MYRISTYL NICOTINATE

CCCCCCCCCCCCCCOC(=O)C1=CN=CC=C1

InChIKey=TVGLGJWCZSCAEM-UHFFFAOYSA-N

InChI=1S/C20H33NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-17-23-20(22)19-15-14-16-21-18-19/h14-16,18H,2-13,17H2,1H3

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
establishment of skin barrier 1 Target ID: GO:0061436 Sources: https://www.ncbi.nlm.nih.gov/pubmed/17927576	Activator 1430

PubMed

Title	Date	PubMed
A pilot study evaluating the efficacy of topically applied niacin derivatives for treatment of female pattern alopecia.	2005 Dec	17168873
Simultaneous determination of myristyl nicotinate, nicotinic acid, and nicotinamide in rabbit plasma by liquid chromatography-tandem mass spectrometry using methyl ethyl ketone as a deproteinization solvent.	2005 Dec 27	16275131
Analysis and stability study of myristyl nicotinate in dermatological preparations by high-performance liquid chromatography.	2007 Feb 19	17049429
A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin.	2007 Jun	17518989
Formulation compatibility of myristyl nicotinate with drugs used to treat dermatological conditions involving an impaired skin barrier.	2007 Nov	18058313
Effect of myristyl nicotinate on retinoic acid therapy for facial photodamage.	2007 Nov	17927576
Gateways to clinical trials.	2007 Oct	18040531

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:13:27 UTC 2023` Edited by `admin` on `Fri Dec 15 19:13:27 UTC 2023`
Record UNII	8QWM6I035C
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

MYRISTYL NICOTINATE

Official Name

English

3-PYRIDINECARBOXYLIC ACID, TETRADECYL ESTER

Common Name

English

MYRISTYL NICOTINATE [INCI]

Common Name

English

TETRADECYL NICOTINATE

Systematic Name

English

PRO-NAD

Brand Name

English

Classification Tree Code System Code

NCI_THESAURUS

C2459