6K58TVWC
GLYBURIDE
INHIBITOR -> TARGET
Comments:
Glyburide stimulates insulin secretion through the closure of ATP-sensitive potassium channels decrease the K+ permeability of the cell membrane which leads to a depolarization of the cell, an enhanced Ca 2+ influx and the release of insulin
Amount:
X7WDT95N5C
GLIPIZIDE
INHIBITOR -> TARGET
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Characteristic Attributes
1
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entries
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
MOL_WEIGHT
CHEMICAL
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