CLOMEGESTONE ACETATE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C24H31ClO4
Molecular Weight	418.954
Optical Activity	UNSPECIFIED
Defined Stereocenters	7 / 7
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]12C[C@@H](C)[C@](OC(C)=O)(C(C)=O)[C@@]1(C)CC[C@@]3([H])[C@@]2([H])C=C(Cl)C4=CC(=O)CC[C@]34C

InChI

InChIKey=WWSKHPDYSWDMNC-YRNSVOBJSA-N

InChI=1S/C24H31ClO4/c1-13-10-19-17-12-21(25)20-11-16(28)6-8-22(20,4)18(17)7-9-23(19,5)24(13,14(2)26)29-15(3)27/h11-13,17-19H,6-10H2,1-5H3/t13-,17-,18+,19+,22-,23+,24+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C24H31ClO4
Molecular Weight	418.954
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	7 / 7
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4406547 | https://www.sciencedirect.com/science/article/pii/S0039128X63801361

Clomegestone (clomagestone) is an investigational steroidal progestogen. Clomegestone exhibits anti-estrogenic activity in estrone stimulated immature mice when administered orally at 100 ug.

Approval Year

PubMed

Title	Date	PubMed
Glucose tolerance and serum insulin in rats and insulin sensitivity of rat adipose cells following treatment with the progestogen clomegestone acetate.	1974 Feb	4406547

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:17:17 GMT 2023` Edited by `admin` on `Fri Dec 15 17:17:17 GMT 2023`
Record UNII	8OIJ6341W7
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CLOMEGESTONE ACETATE

Official Name

English

6-Chloro-17-hydroxy-16α-methylpregna-4,6-diene-3,20-dione acetate

Common Name

English

SH-741

Code

English

CLOMEGESTONE ACETATE [USAN]

Common Name

English

PREGNA-4,6-DIENE-3,20-DIONE, 17-(ACETYLOXY)-6-CHLORO-16-METHYL-, (16.ALPHA.)-

Systematic Name

English

SH 741

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C776