U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
Arsphenamine (brand name Salvarsan), a drug contains arsenic, was used to treat syphilis, but then it was substituted by the more active and less toxic agent.

Originator

Curator's Comment: Alfred Bertheim, and tested on spirochaetes by Ehrlich's assistants

Approval Year

PubMed

PubMed

TitleDatePubMed
The introduction of 'chemotherapy' using arsphenamine - the first magic bullet.
2009 Aug
History of antibiotics. From salvarsan to cephalosporins.
2012 Apr
[Evolution of treatment of syphilis through history].
2018 Dec
Substance Class Mixture
Created
by admin
on Fri Dec 15 18:39:29 GMT 2023
Edited
by admin
on Fri Dec 15 18:39:29 GMT 2023
Record UNII
8BAJ8WP85I
Record Status Validated (UNII)
Record Version
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Name Type Language
ARSPHENAMINE
MART.   MI   WHO-DD  
Common Name English
Arsphenamine [WHO-DD]
Common Name English
ARSPHENAMINE [MART.]
Common Name English
SALVARSAN
Common Name English
NSC-3097
Code English
606
Code English
ARSPHENAMINE [MI]
Common Name English
Code System Code Type Description
MESH
D001153
Created by admin on Fri Dec 15 18:39:29 GMT 2023 , Edited by admin on Fri Dec 15 18:39:29 GMT 2023
PRIMARY
EVMPD
SUB12943MIG
Created by admin on Fri Dec 15 18:39:29 GMT 2023 , Edited by admin on Fri Dec 15 18:39:29 GMT 2023
PRIMARY
ECHA (EC/EINECS)
205-386-6
Created by admin on Fri Dec 15 18:39:29 GMT 2023 , Edited by admin on Fri Dec 15 18:39:29 GMT 2023
PRIMARY
CAS
139-93-5
Created by admin on Fri Dec 15 18:39:29 GMT 2023 , Edited by admin on Fri Dec 15 18:39:29 GMT 2023
PRIMARY
EPA CompTox
DTXSID00930272
Created by admin on Fri Dec 15 18:39:29 GMT 2023 , Edited by admin on Fri Dec 15 18:39:29 GMT 2023
PRIMARY
CHEBI
9016
Created by admin on Fri Dec 15 18:39:29 GMT 2023 , Edited by admin on Fri Dec 15 18:39:29 GMT 2023
PRIMARY
NSC
3097
Created by admin on Fri Dec 15 18:39:29 GMT 2023 , Edited by admin on Fri Dec 15 18:39:29 GMT 2023
PRIMARY
FDA UNII
8BAJ8WP85I
Created by admin on Fri Dec 15 18:39:29 GMT 2023 , Edited by admin on Fri Dec 15 18:39:29 GMT 2023
PRIMARY
MERCK INDEX
m2071
Created by admin on Fri Dec 15 18:39:29 GMT 2023 , Edited by admin on Fri Dec 15 18:39:29 GMT 2023
PRIMARY Merck Index
All of the following components must be present:
Definition References