Cugrastomig

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 20:58:42 GMT 2025` Edited by `admin` on `Wed Apr 02 20:58:42 GMT 2025`
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type	IGG1\|LAMDA
Sequence Origin	HUMANIZED MOUSE
Record UNII	8JU4Y2PP36
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Cugrastomig

Official Name

English

H-gamma1 heavy chain anti-LAG3 fused to a scFv anti-PDCD1 (1-716) [ Hgamma1 heavy chain anti-LAG3 Homo sapiens (1-450) [VH (Homo sapiens IGHV4-34*01 (90.6%) -(IGHD) -IGHJ5*02 (93.8%), CDR-IMGT [8.7.14] (26-33.51-57.96-109)) (1-120)-Homo sapiens IGHG1*01,

Preferred Name

English

Immunoglobulin G1 [237-alanine,238-alanine,240-alanine], bispecific, anti-(human lymphocyte activation gene-3 protein) (human-Mus musculus monoclonal AK129 ?1-chain) fusion protein with peptide linker ((GGGGS)4) fusion protein with immunoglobulin anti-(h

Common Name

English

immunoglobulin IG fused to 2 scFv (H-gamma1-scFvhk_L'-kappa) dimer bisdisulfide, anti-[Homo sapiens LAG3 (lymphocyte activating 3, lymphocyteactivation 3, CD223)] and scFv anti-[Homo sapiens PDCD1 (programmed cell death 1, PD-1, PD1, CD279)], Homo sapien

Common Name

English

cugrastomig [INN]

Common Name

English

Code System Code Type Description

INN

12924