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Details

Stereochemistry ACHIRAL
Molecular Formula 2C3H5O2.Ca
Molecular Weight 186.219
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CALCIUM PROPIONATE

SMILES

[Ca++].CCC([O-])=O.CCC([O-])=O

InChI

InChIKey=BCZXFFBUYPCTSJ-UHFFFAOYSA-L
InChI=1S/2C3H6O2.Ca/c2*1-2-3(4)5;/h2*2H2,1H3,(H,4,5);/q;;+2/p-2

HIDE SMILES / InChI

Molecular Formula Ca
Molecular Weight 40.078
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C3H5O2
Molecular Weight 73.0706
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Calcium propionate (E282) is a preservative, antimould and antirope agent. Calcium propionate has been widely used as a preservative in bakery and in bread. The addition of 0.3 % calcium propionate prolonged the shelf-life of salt reduced bread to 10-12 days. It is sometimes not carefully used, or a high concentration is added to preserve products. High consumption of calcium propionate can lead to several health problems. Calcium propionate is used to prevent milk fever in cows and as a feed supplement. It is considered to be safe and effective treatment given for one or two days to prevent milk fever and/or to support treatment of milk fever. Calcium propionate is generally recognized as safe by FDA when used in accordance with good manufacturing or feeding practice.

Approval Year

Sourcing

Sourcing

Vendor/AggregatorIDURL
PubMed

PubMed

TitleDatePubMed
Effect of calcium propionate and water activity on growth and aflatoxins production by Aspergillus flavus.
2010 Mar
The effect of sourdough and calcium propionate on the microbial shelf-life of salt reduced bread.
2012 Oct
Fast and simple method for semiquantitative determination of calcium propionate in bread samples.
2017 Apr
Patents

Sample Use Guides

Dosing with 349 g calcium propionate in molasses increased plasma total calcium (Catot) concentration by 10% in lactating and non-lactating cows for periods less than 7 h, and this was not augmented by simultaneous administration of MgO or treatment 24 h earlier with 349 g calcium propionate in molasses.
Route of Administration: Oral
The efficacy of calcium propionate at 2 different doses (0.5% and 1%) against growth and aflatoxins production by Aspergillus flavus (A-2092) was investigated in vitro on Czapek yeast extract agar at different levels of water activity (a(w)) in the range of 0.94 to 0.996a(w). A. flavus spores germinated on all calcium propionate and a(w) treatments; however, 1% calcium propionate at 0.94 a(w) delayed the germination process for up to 10 d. The growing rate of mycelia was slower (0.28 mm/d) at 1% calcium propionate and 0.94 a(w). Aflatoxins (B1, B2, G1, and G2) were also produced minimally (36.1, 1, 1.86, and 1.01 ng/g of media, respectively) at the aforementioned dose rate of calcium propionate and water activity. It was concluded that addition of calcium propionate and a(w) amelioration can prove effective tools for suppressing the germination, growth rate, and aflatoxins production by A. flavus in substrate.
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:08:16 GMT 2023
Edited
by admin
on Fri Dec 15 15:08:16 GMT 2023
Record UNII
8AI80040KW
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CALCIUM PROPIONATE
FCC   HSDB   INCI   MART.   MI   WHO-DD  
INCI  
Official Name English
CALCIUM PROPANOATE
Systematic Name English
PROPANOIC ACID, CALCIUM SALT (2:1)
Common Name English
Ca-PROPIONATE
Common Name English
CALCIUM PROPIONATE (E 282)
Common Name English
CALCIUM PROPIONATE [MART.]
Common Name English
Calcium propionate [WHO-DD]
Common Name English
PROPIONIC ACID, CALCIUM SALT
Common Name English
CALCIUM PROPIONATE [HSDB]
Common Name English
PROPANOIC ACID, CALCIUM SALT
Common Name English
E-282
Code English
INS-282
Code English
CALCIUM PROPIONATE [MI]
Common Name English
CALCIUM PROPIONATE [INCI]
Common Name English
CALCIUM PROPIONATE [FCC]
Common Name English
INS NO.282
Code English
Classification Tree Code System Code
EPA PESTICIDE CODE 77701
Created by admin on Fri Dec 15 15:08:17 GMT 2023 , Edited by admin on Fri Dec 15 15:08:17 GMT 2023
CODEX ALIMENTARIUS (GSFA) INS-282
Created by admin on Fri Dec 15 15:08:17 GMT 2023 , Edited by admin on Fri Dec 15 15:08:17 GMT 2023
JECFA EVALUATION INS-282
Created by admin on Fri Dec 15 15:08:17 GMT 2023 , Edited by admin on Fri Dec 15 15:08:17 GMT 2023
CFR 21 CFR 184.1221
Created by admin on Fri Dec 15 15:08:17 GMT 2023 , Edited by admin on Fri Dec 15 15:08:17 GMT 2023
Code System Code Type Description
RXCUI
1426453
Created by admin on Fri Dec 15 15:08:17 GMT 2023 , Edited by admin on Fri Dec 15 15:08:17 GMT 2023
PRIMARY RxNorm
ECHA (EC/EINECS)
223-795-8
Created by admin on Fri Dec 15 15:08:17 GMT 2023 , Edited by admin on Fri Dec 15 15:08:17 GMT 2023
PRIMARY
DAILYMED
8AI80040KW
Created by admin on Fri Dec 15 15:08:17 GMT 2023 , Edited by admin on Fri Dec 15 15:08:17 GMT 2023
PRIMARY
EPA CompTox
DTXSID1027556
Created by admin on Fri Dec 15 15:08:17 GMT 2023 , Edited by admin on Fri Dec 15 15:08:17 GMT 2023
PRIMARY
GRAS Notification (GRN No.)
786
Created by admin on Fri Dec 15 15:08:17 GMT 2023 , Edited by admin on Fri Dec 15 15:08:17 GMT 2023
PRIMARY
WIKIPEDIA
CALCIUM PROPANOATE
Created by admin on Fri Dec 15 15:08:17 GMT 2023 , Edited by admin on Fri Dec 15 15:08:17 GMT 2023
PRIMARY
SMS_ID
100000076594
Created by admin on Fri Dec 15 15:08:17 GMT 2023 , Edited by admin on Fri Dec 15 15:08:17 GMT 2023
PRIMARY
EVMPD
SUB13196MIG
Created by admin on Fri Dec 15 15:08:17 GMT 2023 , Edited by admin on Fri Dec 15 15:08:17 GMT 2023
PRIMARY
GRAS Notification (GRN No.)
157
Created by admin on Fri Dec 15 15:08:17 GMT 2023 , Edited by admin on Fri Dec 15 15:08:17 GMT 2023
PRIMARY
HSDB
907
Created by admin on Fri Dec 15 15:08:17 GMT 2023 , Edited by admin on Fri Dec 15 15:08:17 GMT 2023
PRIMARY
PUBCHEM
19999
Created by admin on Fri Dec 15 15:08:17 GMT 2023 , Edited by admin on Fri Dec 15 15:08:17 GMT 2023
PRIMARY
FDA UNII
8AI80040KW
Created by admin on Fri Dec 15 15:08:17 GMT 2023 , Edited by admin on Fri Dec 15 15:08:17 GMT 2023
PRIMARY
CAS
4075-81-4
Created by admin on Fri Dec 15 15:08:17 GMT 2023 , Edited by admin on Fri Dec 15 15:08:17 GMT 2023
PRIMARY
RS_ITEM_NUM
1087053
Created by admin on Fri Dec 15 15:08:17 GMT 2023 , Edited by admin on Fri Dec 15 15:08:17 GMT 2023
PRIMARY
MERCK INDEX
m2970
Created by admin on Fri Dec 15 15:08:17 GMT 2023 , Edited by admin on Fri Dec 15 15:08:17 GMT 2023
PRIMARY Merck Index
Related Record Type Details
PARENT -> SALT/SOLVATE