DRAMEDILOL

Details

Stereochemistry	RACEMIC
Molecular Formula	C20H29N5O4
Molecular Weight	403.4754
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC=C(CCNCC(O)COC2=NN=C(NN=C(C)C)C=C2)C=C1OC

InChI

InChIKey=HLUGSJZJQJZYAE-UHFFFAOYSA-N

InChI=1S/C20H29N5O4/c1-14(2)22-23-19-7-8-20(25-24-19)29-13-16(26)12-21-10-9-15-5-6-17(27-3)18(11-15)28-4/h5-8,11,16,21,26H,9-10,12-13H2,1-4H3,(H,23,24)

HIDE SMILES / InChI

Molecular Formula	C20H29N5O4
Molecular Weight	403.4754
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://apps.who.int/iris/bitstream/handle/10665/275696/WHO-EMP-RHT-TSN-2013.1-eng.pdf | https://adisinsight.springer.com/drugs/800003234 | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 470, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ

Dramedilol is a beta-blocker with peripheral vasodilative activity. Dramedilol had been under investigation for the treatment of hypertension. However, this study was discontinued.

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:54:08 GMT 2023` Edited by `admin` on `Fri Dec 15 16:54:08 GMT 2023`
Record UNII	8PW276HX8U
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DRAMEDILOL

Official Name

English

ACETONE (±)-(6-(3-((3,4-DIMETHOXYPHENETHYL)AMINO)-2-HYDROXYPROPOXY)-3-PYRIDAZINYL)HYDRAZONE

Systematic Name

English

dramedilol [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29707