U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:22:53 GMT 2023
Edited
by admin
on Sat Dec 16 14:22:53 GMT 2023
Protein Type FUSION PROTEINS
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
8B8VV1W6FZ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
IZOKIBEP
INN   USAN  
Official Name English
Izokibep [WHO-DD]
Common Name English
ABY-035/AFO2
Common Name English
FUSION PROTEIN COMPOSED OF 3 BINDING DOMAINS CONSISTING OF THREE-ALPHA-HELIX MOTIFS, EACH DERIVED FROM THE IMMUNOGLOBULIN (IG)-BINDING Z-DOMAIN OF STAPHYLOCOCCAL PROTEIN A (SPA), ENGINEERED FOR BINDING TO TWO HOMODIMER SUBUNITS OF HUMAN INTERLEUKIN 17A (
Common Name English
IZOKIBEP [USAN]
Common Name English
AFFIBODY ABY-035 (RECOMBINANT HUMAN INTERLEUKIN 17A-BINDING)
Common Name English
IMG-020
Code English
izokibep [INN]
Common Name English
ABY-035
Code English
ABY035
Code English
Code System Code Type Description
FDA UNII
8B8VV1W6FZ
Created by admin on Sat Dec 16 14:22:53 GMT 2023 , Edited by admin on Sat Dec 16 14:22:53 GMT 2023
PRIMARY
USAN
JK-250
Created by admin on Sat Dec 16 14:22:53 GMT 2023 , Edited by admin on Sat Dec 16 14:22:53 GMT 2023
PRIMARY
CAS
2226130-02-3
Created by admin on Sat Dec 16 14:22:53 GMT 2023 , Edited by admin on Sat Dec 16 14:22:53 GMT 2023
PRIMARY
NCI_THESAURUS
C175101
Created by admin on Sat Dec 16 14:22:53 GMT 2023 , Edited by admin on Sat Dec 16 14:22:53 GMT 2023
PRIMARY
INN
11121
Created by admin on Sat Dec 16 14:22:53 GMT 2023 , Edited by admin on Sat Dec 16 14:22:53 GMT 2023
PRIMARY
Related Record Type Details
TARGET -> INHIBITOR
BINDER->LIGAND
Fusion of an albumin binding domain in between the two IL-17A binding Affibody domains increases the molecule’s plasma half-life.
BINDING
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL