Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C21H25N3O |
| Molecular Weight | 335.4427 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=CC=C2OC(N[C@@H](CC3CCCCC3)C4=NC=CC=C4)=NC2=C1
InChI
InChIKey=RVXKHAITGKBBAC-SFHVURJKSA-N
InChI=1S/C21H25N3O/c1-15-10-11-20-19(13-15)24-21(25-20)23-18(17-9-5-6-12-22-17)14-16-7-3-2-4-8-16/h5-6,9-13,16,18H,2-4,7-8,14H2,1H3,(H,23,24)/t18-/m0/s1
| Molecular Formula | C21H25N3O |
| Molecular Weight | 335.4427 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Ontazolast (also known as BIRM 270) inhibits arachidonate release that blocks leukotriene B4 and platelet-activating factor biosynthesis in human neutrophils. This drug was studied for the treatment of asthma. In addition, was shown that ontazolast possessed potent class-III antiarrhythmic properties and induces prolongation of QTc in a dose-dependent fashion.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:36:35 GMT 2023
by
admin
on
Fri Dec 15 16:36:35 GMT 2023
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| Record UNII |
8P8TW6B25I
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| Record Status |
Validated (UNII)
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| Record Version |
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Code | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C29712
Created by
admin on Fri Dec 15 16:36:35 GMT 2023 , Edited by admin on Fri Dec 15 16:36:35 GMT 2023
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| Code System | Code | Type | Description | ||
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C79123
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CHEMBL2104845
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7267
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100000083340
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71458
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SUB09446MIG
Created by
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8P8TW6B25I
Created by
admin on Fri Dec 15 16:36:35 GMT 2023 , Edited by admin on Fri Dec 15 16:36:35 GMT 2023
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C090950
Created by
admin on Fri Dec 15 16:36:35 GMT 2023 , Edited by admin on Fri Dec 15 16:36:35 GMT 2023
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FF-69
Created by
admin on Fri Dec 15 16:36:35 GMT 2023 , Edited by admin on Fri Dec 15 16:36:35 GMT 2023
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147432-77-7
Created by
admin on Fri Dec 15 16:36:35 GMT 2023 , Edited by admin on Fri Dec 15 16:36:35 GMT 2023
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PRIMARY |
| Related Record | Type | Details | ||
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ACTIVE MOIETY |
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