U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C7H13NO
Molecular Weight 127.1842
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CYCLOHEXANECARBOXAMIDE

SMILES

NC(=O)C1CCCCC1

InChI

InChIKey=PNZXMIKHJXIPEK-UHFFFAOYSA-N
InChI=1S/C7H13NO/c8-7(9)6-4-2-1-3-5-6/h6H,1-5H2,(H2,8,9)

HIDE SMILES / InChI

Molecular Formula C7H13NO
Molecular Weight 127.1842
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Intrinsic resistance to apoptosis of colon epithelial cells is a potential determining factor in the susceptibility of the A/J mouse strain to dimethylhydrazine-induced colon tumorigenesis.
2007-12
Ceramide-induced G2 arrest in rhabdomyosarcoma (RMS) cells requires p21Cip1/Waf1 induction and is prevented by MDM2 overexpression.
2007-10
Maspin augments proteasome inhibitor-induced apoptosis in prostate cancer cells.
2007-08
Hypotonicity stimulates renal epithelial sodium transport by activating JNK via receptor tyrosine kinases.
2007-07
Biological characteristics of Chinese hamster ovary cells transfected with bovine Prnp.
2007-06
Translational control of recombinant human acetylcholinesterase accumulation in plants.
2007-05-30
The role of cargo proteins in GGA recruitment.
2007-05
A study on tinea gladiatorum in young wrestlers and dermatophyte contamination of wrestling mats from Sari, Iran.
2007-05
Role of ubiquitination in IGF-1 receptor signaling and degradation.
2007-04-04
Identification of genes implicated in methapyrilene-induced hepatotoxicity by comparing differential gene expression in target and nontarget tissue.
2007-04
In vitro actions of insulin-like growth factor-I on ovarian follicle maturation in white perch (Morone americana).
2007-04
Spotted cotton oligonucleotide microarrays for gene expression analysis.
2007-03-27
An early event in the herpes simplex virus type-2 replication cycle is sufficient to induce Chlamydia trachomatis persistence.
2007-03
Ligusticum chuanxiong prevents rat pheochromocytoma cells from serum deprivation-induced apoptosis through a protein kinase A-dependent pathway.
2007-02-12
Cell type-specific, topoisomerase II-dependent inhibition of hypoxia-inducible factor-1alpha protein accumulation by NSC 644221.
2007-02-01
Analysis of mitotic phosphorylation of borealin.
2007-01-22
Modulation of connexin expression and gap junction communication in astrocytes by the gram-positive bacterium S. aureus.
2007-01-01
Brain-derived neurotrophic factor regulates the expression of D1 dopamine receptors.
2007-01
Detection of transcriptional difference of porcine imprinted genes using different microarray platforms.
2006-12-28
Lipopolysaccharide and cyclic AMP regulation of CB(2) cannabinoid receptor levels in rat brain and mouse RAW 264.7 macrophages.
2006-12
EC5S ubiquitin complex is recruited by KSHV latent antigen LANA for degradation of the VHL and p53 tumor suppressors.
2006-10
Threshold-dependent BMP-mediated repression: a model for a conserved mechanism that patterns the neuroectoderm.
2006-10
Cytoplasmic polyadenylation controls cdc25B mRNA translation in rat oocytes resuming meiosis.
2006-07
Dexamethasone downregulates calcification-inhibitor molecules and accelerates osteogenic differentiation of vascular pericytes: implications for vascular calcification.
2006-05-26
Human retroviral host restriction factors APOBEC3G and APOBEC3F localize to mRNA processing bodies.
2006-05
[Transduction of heme oxygenase-1 gene to human Islet cells via adenovirus vector enhances anti-apoptosis function and insulin release].
2006-04-04
A multistep kinase-based sertoli cell autocrine-amplifying loop regulates prostaglandins, their receptors, and cytokines.
2006-04
Smad7 and protein phosphatase 1alpha are critical determinants in the duration of TGF-beta/ALK1 signaling in endothelial cells.
2006-03-29
EAAC1 is expressed in rat and human prostate epithelial cells; functions as a high-affinity L-aspartate transporter; and is regulated by prolactin and testosterone.
2006-03-27
The mitotic manipulation of cytotrophoblast differentiation in vitro.
2006-03-06
Human serum albumin hybrid incorporating tailed porphyrinatoiron(II) in the alpha,alpha,alpha,beta-conformer as an O2-binding site.
2006-01-19
Combining genetic and biochemical approaches to identify functional molecular contact points.
2006
Adaptively inferring human transcriptional subnetworks.
2006
Modulation of human renal cell carcinoma 786-0 MMP-2 and MMP-9 activity by inhibitors and inducers in vitro.
2006
RNA interference is not involved in natural antisense mediated regulation of gene expression in mammals.
2006
Expression of the inflammatory chemokines CCL5, CCL3 and CXCL10 in juvenile idiopathic arthritis, and demonstration of CCL5 production by an atypical subset of CD8+ T cells.
2006
Potentiation of caspase-1 activation by the P2X7 receptor is dependent on TLR signals and requires NF-kappaB-driven protein synthesis.
2005-12-01
Bmp signaling promotes intermediate mesoderm gene expression in a dose-dependent, cell-autonomous and translation-dependent manner.
2005-12-01
Tyrosine 729 of the G-CSF receptor controls the duration of receptor signaling: involvement of SOCS3 and SOCS1.
2005-10
Potential targets of transforming growth factor-beta1 during inhibition of oocyte maturation in zebrafish.
2005-09-30
Acute effects of insulin on beta-cells from transplantable human islets.
2005-09-28
A cross-talk between RNA splicing and signaling pathway alters Fas gene expression at post-transcriptional level: alternative splicing of Fas mRNA in the leukemic U937 cells.
2005-09
Life and death of lymphocytes: a role in immunesenescence.
2005-08-23
Haplotypes at the Tas2r locus on distal chromosome 6 vary with quinine taste sensitivity in inbred mice.
2005-06-06
Cultured podocytes establish a size-selective barrier regulated by specific signaling pathways and demonstrate synchronized barrier assembly in a calcium switch model of junction formation.
2005-06
Rat nicastrin gene: cDNA isolation, mRNA variants and expression pattern analysis.
2005-05-20
Nuclear proteasome activation and degradation of carboxymethylated histones in human keratinocytes following glyoxal treatment.
2005-03-15
Antrodia camphorata prevents rat pheochromocytoma cells from serum deprivation-induced apoptosis.
2005-03-01
Regulation of alternative splicing of caspase-2 through an intracellular signaling pathway in response to pro-apoptotic stimuli.
2005-02
Novel avian influenza H7N3 strain outbreak, British Columbia.
2004-12
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 17:52:26 GMT 2025
Edited
by admin
on Mon Mar 31 17:52:26 GMT 2025
Record UNII
8A54A97YCR
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NSC-16584
Preferred Name English
CYCLOHEXANECARBOXAMIDE
Systematic Name English
HEXAHYDROBENZOIC ACID AMIDE
Systematic Name English
CYCLOHEXAMETHYLENE CARBAMIDE
Common Name English
HEXAHYDROBENZAMIDE
Systematic Name English
CYCLOHEXYLCARBOXAMIDE
Common Name English
Code System Code Type Description
NSC
16584
Created by admin on Mon Mar 31 17:52:26 GMT 2025 , Edited by admin on Mon Mar 31 17:52:26 GMT 2025
PRIMARY
PUBCHEM
14283
Created by admin on Mon Mar 31 17:52:26 GMT 2025 , Edited by admin on Mon Mar 31 17:52:26 GMT 2025
PRIMARY
FDA UNII
8A54A97YCR
Created by admin on Mon Mar 31 17:52:26 GMT 2025 , Edited by admin on Mon Mar 31 17:52:26 GMT 2025
PRIMARY
ECHA (EC/EINECS)
214-351-4
Created by admin on Mon Mar 31 17:52:26 GMT 2025 , Edited by admin on Mon Mar 31 17:52:26 GMT 2025
PRIMARY
CAS
1122-56-1
Created by admin on Mon Mar 31 17:52:26 GMT 2025 , Edited by admin on Mon Mar 31 17:52:26 GMT 2025
PRIMARY
EPA CompTox
DTXSID1061528
Created by admin on Mon Mar 31 17:52:26 GMT 2025 , Edited by admin on Mon Mar 31 17:52:26 GMT 2025
PRIMARY