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Details

Stereochemistry ACHIRAL
Molecular Formula NO3.Na
Molecular Weight 84.9947
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM NITRATE

SMILES

[Na+].[O-][N+]([O-])=O

InChI

InChIKey=VWDWKYIASSYTQR-UHFFFAOYSA-N
InChI=1S/NO3.Na/c2-1(3)4;/q-1;+1

HIDE SMILES / InChI

Molecular Formula NO3
Molecular Weight 62.0049
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Nitrate ion (NO3 −) is found naturally in the environment and is an important plant nutrient. It is present at varying concentrations in all plants and is a part of the nitrogen cycle. Nitrate probably has a role in protecting the gastrointestinal tract against a variety of gastrointestinal pathogens, as nitrous oxide and acidified nitrite have antibacterial properties. Significant bacterial reduction of nitrate to nitrite does not normally take place in the stomach, except in individuals with low gastric acidity or with gastrointestinal infections. These may include individuals using antacids, particularly those that block acid secretion. Potassium nitrate is used as mild local desensitizer in toothpastes.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
MAXIMUM STRENGTH SENSITIVE TRUE MINT

Approved Use

builds increasing protection against painful sensitivity of the teeth to cold, heat, acids, sweets, or contact; helps protect against cavities.

Launch Date

1.25176316E12
PubMed

PubMed

TitleDatePubMed
Nitrate reductase from Achromobacter fischeri; purification and properties: function of flavines and cytochrome.
1957 Mar
Proton translocation and the respiratory nitrate reductase of Escherichia coli.
1975 Dec
Electrophysiologic properties of hydralazine in man.
1980 Sep
Calcium antagonists.
1985
Nitrates in acute myocardial infarction.
1987
The assimilatory nitrate reductase from the phototrophic bacterium, Rhodobacter capsulatus E1F1, is a flavoprotein.
1997 Sep 1
Diltiazem-mediated inhibition of sildenafil metabolism may promote nitrate-induced hypotension.
2000 Oct
Biphasic alterations in gastrointestinal transit following endotoxaemia in mice.
2001 Dec
Municipal drinking water nitrate level and cancer risk in older women: the Iowa Women's Health Study.
2001 May
Raised nitrate concentration and low SOD activity in the CSF of sporadic ALS patients.
2003 May
Nitrification by plants that also fix nitrogen.
2004 Jul 1
Rate and extent of percutaneous absorption of sertaconazole nitrate after topical administration.
2005
Methods of quantitative analysis of the nitric oxide metabolites nitrite and nitrate in human biological fluids.
2005 Aug
[Clinical observation on acupuncture combined with medication for intractable angina pectoris].
2005 Feb
Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V, and IX with anions isosteric and isoelectronic with sulfate, nitrate, and carbonate.
2005 Feb 1
Nitric acid-induced bronchiolitis in rats mimics childhood Bronchiolitis obliterans.
2005 Nov-Dec
Clinical diagnostic indicators of renal and bone damage in rats intramuscularly injected with depleted uranium.
2006
Immune cell infiltration and broncovascular remodeling after nitric acid nasal instillation in a mouse bronchiolitis obliterans model.
2006 Jul-Aug
Oxidative and nitrosative stress in acute ischaemic stroke.
2007 Jan
Water disinfection by-products and pre-labor rupture of membranes.
2008 Sep 1
The nitric acid burn trauma of the skin.
2010 Apr
Goitrogenic anions, thyroid-stimulating hormone, and thyroid hormone in infants.
2010 Sep
Reduced systemic vascular resistance in healthy volunteers with presyncopal symptoms during a nitrate-stimulated tilt-table test.
2011 Jan
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 16 17:21:29 UTC 2022
Edited
by admin
on Fri Dec 16 17:21:29 UTC 2022
Record UNII
8M4L3H2ZVZ
Record Status Validated (UNII)
Record Version
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Name Type Language
SODIUM NITRATE
FCC   HSDB   II   INCI   MART.   MI   VANDF   WHO-DD  
INCI  
Official Name English
INS NO.251
Code English
SODIUM NITRATE [MART.]
Common Name English
SODIUM NITRATE [II]
Common Name English
NSC-77390
Code English
INS-251
Code English
SODIUM NITRATE [VANDF]
Common Name English
SODIUM NITRATE [FCC]
Common Name English
SODIUM NITRATE [MI]
Common Name English
NATRUM NITRICUM
HPUS  
Common Name English
NATRUM NITRICUM [HPUS]
Common Name English
CUBIC NITER
Common Name English
CHILE SALTPETER
Common Name English
NITRIC ACID SODIUM SALT (1:1)
Common Name English
Sodium nitrate [WHO-DD]
Common Name English
SODA NITER
Common Name English
SODIUM NITRATE [INCI]
Common Name English
SODIUM NITRATE [HSDB]
Common Name English
E-251
Code English
Classification Tree Code System Code
JECFA EVALUATION INS-251
Created by admin on Fri Dec 16 17:21:29 UTC 2022 , Edited by admin on Fri Dec 16 17:21:29 UTC 2022
DSLD 3148 (Number of products:16)
Created by admin on Fri Dec 16 17:21:29 UTC 2022 , Edited by admin on Fri Dec 16 17:21:29 UTC 2022
EPA PESTICIDE CODE 76104
Created by admin on Fri Dec 16 17:21:29 UTC 2022 , Edited by admin on Fri Dec 16 17:21:29 UTC 2022
CFR 21 CFR 172.170
Created by admin on Fri Dec 16 17:21:29 UTC 2022 , Edited by admin on Fri Dec 16 17:21:29 UTC 2022
CODEX ALIMENTARIUS (GSFA) INS-251
Created by admin on Fri Dec 16 17:21:29 UTC 2022 , Edited by admin on Fri Dec 16 17:21:29 UTC 2022
Food Contact Sustance Notif, (FCN No.) FCN NO. 569
Created by admin on Fri Dec 16 17:21:29 UTC 2022 , Edited by admin on Fri Dec 16 17:21:29 UTC 2022
Code System Code Type Description
WIKIPEDIA
SODIUM NITRATE
Created by admin on Fri Dec 16 17:21:29 UTC 2022 , Edited by admin on Fri Dec 16 17:21:29 UTC 2022
PRIMARY
MERCK INDEX
M10048
Created by admin on Fri Dec 16 17:21:29 UTC 2022 , Edited by admin on Fri Dec 16 17:21:29 UTC 2022
PRIMARY Merck Index
NSC
77390
Created by admin on Fri Dec 16 17:21:29 UTC 2022 , Edited by admin on Fri Dec 16 17:21:29 UTC 2022
PRIMARY
MESH
C031618
Created by admin on Fri Dec 16 17:21:29 UTC 2022 , Edited by admin on Fri Dec 16 17:21:29 UTC 2022
PRIMARY
PUBCHEM
24268
Created by admin on Fri Dec 16 17:21:29 UTC 2022 , Edited by admin on Fri Dec 16 17:21:29 UTC 2022
PRIMARY
CHEBI
63005
Created by admin on Fri Dec 16 17:21:29 UTC 2022 , Edited by admin on Fri Dec 16 17:21:29 UTC 2022
PRIMARY
NCI_THESAURUS
C84161
Created by admin on Fri Dec 16 17:21:29 UTC 2022 , Edited by admin on Fri Dec 16 17:21:29 UTC 2022
PRIMARY
JECFA MONOGRAPH
INS-251
Created by admin on Fri Dec 16 17:21:29 UTC 2022 , Edited by admin on Fri Dec 16 17:21:29 UTC 2022
PRIMARY
FDA UNII
8M4L3H2ZVZ
Created by admin on Fri Dec 16 17:21:29 UTC 2022 , Edited by admin on Fri Dec 16 17:21:29 UTC 2022
PRIMARY
RXCUI
36700
Created by admin on Fri Dec 16 17:21:29 UTC 2022 , Edited by admin on Fri Dec 16 17:21:29 UTC 2022
PRIMARY RxNorm
EPA CompTox
DTXSID6020937
Created by admin on Fri Dec 16 17:21:29 UTC 2022 , Edited by admin on Fri Dec 16 17:21:29 UTC 2022
PRIMARY
NCI_THESAURUS
C45678
Created by admin on Fri Dec 16 17:21:29 UTC 2022 , Edited by admin on Fri Dec 16 17:21:29 UTC 2022
CONCEPT Industrial Aid
EVMPD
SUB15307MIG
Created by admin on Fri Dec 16 17:21:29 UTC 2022 , Edited by admin on Fri Dec 16 17:21:29 UTC 2022
PRIMARY
ECHA (EC/EINECS)
231-554-3
Created by admin on Fri Dec 16 17:21:29 UTC 2022 , Edited by admin on Fri Dec 16 17:21:29 UTC 2022
PRIMARY
DAILYMED
8M4L3H2ZVZ
Created by admin on Fri Dec 16 17:21:29 UTC 2022 , Edited by admin on Fri Dec 16 17:21:29 UTC 2022
PRIMARY
CAS
7631-99-4
Created by admin on Fri Dec 16 17:21:29 UTC 2022 , Edited by admin on Fri Dec 16 17:21:29 UTC 2022
PRIMARY
HSDB
726
Created by admin on Fri Dec 16 17:21:29 UTC 2022 , Edited by admin on Fri Dec 16 17:21:29 UTC 2022
PRIMARY
RS_ITEM_NUM
1614432
Created by admin on Fri Dec 16 17:21:29 UTC 2022 , Edited by admin on Fri Dec 16 17:21:29 UTC 2022
PRIMARY
Related Record Type Details
ACTIVE MOIETY