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Description

Technetium (99mTc) tilmanocept, trade name Lymphoseek, is a radiopharmaceutical diagnostic imaging agent approved for the imaging of lymph nodes. It is used to locate those lymph nodes which may be draining from tumors, and assist doctors in locating those lymph nodes for removal during surgery.

Originator

Approval Year

Targets

Primary TargetPharmacologyConditionPotency
27.6 pM [Kd]

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
LYMPHOSEEK
Diagnostic
LYMPHOSEEK
Diagnostic
LYMPHOSEEK

PubMed

Sample Use Guides

In Vivo Use Guide
Administer 18.5 MBq (0.5 mCi) of Lymphoseek at least 15 minutes before initiating intraoperative lymphatic mapping. Complete lymphatic mapping within 15 hours of Lymphoseek injection. Recommended administration routes are intradermal, subcutaneous, and peritumoral injections. Each radiolabled Lymphoseek vial contains sufficient amount to provide doses for up to four patients when prepared according to the instructions. The radiolabeled Lymphoseek is to be used within 6 hours of its preparation.
Route of Administration: Other
In Vitro Use Guide
Unknown
Substance Class Polymer
Record UNII
8IHI69PQTC
Record Status Validated (UNII)
Record Version

Structural Modifications