Firastotug

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 15:03:45 UTC 2023` Edited by `admin` on `Sat Dec 16 15:03:45 UTC 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	8B1J60R28A
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Firastotug

Official Name

English

Immunoglobulin G1-kappa, anti-[Homo sapiens CTLA4 (cytotoxic T-lymphocyte associated protein 4, CTLA-4, CD152)], humanized monoclonal antibody

Common Name

English

firastotug [INN]

Common Name

English

Gamma1 heavy chain humanized (1-446) [VH (Homo sapiens IGHV3-7*01 (77.8%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [9.7.9] (26-34.52-58.97-105)) (1-116) -Homo sapiens IGHG1*01 (100%), G1m17,1 CH1 K120, D12, L14 (CH1 K120 (213) (17-214), hinge 1-15 (215-229), C

Common Name

English

ADG116

Code

English

ADG 116 [WHO-DD]

Common Name

English

Immunoglobulin G1, anti-(human cytotoxic T-lymphocyte-associated protein 4) (human monoclonal ADG116 γ1-chain), disulfide with human monoclonal ADG116 κ-chain, dimer

Common Name

English

ADG-116

Code

English

Code System Code Type Description

CAS

2750031-14-0

Created by admin on Sat Dec 16 15:03:45 UTC 2023 , Edited by admin on Sat Dec 16 15:03:45 UTC 2023

PRIMARY

FDA UNII

8B1J60R28A

Created by admin on Sat Dec 16 15:03:45 UTC 2023 , Edited by admin on Sat Dec 16 15:03:45 UTC 2023

PRIMARY

INN

12569

Created by admin on Sat Dec 16 15:03:45 UTC 2023 , Edited by admin on Sat Dec 16 15:03:45 UTC 2023

PRIMARY

NCI_THESAURUS

C166139

Created by admin on Sat Dec 16 15:03:45 UTC 2023 , Edited by admin on Sat Dec 16 15:03:45 UTC 2023

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_143	2_199
2_219	4_215
2_260	2_320
1_143	1_199
2_366	2_424
3_23	3_89
3_135	3_195
4_23	4_89
4_135	4_195
1_219	3_215
1_225	2_225
1_228	2_228
1_260	1_320
1_366	1_424

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_296
N	2_296

Related Record Type Details


					8B1J60R28A

Firastotug

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL