CEFAZAFLUR SODIUM

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C13H12F3N6O4S3.Na
Molecular Weight	492.452
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Na+].[H][C@]12SCC(CSC3=NN=NN3C)=C(N1C(=O)[C@H]2NC(=O)CSC(F)(F)F)C([O-])=O

InChI

InChIKey=OTPDSOBPIAYYBT-YZUKSGEXSA-M

InChI=1S/C13H13F3N6O4S3.Na/c1-21-12(18-19-20-21)28-3-5-2-27-10-7(9(24)22(10)8(5)11(25)26)17-6(23)4-29-13(14,15)16;/h7,10H,2-4H2,1H3,(H,17,23)(H,25,26);/q;+1/p-1/t7-,10-;/m1./s1

HIDE SMILES / InChI

Molecular Formula	Na
Molecular Weight	22.9898
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C13H12F3N6O4S3
Molecular Weight	469.462
Charge	-1
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2569531 | https://www.ncbi.nlm.nih.gov/pubmed/313753 | https://www.ncbi.nlm.nih.gov/pubmed/26651 | https://www.ncbi.nlm.nih.gov/pubmed/924896

Cefazaflur (INN) is a semisynthetic first-generation cephalosporin antibiotic patented by Smithkline Corp. For treatment of bacterial infections.

Originator

Approval Year

PubMed

Title	Date	PubMed
In vitro studies with cefazaflur and other parenteral cephalosporins.	1977 Sep	924896

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:16:31 GMT 2023` Edited by `admin` on `Fri Dec 15 15:16:31 GMT 2023`
Record UNII	8NJ5RWV39D
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CEFAZAFLUR SODIUM

Official Name

English

5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID, 3-(((1-METHYL-1H-TETRAZOL-5-YL)THIO)METHYL)-8-OXO-7-((((TRIFLUOROMETHYL)THIO)ACETYL)AMINO)-, MONOSODIUM SALT (6R-TRANS)-

Common Name

English

CEFAZAFLUR SODIUM [USAN]

Common Name

English

SK&F 59962

Code

English

SK&F-59962

Code

English

Sodium (6R,7R)-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-7-[2-[(trifluoromethyl)thio]acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C357