U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Nucleic Acid
Created
by admin
on Sat Dec 16 19:50:11 UTC 2023
Edited
by admin
on Sat Dec 16 19:50:11 UTC 2023
Nucleic Acid Type mRNA VACCINE
Nucleic Acid Subtype VIRAL ENVELOPE PROTEIN
Sequence Origin VIRAL
Sequence Type COMPLETE
Record UNII
89K3MV8294
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CX-037073
Common Name English
RNA (recombinant 5′-(m7G-(5′→5′)-ppp-Gm)-capped all uridine→N1-methylpseudouridine-substituted severe acute respiratory syndrome coronavirus 2 pre-fusion spike glycoprotein [983-proline,984-proline] CH.1.1 variant plus 5′- and 3′-untranslat
Common Name English
Code System Code Type Description
CAS
2918981-82-3
Created by admin on Sat Dec 16 19:50:11 UTC 2023 , Edited by admin on Sat Dec 16 19:50:11 UTC 2023
PRIMARY
FDA UNII
89K3MV8294
Created by admin on Sat Dec 16 19:50:11 UTC 2023 , Edited by admin on Sat Dec 16 19:50:11 UTC 2023
PRIMARY
Sugar Site Range Site Count
D-Ribose (RNA) 1_1-1_4097 4097 / 4097
Linkage Site Range Site Count
Phosphate 1_2-1_4097 4096 / 4096
Related Record Type Details
TARGET ORGANISM->VACCINE ANTIGEN
Related Record Type Details
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
NUCLEOTIDE SUBSTITUTION [1_1] 5'-GUANOSINE-M-RNA-CAP-1-3'-PHOSPHATE T0HQY09X7B
NUCLEOSIDE_SUBSTITUTION U N1-METHYLPSEUDOURIDINE 09RAD4M6WF