2-FURAMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C5H5NO2
Molecular Weight	111.0987
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC(=O)C1=CC=CO1

InChI

InChIKey=TVFIYRKPCACCNL-UHFFFAOYSA-N

InChI=1S/C5H5NO2/c6-5(7)4-2-1-3-8-4/h1-3H,(H2,6,7)

HIDE SMILES / InChI

Molecular Formula	C5H5NO2
Molecular Weight	111.0987
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6729814

2-Furamide is a toxic furan derivative. Intraperitoneal administration to mice at causes significant liver damage observed as centrilobular necrosis at doses 1.4-2.6 mmol/kg in mice.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2596

PubMed

Title	Date	PubMed
Toxicity-distribution relationships among 3-alkylfurans in mouse liver and kidney.	1984-06-15	6729814
Renal and hepatic necrosis after metabolic activation of 2-substituted furans and thiophenes, including furosemide and cephaloridine.	1977-11	595008

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:08:22 GMT 2025` Edited by `admin` on `Mon Mar 31 19:08:22 GMT 2025`
Record UNII	8IG4632C1Y
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NSC-9351

Preferred Name

English

2-FURAMIDE

Systematic Name

English

2-FURYLAMIDE

Systematic Name

English

FURFURYLAMIDE

Systematic Name

English

FURAMIDE

Systematic Name

English

2-FURANCARBOXAMIDE

Systematic Name

English

Code System Code Type Description

NSC

9351