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Details

Stereochemistry ABSOLUTE
Molecular Formula C14H24N6O4.C2H4O2
Molecular Weight 400.4301
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PREZATIDE MONOACETATE

SMILES

CC(O)=O.NCCCC[C@H](NC(=O)[C@H](CC1=CNC=N1)NC(=O)CN)C(O)=O

InChI

InChIKey=MGNUTAFMLGJBGV-ACMTZBLWSA-N
InChI=1S/C14H24N6O4.C2H4O2/c15-4-2-1-3-10(14(23)24)20-13(22)11(19-12(21)6-16)5-9-7-17-8-18-9;1-2(3)4/h7-8,10-11H,1-6,15-16H2,(H,17,18)(H,19,21)(H,20,22)(H,23,24);1H3,(H,3,4)/t10-,11-;/m0./s1

HIDE SMILES / InChI

Molecular Formula C2H4O2
Molecular Weight 60.052
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C14H24N6O4
Molecular Weight 340.3782
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Prezatide is a tripeptide molecule consisiting of lysine, glycine and histidine, also known as GHK (glycyl-L-histidyl-L-lysine), that forms a complex with copper ions. Prezatide is used in cosmetic products (skin and hair) and is known help wound healing. Prezatide increases the synthesis and deposition of type I collagen and glycosaminoglycan. It is thought to play a role in the modulation of tissue remodeling by increases the expression of matrix metalloproteinase-2, as well as tissue inhibitor of matrix metalloproteinases-1 and -2. Prezatide has antioxidant activity due to its ability to supply copper for superoxide dismutase and anti-inflammatory ability due to the blockage the of iron (Fe2+) release during injury.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Inactive ingredient
Volu-Firm

Approved Use

Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:51:57 UTC 2023
Edited
by admin
on Fri Dec 15 15:51:57 UTC 2023
Record UNII
8AA809EUS9
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PREZATIDE MONOACETATE
Common Name English
GHK ACETATE
MI  
Common Name English
PC-1020 MONOACETATE
Code English
L-LYSINE, N2-(N-GLYCYL-L-HISTIDYL)-, MONOACETATE
Common Name English
GHK ACETATE [MI]
Common Name English
L-LYSINE, GLYCYL-L-HISTIDYL-, MONOACETATE
Common Name English
Code System Code Type Description
FDA UNII
8AA809EUS9
Created by admin on Fri Dec 15 15:51:57 UTC 2023 , Edited by admin on Fri Dec 15 15:51:57 UTC 2023
PRIMARY
CAS
72957-37-0
Created by admin on Fri Dec 15 15:51:57 UTC 2023 , Edited by admin on Fri Dec 15 15:51:57 UTC 2023
PRIMARY
PUBCHEM
22214678
Created by admin on Fri Dec 15 15:51:57 UTC 2023 , Edited by admin on Fri Dec 15 15:51:57 UTC 2023
PRIMARY
MERCK INDEX
m5722
Created by admin on Fri Dec 15 15:51:57 UTC 2023 , Edited by admin on Fri Dec 15 15:51:57 UTC 2023
PRIMARY Merck Index
ECHA (EC/EINECS)
277-125-4
Created by admin on Fri Dec 15 15:51:57 UTC 2023 , Edited by admin on Fri Dec 15 15:51:57 UTC 2023
PRIMARY
DRUG BANK
DBSALT002421
Created by admin on Fri Dec 15 15:51:57 UTC 2023 , Edited by admin on Fri Dec 15 15:51:57 UTC 2023
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE