| Stereochemistry | ABSOLUTE |
| Molecular Formula | C37H50N2O10 |
| Molecular Weight | 682.8003 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 14 / 14 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CCN1C[C@]4(COC(=O)C2=CC=CC=C2N3C(=O)C[C@H](C)C3=O)CC[C@H](OC)[C@]56[C@@H]7C[C@H]8[C@H](OC)[C@@H]7[C@](O)(C[C@@H]8OC)[C@@](O)([C@@H](OC)[C@H]45)[C@@H]16
InChI
InChIKey=XLTANAWLDBYGFU-HTWFBASDSA-N
InChI=1S/C37H50N2O10/c1-7-38-17-34(18-49-32(42)20-10-8-9-11-23(20)39-26(40)14-19(2)31(39)41)13-12-25(46-4)36-22-15-21-24(45-3)16-35(43,27(22)28(21)47-5)37(44,33(36)38)30(48-6)29(34)36/h8-11,19,21-22,24-25,27-30,33,43-44H,7,12-18H2,1-6H3/t19-,21+,22+,24-,25-,27+,28-,29+,30-,33-,34-,35+,36+,37+/m0/s1
| Molecular Formula | C37H50N2O10 |
| Molecular Weight | 682.8003 |
| Charge | 0 |
| Count |
MOL RATIO
1 MOL RATIO (average) |
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 14 / 14 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Methyllycaconitine is a diterpenoid alkaloid found in many species of Delphinium (larkspurs). Methyllycaconitine is a potent antagonist for α7-containing neuronal nicotinic receptors. Methyllycaconitine (as mellictin) is used in some countries as a myorelaxant for treatment of pyramidal and extrapyramidal motoric disorders, such as pyramidal insufficiency, Parkinson disease, meningocephalitis and other disorders.
CNS Activity
Approval Year
PubMed
Sample Use Guides
Methyllycaconitine is administered daily, as oral tablets, 0.02 g/day once daily. The dose is increased up to 5 times a day.
Route of Administration:
Oral