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Details

Stereochemistry ACHIRAL
Molecular Formula NO3.Na
Molecular Weight 84.9947
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM NITRATE

SMILES

[Na+].[O-][N+]([O-])=O

InChI

InChIKey=VWDWKYIASSYTQR-UHFFFAOYSA-N
InChI=1S/NO3.Na/c2-1(3)4;/q-1;+1

HIDE SMILES / InChI
Molecular Formula NO3
Molecular Weight 62.0049
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula Na
Molecular Weight 22.98976928
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Nitrate ion (NO3 −) is found naturally in the environment and is an important plant nutrient. It is present at varying concentrations in all plants and is a part of the nitrogen cycle. Nitrate probably has a role in protecting the gastrointestinal tract against a variety of gastrointestinal pathogens, as nitrous oxide and acidified nitrite have antibacterial properties. Significant bacterial reduction of nitrate to nitrite does not normally take place in the stomach, except in individuals with low gastric acidity or with gastrointestinal infections. These may include individuals using antacids, particularly those that block acid secretion. Potassium nitrate is used as mild local desensitizer in toothpastes.

Approval Year

1921
1468
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
Not Provided
511
MAXIMUM STRENGTH SENSITIVE TRUE MINT

Approved Use

builds increasing protection against painful sensitivity of the teeth to cold, heat, acids, sweets, or contact; helps protect against cavities.

Launch Date

2009
PubMed

PubMed

TitleDatePubMed
NOS2 is critical to the development of emphysema in Sftpd deficient mice but does not affect surfactant homeostasis.
2014
Fine particulate matter constituents and cardiopulmonary mortality in a heavily polluted Chinese city.
2012-03
Reduced systemic vascular resistance in healthy volunteers with presyncopal symptoms during a nitrate-stimulated tilt-table test.
2011-01
Goitrogenic anions, thyroid-stimulating hormone, and thyroid hormone in infants.
2010-09
Fatal pulmonary edema after acute occupational exposure to nitric acid.
2010-07
The nitric acid burn trauma of the skin.
2010-04
Relationship between endogenous concentrations of vasoactive substances and measures of peripheral vasodilator function in patients with coronary artery disease.
2010-01
Management of unusually extensive esophagogastric corrosive injuries: emergency measures and gastric reconstruction.
2009-05
Acute lung injury after inhalation of nitric acid.
2008-12
An unusual circumstance of internal chemical burn injury - a case report.
2008-10
Water disinfection by-products and pre-labor rupture of membranes.
2008-09-01
Free copper, ferroxidase and SOD1 activities, lipid peroxidation and NO(x) content in the CSF. A different marker profile in four neurodegenerative diseases.
2008-09
Synthesis, pharmacological activity and nitric oxide generation by nitrate derivatives of theophylline.
2008-05
Successful extracorporeal life support after potentially fatal pulmonary oedema caused by inhalation of nitric and hydrofluoric acid fumes.
2007-10
Modifications of inflammatory pathways in rat intestine following chronic ingestion of depleted uranium.
2007-08
Oxidative and nitrosative stress in acute ischaemic stroke.
2007-01
Serofendic acid, a substance extracted from fetal calf serum, as a novel drug for cardioprotection.
2007
Blockade of endothelin ET(A)/ET(B) receptors favors a role for endothelin during acute Trypanosoma cruzi infection in rats.
2006-07
Evaluation of possible goitrogenic and anti-thyroidal effect of nitrate, a potential environmental pollutant.
2006-01-31
Immune cell infiltration and broncovascular remodeling after nitric acid nasal instillation in a mouse bronchiolitis obliterans model.
2006-01-07
Clinical diagnostic indicators of renal and bone damage in rats intramuscularly injected with depleted uranium.
2006
Cl- interference with the epithelial Na+ channel ENaC.
2005-09-09
Methods of quantitative analysis of the nitric oxide metabolites nitrite and nitrate in human biological fluids.
2005-08
Carbonic anhydrase inhibitors. Inhibition of isozymes I, II, IV, V, and IX with anions isosteric and isoelectronic with sulfate, nitrate, and carbonate.
2005-02-01
[Clinical observation on acupuncture combined with medication for intractable angina pectoris].
2005-02
Role of tumor necrosis factor-alpha in down-regulation of hepatic cytochrome P450 and P-glycoprotein by endotoxin.
2005-01-10
Rate and extent of percutaneous absorption of sertaconazole nitrate after topical administration.
2005
Epidemiology of 377 patients with chemical burns in Guangdong province.
2004-09
Nitric acid-induced bronchiolitis in rats mimics childhood Bronchiolitis obliterans.
2004-08-12
Acute gastric perforation after acid ingestion.
2002-09
Respiratory tract responses to repeated inhalation of an oxidant and acid gas-particle air pollutant mixture.
2001-06
[Upper gastrointestinal tract injury caused by ingestion of caustic substances].
2001-04
Atrial natriuretic peptide and oxytocin induce natriuresis by release of cGMP.
1999-01-05
The assimilatory nitrate reductase from the phototrophic bacterium, Rhodobacter capsulatus E1F1, is a flavoprotein.
1997-09-01
Serum and tissue nitrate levels in murine visceral leishmaniasis correlate with parasite load but not with host protection.
1997-07-01
Incidence of childhood diabetes mellitus in Yorkshire, northern England, is associated with nitrate in drinking water: an ecological analysis.
1997-05
Prevention by morphine of apomorphine- and oxytocin-induced penile erection and yawning: involvement of nitric oxide.
1997-05
Therapy of angina pectoris with long-acting nitrates: which agent and when?
1996-05
Dipyridamole enhances interleukin-1beta-stimulated nitric oxide production by cultured rat vascular smooth muscle cells.
1996-02-05
Transient reversal of blood flow in an internal thoracic artery to coronary artery graft during syncope.
1994-08
[Anti-angina therapy of coronary heart disease. Mono- or combination treatment].
1991-05
[Drug treatment of myocardial ischemia].
1991
Nitrates in acute myocardial infarction.
1987
Drug-induced torsade de pointes.
1985-11-01
Addition of nifedipine to maximal nitrate and beta-adrenoreceptor blocker therapy in coronary artery disease.
1985-05-01
Calcium antagonists.
1985
Acquired methemoglobinemia and hemolytic anemia after usual doses of phenazopyridine.
1982-02
[Acute and chronic cardiac decompensation: is vasodilator therapy useful?].
1982-01-14
Electrophysiologic properties of hydralazine in man.
1980-09
Proton translocation and the respiratory nitrate reductase of Escherichia coli.
1975-12
Patents

Patents

03931177
6
03957791
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03973039
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03978092
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03987186
7
03988268
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03992446
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03994968
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04005219
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04010201
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04021479
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04036838
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04038405
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04049705
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04053479
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04055411
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04066651
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04066830
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04067993
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04071524
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04093446
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04096337
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04107315
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04118461
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04120899
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04126444
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04136192
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04141990
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04154941
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04159273
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04166119
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04174342
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04174397
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04177057
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04178387
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04180572
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04180679
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04196120
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04199586
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04200640
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04279918
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04415752
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04555386
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04604267
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04652559
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05292387
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05300511
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05616586
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05633248
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05739129
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05965679
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05972136
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06531502
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06972286
6
07029504
8
07495021
32
08106064
6
08394837
6
08629277
6
08735322
6
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:00:11 GMT 2025
Edited
by admin
on Mon Mar 31 18:00:11 GMT 2025
Record UNII
8M4L3H2ZVZ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SODIUM NITRATE
FCC   HSDB   II   INCI   MART.   MI   VANDF   WHO-DD  
INCI  
Official Name English
NATRUM NITRICUM
HPUS  
Preferred Name English
INS NO.251
Code English
SODIUM NITRATE [MART.]
Common Name English
SODIUM NITRATE [II]
Common Name English
NSC-77390
Code English
INS-251
Code English
SODIUM NITRATE [VANDF]
Common Name English
SODIUM NITRATE [FCC]
Common Name English
SODIUM NITRATE [MI]
Common Name English
NATRUM NITRICUM [HPUS]
Common Name English
CUBIC NITER
Common Name English
CHILE SALTPETER
Common Name English
NITRIC ACID SODIUM SALT (1:1)
Common Name English
Sodium nitrate [WHO-DD]
Common Name English
SODA NITER
Common Name English
SODIUM NITRATE [HSDB]
Common Name English
E-251
Code English
Classification Tree Code System Code
JECFA EVALUATION INS-251
Created by admin on Mon Mar 31 18:00:11 GMT 2025 , Edited by admin on Mon Mar 31 18:00:11 GMT 2025
DSLD 3148 (Number of products:16)
Created by admin on Mon Mar 31 18:00:11 GMT 2025 , Edited by admin on Mon Mar 31 18:00:11 GMT 2025
EPA PESTICIDE CODE 76104
Created by admin on Mon Mar 31 18:00:11 GMT 2025 , Edited by admin on Mon Mar 31 18:00:11 GMT 2025
CFR 21 CFR 172.170
Created by admin on Mon Mar 31 18:00:11 GMT 2025 , Edited by admin on Mon Mar 31 18:00:11 GMT 2025
CODEX ALIMENTARIUS (GSFA) INS-251
Created by admin on Mon Mar 31 18:00:11 GMT 2025 , Edited by admin on Mon Mar 31 18:00:11 GMT 2025
Food Contact Sustance Notif, (FCN No.) FCN NO. 569
Created by admin on Mon Mar 31 18:00:11 GMT 2025 , Edited by admin on Mon Mar 31 18:00:11 GMT 2025
Code System Code Type Description
WIKIPEDIA
SODIUM NITRATE
Created by admin on Mon Mar 31 18:00:11 GMT 2025 , Edited by admin on Mon Mar 31 18:00:11 GMT 2025
PRIMARY
MERCK INDEX
m10048
Created by admin on Mon Mar 31 18:00:11 GMT 2025 , Edited by admin on Mon Mar 31 18:00:11 GMT 2025
PRIMARY Merck Index
NSC
77390
Created by admin on Mon Mar 31 18:00:11 GMT 2025 , Edited by admin on Mon Mar 31 18:00:11 GMT 2025
PRIMARY
MESH
C031618
Created by admin on Mon Mar 31 18:00:11 GMT 2025 , Edited by admin on Mon Mar 31 18:00:11 GMT 2025
PRIMARY
PUBCHEM
24268
Created by admin on Mon Mar 31 18:00:11 GMT 2025 , Edited by admin on Mon Mar 31 18:00:11 GMT 2025
PRIMARY
CHEBI
63005
Created by admin on Mon Mar 31 18:00:11 GMT 2025 , Edited by admin on Mon Mar 31 18:00:11 GMT 2025
PRIMARY
NCI_THESAURUS
C84161
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PRIMARY
FDA UNII
8M4L3H2ZVZ
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PRIMARY
RXCUI
36700
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PRIMARY RxNorm
EPA CompTox
DTXSID6020937
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PRIMARY
NCI_THESAURUS
C45678
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CONCEPT Industrial Aid
EVMPD
SUB15307MIG
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PRIMARY
ECHA (EC/EINECS)
231-554-3
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PRIMARY
DAILYMED
8M4L3H2ZVZ
Created by admin on Mon Mar 31 18:00:11 GMT 2025 , Edited by admin on Mon Mar 31 18:00:11 GMT 2025
PRIMARY
CAS
7631-99-4
Created by admin on Mon Mar 31 18:00:11 GMT 2025 , Edited by admin on Mon Mar 31 18:00:11 GMT 2025
PRIMARY
HSDB
726
Created by admin on Mon Mar 31 18:00:11 GMT 2025 , Edited by admin on Mon Mar 31 18:00:11 GMT 2025
PRIMARY
SMS_ID
100000078137
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PRIMARY
RS_ITEM_NUM
1614432
Created by admin on Mon Mar 31 18:00:11 GMT 2025 , Edited by admin on Mon Mar 31 18:00:11 GMT 2025
PRIMARY
Related Record Type Details
Structure of NITRATE ION
ACTIVE MOIETY
NIH
NCATS
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