Lasmecabtagene timgedleucel lentiviral vector

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Wed Apr 02 13:56:01 GMT 2025` Edited by `admin` on `Wed Apr 02 13:56:01 GMT 2025`
Source Materials Class	ORGANISM
Source Materials Type	RECOMBINANT VIRUS
Source Materials State	Self inactivating, non-replicating
Organism Family	Retroviridae
Organism Genus	Lentivirus
Organism Species	human immunodeficiency virus
Infraspecific Type	SUBSTRAIN
Infraspecific Name	(SIN)CD22CARrLV
Part	whole
Record UNII	8P4782A3C7
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Lasmecabtagene timgedleucel lentiviral vector

Common Name

English

Self inactivating, non-replicating lentiviral vector encoding a depletion ligand and a chimeric antigen receptor (CAR) targeting CD22 (Lasmecabtagene timgedleucel lentiviral vector)

Preferred Name

English

Code System Code Type Description

FDA UNII

8P4782A3C7

Created by admin on Wed Apr 02 13:56:01 GMT 2025 , Edited by admin on Wed Apr 02 13:56:01 GMT 2025

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Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
INSERTED GENE EXPRESSION VECTOR					Lasmecabtagene timgedleucel transgene insert encoding chimeric antigen receptor (CAR) targeting CD22	3HE99SAH65