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Details

Stereochemistry ABSOLUTE
Molecular Formula C21H24F3N3O4.ClH
Molecular Weight 475.889
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LASCUFLOXACIN HYDROCHLORIDE

SMILES

Cl.COC1=C2N(CCF)C=C(C(O)=O)C(=O)C2=CC(F)=C1N3C[C@@H](F)[C@@H](CNC4CC4)C3

InChI

InChIKey=YQHZQIJEMFMUGH-DFIJPDEKSA-N
InChI=1S/C21H24F3N3O4.ClH/c1-31-20-17-13(19(28)14(21(29)30)9-26(17)5-4-22)6-15(23)18(20)27-8-11(16(24)10-27)7-25-12-2-3-12;/h6,9,11-12,16,25H,2-5,7-8,10H2,1H3,(H,29,30);1H/t11-,16+;/m0./s1

HIDE SMILES / InChI
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C21H24F3N3O4
Molecular Weight 439.4282
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

LASCUFLOXACIN, a fluoroquinolone derivative, is an antibacterial agent with a broad spectrum of activity against various clinical isolates. It is under development for the treatment of respiratory tract infections and community-acquired pneumonia.

Originator

Approval Year

Unknown
139594
PubMed

PubMed

TitleDatePubMed
In Vitro Activities and Spectrum of the Novel Fluoroquinolone Lascufloxacin (KRP-AM1977).
2017 Jun
Intrapulmonary Pharmacokinetics of Lascufloxacin in Healthy Adult Volunteers.
2018 Apr
In vitro activity of lascufloxacin, a novel fluoroquinolone antibacterial agent, against various clinical isolates of anaerobes and Streptococcus anginosus group.
2018 Dec
Substance Class Chemical
Created
by admin
on Sat Dec 16 07:02:06 GMT 2023
Edited
by admin
on Sat Dec 16 07:02:06 GMT 2023
Record UNII
8GYE97TPKI
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LASCUFLOXACIN HYDROCHLORIDE
WHO-DD  
Common Name English
LASCUFLOXACIN HYDROCHLORIDE [JAN]
Common Name English
3-QUINOLINECARBOXYLIC ACID, 7-((3S,4S)-3-((CYCLOPROPYLAMINO)METHYL)-4-FLUORO-1-PYRROLIDINYL)-6-FLUORO-1-(2-FLUOROETHYL)-1,4-DIHYDRO-8-METHOXY-4-OXO-, HYDROCHLORIDE (1:1)
Systematic Name English
Lascufloxacin hydrochloride [WHO-DD]
Common Name English
Code System Code Type Description
SMS_ID
300000032940
Created by admin on Sat Dec 16 07:02:06 GMT 2023 , Edited by admin on Sat Dec 16 07:02:06 GMT 2023
PRIMARY
FDA UNII
8GYE97TPKI
Created by admin on Sat Dec 16 07:02:06 GMT 2023 , Edited by admin on Sat Dec 16 07:02:06 GMT 2023
PRIMARY
PUBCHEM
71528767
Created by admin on Sat Dec 16 07:02:06 GMT 2023 , Edited by admin on Sat Dec 16 07:02:06 GMT 2023
PRIMARY
CAS
1433857-09-0
Created by admin on Sat Dec 16 07:02:06 GMT 2023 , Edited by admin on Sat Dec 16 07:02:06 GMT 2023
PRIMARY
Related Record Type Details
Structure of LASCUFLOXACIN
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of LASCUFLOXACIN
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