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Details

Stereochemistry ACHIRAL
Molecular Formula C3H8N2S
Molecular Weight 104.174
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of N,N'-DIMETHYLTHIOUREA

SMILES

CNC(=S)NC

InChI

InChIKey=VLCDUOXHFNUCKK-UHFFFAOYSA-N
InChI=1S/C3H8N2S/c1-4-3(6)5-2/h1-2H3,(H2,4,5,6)

HIDE SMILES / InChI

Molecular Formula C3H8N2S
Molecular Weight 104.174
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Abscisic acid-induced hydrogen peroxide is required for anthocyanin accumulation in leaves of rice seedlings.
2008-08-25
Reactive oxygen species mediate detrusor overactivity via sensitization of afferent pathway in the bladder of anaesthetized rats.
2008-03
Hydroxyl radical scavenger ameliorates cisplatin-induced nephrotoxicity by preventing oxidative stress, redox state unbalance, impairment of energetic metabolism and apoptosis in rat kidney mitochondria.
2008-01
Dimethylthiourea protects against mitochondrial oxidative damage induced by cisplatin in liver of rats.
2007-12-15
The antioxidants dimethylsulfoxide and dimethylthiourea affect the immediate adhesion responses of larval haemocytes from 3 lepidopteran insect species.
2007-12
The participation of hydrogen peroxide in methyl jasmonate-induced NH(4)(+) accumulation in rice leaves.
2007-11
[Changes in H2O2 and salicylic acid contents as well as plasma membrane H+-ATPase activity and their relations in pea leaves during thermotolerance induction].
2007-10
S-allylcysteine scavenges singlet oxygen and hypochlorous acid and protects LLC-PK(1) cells of potassium dichromate-induced toxicity.
2007-10
Mechanisms of oxidant regulation of monocyte chemotactic protein 1 production in human whole blood and isolated mononuclear cells.
2007-08
Induction of cyclooxygenase-2 expression by manganese in cultured astrocytes.
2007-06
Immunoglobulin light chains generate hydrogen peroxide.
2007-04
[Upstream signaling pathway of neutrophil elastase-induced mucous hypersecretion].
2007-01-30
Induction of necrosis and apoptosis to KB cancer cells by sanguinarine is associated with reactive oxygen species production and mitochondrial membrane depolarization.
2007-01-15
Light-induced changes in protein nitration in photoreceptor rod outer segments.
2006-12-06
Puromycin aminonucleoside induces oxidant-dependent DNA damage in podocytes in vitro and in vivo.
2006-12
Isoflurane produces delayed preconditioning against spinal cord ischemic injury via release of free radicals in rabbits.
2006-11
Kinetics of Cisplatin and its monohydrated complex with sulfur-containing compounds designed for local otoprotective administration.
2006-11
Role of oxidative stress, mitochondrial membrane potential, and calcium homeostasis in nickel subsulfide-induced human lymphocyte death in vitro.
2006-10-01
Induction of glomerular heparanase expression in rats with adriamycin nephropathy is regulated by reactive oxygen species and the renin-angiotensin system.
2006-09
The effect of Euryale ferox (Makhana), an herb of aquatic origin, on myocardial ischemic reperfusion injury.
2006-09
Neural and hydroxyl radical mechanisms underlying laryngeal airway hyperreactivity induced by laryngeal acid-pepsin insult in anesthetized rats.
2006-07
A comparison of chemical systems for luminometric determination of antioxidant capacity towards individual reactive oxygen species.
2006-06-23
Induction of DNA double-strand breaks in A549 and normal human pulmonary epithelial cells by cigarette smoke is mediated by free radicals.
2006-06
Down-regulation of hepatic cytochrome P450 enzymes associated with cisplatin-induced acute renal failure in male rats.
2006-06
Light-induced exacerbation of retinal degeneration in a rat model of Smith-Lemli-Opitz syndrome.
2006-03
Expression and function of C/EBP homology protein (GADD153) in podocytes.
2006-01
Biochemical responses of the aquatic higher plant Lemna gibba to a mixture of copper and 1,2-dihydroxyanthraquinone: synergistic toxicity via reactive oxygen species.
2005-12
Normalizing renal reducing ability prevents adriamycin-induced proteinuria.
2005-11-11
Nickel compound-induced DNA single-strand breaks in chromosomal and nuclear chromatin in human blood lymphocytes in vitro: role of oxidative stress and intracellular calcium.
2005-10-03
Variability of biological effects of silicas: different degrees of activation of the fifth component of complement by amorphous silicas.
2005-10-01
Oxidant stress stimulates Ca2+-activated chloride channels in the apical activated membrane of cultured nonciliated human nasal epithelial cells.
2005-10
Role of oxidative stress, mitochondrial membrane potential, and calcium homeostasis in nickel sulfate-induced human lymphocyte death in vitro.
2005-09-10
Protective effect of a protein kinase inhibitor on cellular injury induced by cephaloridine in the porcine kidney cell line LLC-PK(1).
2005-08
Use of a stopped-flow technique for investigation and determination of thiourea and its N-methyl derivatives as inducers of the iodine-azide reaction.
2005-08
Signal pathway of cytokines produced by reactive oxygen species generated from phorbol myristate acetate-stimulated HMC-1 cells.
2005-07
Oxidation of a dimethylthiourea metabolite by iodine and acidified iodate: N,N'-dimethylaminoiminomethanesulfinic acid (1).
2005-07
p38 MAP kinase inhibition ameliorates cisplatin nephrotoxicity in mice.
2005-07
Pivotal role of gp91phox-containing NADH oxidase in lipopolysaccharide-induced tumor necrosis factor-alpha expression and myocardial depression.
2005-04-05
Kinetics and mechanism of the Co(II)-assisted oxidation of thioureas by dioxygen.
2005-03-21
Activation of porcine endothelium in response to xenogeneic serum causes thrombosis independently of platelet activation.
2005-03
Hydrogen peroxide is necessary for abscisic acid-induced senescence of rice leaves.
2004-12
The role of reactive oxygen species in microcystin-LR-induced DNA damage.
2004-07-15
Differential induction of heme oxygenase and other stress proteins in cultured hippocampal astrocytes and neurons by inorganic lead.
2004-07-01
Modulation of genotoxic effects in asbestos-exposed primary human mesothelial cells by radical scavengers, metal chelators and a glutathione precursor.
2004-04-11
Morphine modulates HIV-1 gp160-induced murine macrophage and human monocyte apoptosis by disparate ways.
2004-03
Superoxide, H2O2, and iron are required for TNF-alpha-induced MCP-1 gene expression in endothelial cells: role of Rac1 and NADPH oxidase.
2004-03
Role of chelate substituents and cis sigma-effect on the rate of ligand substitution at Pt(N-N-N) and Pt(N-N-C) centres.
2004-01-21
Photosensitized inactivation of T7 phage as surrogate of non-enveloped DNA viruses: efficiency and mechanism of action.
2003-12-05
Similar stress responses are elicited by copper and ultraviolet radiation in the aquatic plant Lemna gibba: implication of reactive oxygen species as common signals.
2003-12
Amelioration of glomerular injury in doxorubicin hydrochloride nephrosis by dimethylthiourea.
1991-11
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:44:02 GMT 2025
Edited
by admin
on Mon Mar 31 18:44:02 GMT 2025
Record UNII
8P30PMD17W
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NSC-8727
Preferred Name English
N,N'-DIMETHYLTHIOUREA
MI  
Systematic Name English
N,N'-DIMETHYLTHIOUREA [MI]
Common Name English
SYM-DIMETHYLTHIOUREA
Common Name English
THIOUREA, N,N'-DIMETHYL-
Systematic Name English
1,3-DIMETHYLTHIOUREA
Systematic Name English
UREA, 1,3-DIMETHYL-2-THIO-
Systematic Name English
Code System Code Type Description
MERCK INDEX
m4557
Created by admin on Mon Mar 31 18:44:02 GMT 2025 , Edited by admin on Mon Mar 31 18:44:02 GMT 2025
PRIMARY Merck Index
EPA CompTox
DTXSID2042191
Created by admin on Mon Mar 31 18:44:02 GMT 2025 , Edited by admin on Mon Mar 31 18:44:02 GMT 2025
PRIMARY
NSC
8727
Created by admin on Mon Mar 31 18:44:02 GMT 2025 , Edited by admin on Mon Mar 31 18:44:02 GMT 2025
PRIMARY
FDA UNII
8P30PMD17W
Created by admin on Mon Mar 31 18:44:02 GMT 2025 , Edited by admin on Mon Mar 31 18:44:02 GMT 2025
PRIMARY
ECHA (EC/EINECS)
208-588-2
Created by admin on Mon Mar 31 18:44:02 GMT 2025 , Edited by admin on Mon Mar 31 18:44:02 GMT 2025
PRIMARY
CAS
534-13-4
Created by admin on Mon Mar 31 18:44:02 GMT 2025 , Edited by admin on Mon Mar 31 18:44:02 GMT 2025
PRIMARY
PUBCHEM
2723631
Created by admin on Mon Mar 31 18:44:02 GMT 2025 , Edited by admin on Mon Mar 31 18:44:02 GMT 2025
PRIMARY