8-EPI-XANTHATIN

C[C@H]1C[C@H]2OC(=O)C(=C)[C@H]2CC=C1\C=C\C(C)=O

InChIKey=RBRPTFMVULVGIC-MDKNCZOUSA-N

InChI=1S/C15H18O3/c1-9-8-14-13(11(3)15(17)18-14)7-6-12(9)5-4-10(2)16/h4-6,9,13-14H,3,7-8H2,1-2H3/b5-4+/t9-,13+,14+/m0/s1

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	1
Optical Activity	UNSPECIFIED

PubMed

Title	Date	PubMed
(-)-Xanthatin up-regulation of the GADD45γ tumor suppressor gene in MDA-MB-231 breast cancer cells: role of topoisomerase IIα inhibition and reactive oxygen species.	2013-03-08	23313378
(-)-Xanthatin induces the prolonged expression of c-Fos through an N-acetyl-L-cysteine (NAC)-sensitive mechanism in human breast cancer MDA-MB-231 cells.	2013	23824011
(--)-Xanthatin selectively induces GADD45γ and stimulates caspase-independent cell death in human breast cancer MDA-MB-231 cells.	2011-06-20	21568272

Substance Class	Chemical Created by `admin` on `Wed Apr 02 10:21:29 GMT 2025` Edited by `admin` on `Wed Apr 02 10:21:29 GMT 2025`
Record UNII	8DFW6D5G55
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

(+)-8-EPI-XANTHATIN

Preferred Name

English

8-EPI-XANTHATIN

Common Name

English

2H-CYCLOHEPTA(B)FURAN-2-ONE, 3,3A,4,7,8,8A-HEXAHYDRO-7-METHYL-3-METHYLENE-6-((1E)-3-OXO-1-BUTEN-1-YL)-, (3AR,7S,8AR)-

Systematic Name

English

2H-CYCLOHEPTA(B)FURAN-2-ONE, 3,3A,4,7,8,8A-HEXAHYDRO-7-METHYL-3-METHYLENE-6-(3-OXO-1-BUTENYL)-, (3AR,6(E),7S,8AR)-

Systematic Name

English

2H-CYCLOHEPTA(B)FURAN-2-ONE, 3,3A,4,7,8,8A-HEXAHYDRO-7-METHYL-3-METHYLENE-6-(3-OXO-1-BUTENYL)-, (3AR-(3A.ALPHA.,6(E),7.BETA.,8A.ALPHA.))-

Systematic Name

English

Code System Code Type Description

FDA UNII

8DFW6D5G55

Created by admin on Wed Apr 02 10:21:29 GMT 2025 , Edited by admin on Wed Apr 02 10:21:29 GMT 2025

PRIMARY

CAS

30890-35-8

Created by admin on Wed Apr 02 10:21:29 GMT 2025 , Edited by admin on Wed Apr 02 10:21:29 GMT 2025

PRIMARY

PUBCHEM

11694445

Created by admin on Wed Apr 02 10:21:29 GMT 2025 , Edited by admin on Wed Apr 02 10:21:29 GMT 2025

PRIMARY