GSK-588045

Details

Stereochemistry	ACHIRAL
Molecular Formula	C27H28N6O2
Molecular Weight	468.5502
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=NC2=C(C=C1)C(=CC=C2)N3CCN(CCC4=CC=CC5=C4OCC6=C(N=CN56)C(N)=O)CC3

InChI

InChIKey=HLQJZFFWUXHYMB-UHFFFAOYSA-N

InChI=1S/C27H28N6O2/c1-18-8-9-20-21(30-18)5-3-6-22(20)32-14-12-31(13-15-32)11-10-19-4-2-7-23-26(19)35-16-24-25(27(28)34)29-17-33(23)24/h2-9,17H,10-16H2,1H3,(H2,28,34)

HIDE SMILES / InChI

Molecular Formula	C27H28N6O2
Molecular Weight	468.5502
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Tue Apr 01 18:07:19 GMT 2025` Edited by `admin` on `Tue Apr 01 18:07:19 GMT 2025`
Record UNII	8HG5QW7P7Z
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

4H-IMIDAZO(5,1-C)(1,4)BENZOXAZINE-3-CARBOXAMIDE, 6-(2-(4-(2-METHYL-5-QUINOLINYL)-1-PIPERAZINYL)ETHYL)-

Preferred Name

English

GSK-588045

Code

English

6-(2-(4-(2-METHYL-5-QUINOLINYL)-1-PIPERAZINYL)ETHYL)-4H-IMIDAZO(5,1-C)(1,4)BENZOXAZINE-3-CARBOXAMIDE

Systematic Name

English

6-(2-(4-(2-METHYLQUINOLIN-5-YL)PIPERAZIN-1-YL)ETHYL)-4H-BENZO(B)IMIDAZO(1,5-D)(1,4)OXAZINE-3-CARBOXAMIDE

Systematic Name

English

6-(2-(4-(2-METHYL-5-QUINOLYL)PIPERAZIN-1-YL)ETHYL)-4H-IMIDAZO(5,1-C)(1,4)BENZOXAZINE-3-CARBOXAMIDE

Systematic Name

English

Code System Code Type Description

SMS_ID

300000046514

Created by admin on Tue Apr 01 18:07:19 GMT 2025 , Edited by admin on Tue Apr 01 18:07:19 GMT 2025

PRIMARY

PUBCHEM

11655728

Created by admin on Tue Apr 01 18:07:19 GMT 2025 , Edited by admin on Tue Apr 01 18:07:19 GMT 2025

PRIMARY

CAS

876922-98-4

Created by admin on Tue Apr 01 18:07:19 GMT 2025 , Edited by admin on Tue Apr 01 18:07:19 GMT 2025

PRIMARY

FDA UNII

8HG5QW7P7Z

Created by admin on Tue Apr 01 18:07:19 GMT 2025 , Edited by admin on Tue Apr 01 18:07:19 GMT 2025

PRIMARY

Related Record Type Details


					8HG5QW7P7Z

GSK-588045

ACTIVE MOIETY

Amount:


					8HG5QW7P7Z

GSK-588045

ACTIVE MOIETY

Comments:

Originator: GlaxoSmithKline; Class: Antidepressant, Anxiolytic, Benzoxazine; Mechanism of Action: Serotonin 1 receptor antagonist; Highest Development Phases: No development reported for Anxiety disorders, Depressive disorders; Most Recent Events: 21 Apr 2011 No development reported - Phase-I for Depressive disorders in USA (unspecified route), 21 Apr 2011 No development reported - Phase-I for Anxiety disorders in USA (unspecified route)

Amount: