U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Description

Arsphenamine (brand name Salvarsan), a drug contains arsenic, was used to treat syphilis, but then it was substituted by the more active and less toxic agent.

Originator

Alfred Bertheim
2
Curator's Comment: Alfred Bertheim, and tested on spirochaetes by Ehrlich's assistants

Approval Year

1910
2
PubMed

PubMed

TitleDatePubMed
[Evolution of treatment of syphilis through history].
2018-12
History of antibiotics. From salvarsan to cephalosporins.
2012-04
The introduction of 'chemotherapy' using arsphenamine - the first magic bullet.
2009-08
Substance Class Mixture
Created
by admin
on Mon Mar 31 19:18:35 GMT 2025
Edited
by admin
on Mon Mar 31 19:18:35 GMT 2025
Record UNII
8BAJ8WP85I
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ARSPHENAMINE
MART.   MI   WHO-DD  
Common Name English
606
Preferred Name English
Arsphenamine [WHO-DD]
Common Name English
ARSPHENAMINE [MART.]
Common Name English
SALVARSAN
Common Name English
NSC-3097
Code English
ARSPHENAMINE [MI]
Common Name English
Code System Code Type Description
MESH
D001153
Created by admin on Mon Mar 31 19:18:35 GMT 2025 , Edited by admin on Mon Mar 31 19:18:35 GMT 2025
PRIMARY
EVMPD
SUB12943MIG
Created by admin on Mon Mar 31 19:18:35 GMT 2025 , Edited by admin on Mon Mar 31 19:18:35 GMT 2025
PRIMARY
ECHA (EC/EINECS)
205-386-6
Created by admin on Mon Mar 31 19:18:35 GMT 2025 , Edited by admin on Mon Mar 31 19:18:35 GMT 2025
PRIMARY
SMS_ID
100000077435
Created by admin on Mon Mar 31 19:18:35 GMT 2025 , Edited by admin on Mon Mar 31 19:18:35 GMT 2025
PRIMARY
CAS
139-93-5
Created by admin on Mon Mar 31 19:18:35 GMT 2025 , Edited by admin on Mon Mar 31 19:18:35 GMT 2025
PRIMARY
EPA CompTox
DTXSID00930272
Created by admin on Mon Mar 31 19:18:35 GMT 2025 , Edited by admin on Mon Mar 31 19:18:35 GMT 2025
PRIMARY
CHEBI
9016
Created by admin on Mon Mar 31 19:18:35 GMT 2025 , Edited by admin on Mon Mar 31 19:18:35 GMT 2025
PRIMARY
NSC
3097
Created by admin on Mon Mar 31 19:18:35 GMT 2025 , Edited by admin on Mon Mar 31 19:18:35 GMT 2025
PRIMARY
FDA UNII
8BAJ8WP85I
Created by admin on Mon Mar 31 19:18:35 GMT 2025 , Edited by admin on Mon Mar 31 19:18:35 GMT 2025
PRIMARY
MERCK INDEX
m2071
Created by admin on Mon Mar 31 19:18:35 GMT 2025 , Edited by admin on Mon Mar 31 19:18:35 GMT 2025
PRIMARY Merck Index
All of the following components must be present:
Structure of ARSPHENAMINE, TRIMER
Structure of ARSPHENAMINE, PENTAMER
Definition References
NIH
NCATS
PRIVACY NOTICE
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966