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Details

Stereochemistry ACHIRAL
Molecular Formula NO3.Na
Molecular Weight 84.9947
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM NITRATE

SMILES

[Na+].[O-][N+]([O-])=O

InChI

InChIKey=VWDWKYIASSYTQR-UHFFFAOYSA-N
InChI=1S/NO3.Na/c2-1(3)4;/q-1;+1

HIDE SMILES / InChI

Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula NO3
Molecular Weight 62.0049
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Nitrate ion (NO3 −) is found naturally in the environment and is an important plant nutrient. It is present at varying concentrations in all plants and is a part of the nitrogen cycle. Nitrate probably has a role in protecting the gastrointestinal tract against a variety of gastrointestinal pathogens, as nitrous oxide and acidified nitrite have antibacterial properties. Significant bacterial reduction of nitrate to nitrite does not normally take place in the stomach, except in individuals with low gastric acidity or with gastrointestinal infections. These may include individuals using antacids, particularly those that block acid secretion. Potassium nitrate is used as mild local desensitizer in toothpastes.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
MAXIMUM STRENGTH SENSITIVE TRUE MINT

Approved Use

builds increasing protection against painful sensitivity of the teeth to cold, heat, acids, sweets, or contact; helps protect against cavities.

Launch Date

1.25176316E12
PubMed

PubMed

TitleDatePubMed
Acquired methemoglobinemia and hemolytic anemia after usual doses of phenazopyridine.
1982 Feb
[Acute and chronic cardiac decompensation: is vasodilator therapy useful?].
1982 Jan 14
Nitrates in acute myocardial infarction.
1987
Dipyridamole enhances interleukin-1beta-stimulated nitric oxide production by cultured rat vascular smooth muscle cells.
1996 Feb 5
Therapy of angina pectoris with long-acting nitrates: which agent and when?
1996 May
The assimilatory nitrate reductase from the phototrophic bacterium, Rhodobacter capsulatus E1F1, is a flavoprotein.
1997 Sep 1
Diltiazem-mediated inhibition of sildenafil metabolism may promote nitrate-induced hypotension.
2000 Oct
Respiratory tract responses to repeated inhalation of an oxidant and acid gas-particle air pollutant mixture.
2001 Jun
Successful DTPA therapy in the case of 239Pu penetration via injured skin exposed to nitric acid.
2003
Raised nitrate concentration and low SOD activity in the CSF of sporadic ALS patients.
2003 May
Adrenomedullin contributes to vascular hyporeactivity in cirrhotic rats with ascites via a release of nitric oxide.
2004 Jul
Nitrification by plants that also fix nitrogen.
2004 Jul 1
Novel regulation of cystic fibrosis transmembrane conductance regulator (CFTR) channel gating by external chloride.
2004 Oct 1
Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V, and IX with anions isosteric and isoelectronic with sulfate, nitrate, and carbonate.
2005 Feb 1
Role of tumor necrosis factor-alpha in down-regulation of hepatic cytochrome P450 and P-glycoprotein by endotoxin.
2005 Jan 10
Evaluation of possible goitrogenic and anti-thyroidal effect of nitrate, a potential environmental pollutant.
2005 Jul-Sep
Cl- interference with the epithelial Na+ channel ENaC.
2005 Sep 9
Immune cell infiltration and broncovascular remodeling after nitric acid nasal instillation in a mouse bronchiolitis obliterans model.
2006 Jul-Aug
Modifications of inflammatory pathways in rat intestine following chronic ingestion of depleted uranium.
2007 Aug
The nitric acid burn trauma of the skin.
2010 Apr
Relationship between endogenous concentrations of vasoactive substances and measures of peripheral vasodilator function in patients with coronary artery disease.
2010 Jan
Fine particulate matter constituents and cardiopulmonary mortality in a heavily polluted Chinese city.
2012 Mar
Patents
Substance Class Chemical
Created
by admin
on Wed Jul 05 23:01:30 UTC 2023
Edited
by admin
on Wed Jul 05 23:01:30 UTC 2023
Record UNII
8M4L3H2ZVZ
Record Status Validated (UNII)
Record Version
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Name Type Language
SODIUM NITRATE
FCC   HSDB   II   INCI   MART.   MI   VANDF   WHO-DD  
INCI  
Official Name English
INS NO.251
Code English
SODIUM NITRATE [MART.]
Common Name English
SODIUM NITRATE [II]
Common Name English
NSC-77390
Code English
INS-251
Code English
SODIUM NITRATE [VANDF]
Common Name English
SODIUM NITRATE [FCC]
Common Name English
SODIUM NITRATE [MI]
Common Name English
NATRUM NITRICUM
HPUS  
Common Name English
NATRUM NITRICUM [HPUS]
Common Name English
CUBIC NITER
Common Name English
CHILE SALTPETER
Common Name English
NITRIC ACID SODIUM SALT (1:1)
Common Name English
Sodium nitrate [WHO-DD]
Common Name English
SODA NITER
Common Name English
SODIUM NITRATE [INCI]
Common Name English
SODIUM NITRATE [HSDB]
Common Name English
E-251
Code English
Classification Tree Code System Code
JECFA EVALUATION INS-251
Created by admin on Wed Jul 05 23:01:30 UTC 2023 , Edited by admin on Wed Jul 05 23:01:30 UTC 2023
DSLD 3148 (Number of products:16)
Created by admin on Wed Jul 05 23:01:30 UTC 2023 , Edited by admin on Wed Jul 05 23:01:30 UTC 2023
EPA PESTICIDE CODE 76104
Created by admin on Wed Jul 05 23:01:30 UTC 2023 , Edited by admin on Wed Jul 05 23:01:30 UTC 2023
CFR 21 CFR 172.170
Created by admin on Wed Jul 05 23:01:30 UTC 2023 , Edited by admin on Wed Jul 05 23:01:30 UTC 2023
CODEX ALIMENTARIUS (GSFA) INS-251
Created by admin on Wed Jul 05 23:01:30 UTC 2023 , Edited by admin on Wed Jul 05 23:01:30 UTC 2023
Food Contact Sustance Notif, (FCN No.) FCN NO. 569
Created by admin on Wed Jul 05 23:01:30 UTC 2023 , Edited by admin on Wed Jul 05 23:01:30 UTC 2023
Code System Code Type Description
WIKIPEDIA
SODIUM NITRATE
Created by admin on Wed Jul 05 23:01:30 UTC 2023 , Edited by admin on Wed Jul 05 23:01:30 UTC 2023
PRIMARY
MERCK INDEX
M10048
Created by admin on Wed Jul 05 23:01:30 UTC 2023 , Edited by admin on Wed Jul 05 23:01:30 UTC 2023
PRIMARY Merck Index
NSC
77390
Created by admin on Wed Jul 05 23:01:30 UTC 2023 , Edited by admin on Wed Jul 05 23:01:30 UTC 2023
PRIMARY
MESH
C031618
Created by admin on Wed Jul 05 23:01:30 UTC 2023 , Edited by admin on Wed Jul 05 23:01:30 UTC 2023
PRIMARY
PUBCHEM
24268
Created by admin on Wed Jul 05 23:01:30 UTC 2023 , Edited by admin on Wed Jul 05 23:01:30 UTC 2023
PRIMARY
CHEBI
63005
Created by admin on Wed Jul 05 23:01:30 UTC 2023 , Edited by admin on Wed Jul 05 23:01:30 UTC 2023
PRIMARY
NCI_THESAURUS
C84161
Created by admin on Wed Jul 05 23:01:30 UTC 2023 , Edited by admin on Wed Jul 05 23:01:30 UTC 2023
PRIMARY
JECFA MONOGRAPH
INS-251
Created by admin on Wed Jul 05 23:01:30 UTC 2023 , Edited by admin on Wed Jul 05 23:01:30 UTC 2023
PRIMARY
FDA UNII
8M4L3H2ZVZ
Created by admin on Wed Jul 05 23:01:30 UTC 2023 , Edited by admin on Wed Jul 05 23:01:30 UTC 2023
PRIMARY
RXCUI
36700
Created by admin on Wed Jul 05 23:01:30 UTC 2023 , Edited by admin on Wed Jul 05 23:01:30 UTC 2023
PRIMARY RxNorm
EPA CompTox
DTXSID6020937
Created by admin on Wed Jul 05 23:01:30 UTC 2023 , Edited by admin on Wed Jul 05 23:01:30 UTC 2023
PRIMARY
NCI_THESAURUS
C45678
Created by admin on Wed Jul 05 23:01:30 UTC 2023 , Edited by admin on Wed Jul 05 23:01:30 UTC 2023
CONCEPT Industrial Aid
EVMPD
SUB15307MIG
Created by admin on Wed Jul 05 23:01:30 UTC 2023 , Edited by admin on Wed Jul 05 23:01:30 UTC 2023
PRIMARY
ECHA (EC/EINECS)
231-554-3
Created by admin on Wed Jul 05 23:01:30 UTC 2023 , Edited by admin on Wed Jul 05 23:01:30 UTC 2023
PRIMARY
DAILYMED
8M4L3H2ZVZ
Created by admin on Wed Jul 05 23:01:30 UTC 2023 , Edited by admin on Wed Jul 05 23:01:30 UTC 2023
PRIMARY
CAS
7631-99-4
Created by admin on Wed Jul 05 23:01:30 UTC 2023 , Edited by admin on Wed Jul 05 23:01:30 UTC 2023
PRIMARY
HSDB
726
Created by admin on Wed Jul 05 23:01:30 UTC 2023 , Edited by admin on Wed Jul 05 23:01:30 UTC 2023
PRIMARY
SMS_ID
100000078137
Created by admin on Wed Jul 05 23:01:30 UTC 2023 , Edited by admin on Wed Jul 05 23:01:30 UTC 2023
PRIMARY
RS_ITEM_NUM
1614432
Created by admin on Wed Jul 05 23:01:30 UTC 2023 , Edited by admin on Wed Jul 05 23:01:30 UTC 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY