FLURETOFEN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H9F
Molecular Weight	196.2197
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

FC1=C(C=CC=C1)C2=CC=C(C=C2)C#C

InChI

InChIKey=YETULFFXNIHQLK-UHFFFAOYSA-N

InChI=1S/C14H9F/c1-2-11-7-9-12(10-8-11)13-5-3-4-6-14(13)15/h1,3-10H

HIDE SMILES / InChI

Molecular Formula	C14H9F
Molecular Weight	196.2197
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/38077

There is no information about biological and pharmacological application of Fluretofen also known as 4'-ethynyl-2-fluorobiphenyl. It is known, that it is an anti-inflammatory agent. And its main metabolite 2-fluoro-4'-biphenylyl)acetic acid, also possesses anti-inflammatory activity.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
Biotransformation of 4'-ethynl-2-fluorobiphenyl in the rat. In vitro and in vivo studies.	1979 Mar-Apr	38077
Deuterium-isotope effect in the biotransformation of 4-ethynylbiphenyls to 4-biphenylylacetic acids by rat hepatic microsomes.	1981 Mar 31	7236291

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:16:52 UTC 2023` Edited by `admin` on `Fri Dec 15 15:16:52 UTC 2023`
Record UNII	8IN4W55F02
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FLURETOFEN

Official Name

English

1,1'-BIPHENYL, 4'-ETHYNYL-2-FLUORO-

Systematic Name

English

fluretofen [INN]

Common Name

English

FLURETOFEN [USAN]

Common Name

English

COMPOUND-93819

Code

English

COMPOUND 93819

Code

English

Code System Code Type Description

FDA UNII

8IN4W55F02