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Details

Stereochemistry ACHIRAL
Molecular Formula C20H25N.ClH
Molecular Weight 315.88
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PRODIPINE HYDROCHLORIDE

SMILES

Cl.CC(C)N1CCC(CC1)(C2=CC=CC=C2)C3=CC=CC=C3

InChI

InChIKey=ZFCBOUXJVGNRIF-UHFFFAOYSA-N
InChI=1S/C20H25N.ClH/c1-17(2)21-15-13-20(14-16-21,18-9-5-3-6-10-18)19-11-7-4-8-12-19;/h3-12,17H,13-16H2,1-2H3;1H

HIDE SMILES / InChI

Molecular Formula C20H25N
Molecular Weight 279.4192
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Prodipine (also known as BY-101) is diphenylpiperidines derivative patented by Chemische Fabrik Promonta G.m.b.H. as an anti parkinsonian agent. Prodipine showed monoamine oxidase inhibiting effects in vitro (liver and brain homogenates) similar to those of harmaline. In preclinical studies, Prodipine caused no tachyphylaxis, no increased salivation, or hyperthermia, and had lower toxicity in mice than amphetamine or pemoline. Prodipine decreased reserpine-induced ptosis, antagonized tremorine-induced seizures, and caused only mild hypertension in mice.

Approval Year

PubMed

PubMed

TitleDatePubMed
CSF-changes of HVA and 5-HIAA during intermittent and continuous Parkinson therapy with particular regard to prodipin application.
1978-03
Patents

Patents

Sample Use Guides

In Vivo Use Guide
20 mg
Route of Administration: Intravenous
Substance Class Chemical
Created
by admin
on Mon Mar 31 22:24:35 GMT 2025
Edited
by admin
on Mon Mar 31 22:24:35 GMT 2025
Record UNII
89CCP8Z2PS
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ANTHEN
Preferred Name English
PRODIPINE HYDROCHLORIDE
MI  
Common Name English
PRODIPINE HYDROCHLORIDE [MI]
Common Name English
BY-101
Code English
1-ISOPROPYL-4,4-DIPHENYLPIPERIDINE HYDROCHLORIDE
Systematic Name English
PIPERIDINE, 1-(1-METHYLETHYL)-4,4-DIPHENYL-, HYDROCHLORIDE (1:1)
Systematic Name English
Code System Code Type Description
CAS
31314-39-3
Created by admin on Mon Mar 31 22:24:35 GMT 2025 , Edited by admin on Mon Mar 31 22:24:35 GMT 2025
PRIMARY
MERCK INDEX
m1237
Created by admin on Mon Mar 31 22:24:35 GMT 2025 , Edited by admin on Mon Mar 31 22:24:35 GMT 2025
PRIMARY Merck Index
FDA UNII
89CCP8Z2PS
Created by admin on Mon Mar 31 22:24:35 GMT 2025 , Edited by admin on Mon Mar 31 22:24:35 GMT 2025
PRIMARY
PUBCHEM
3030531
Created by admin on Mon Mar 31 22:24:35 GMT 2025 , Edited by admin on Mon Mar 31 22:24:35 GMT 2025
PRIMARY