TETRAHYDROPIPERINE

First approved in 2013

O=C(CCCCC1=CC=C2OCOC2=C1)N3CCCCC3

InChIKey=APZYKUZPJCQGPP-UHFFFAOYSA-N

InChI=1S/C17H23NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h8-9,12H,1-7,10-11,13H2

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Conditions

Condition	Modality	Targets	Highest Phase	Product
Arthritis 87 Sources: https://www.drugs.com/otc/395776/livrelief-pain-relief.html	Inactive ingredient		Approved 8583	LivRelief Pain Relief Approved Use for the temporary relief of minor aches and pains of muscles and joints associated with simple backache, arthritis, strains, bruises, sprains

Overview

CYP3A4	CYP2C9	CYP2D6	hERG

Other Inhibitor	Other Substrate	Other Inducer
rCYP1A1/2 1 rCYP2/3 1

Drug as perpetrator

Target	Modality	Activity	Metabolite	Clinical evidence
rCYP1A1/2 3	inhibitor 4027 Sources: https://pubmed.ncbi.nlm.nih.gov/10968285/	yes [IC50 23 uM]
rCYP2/3 1	inhibitor 4027 Sources: https://pubmed.ncbi.nlm.nih.gov/10968285/	yes [IC50 25 uM]

Substance Class	Chemical Created by `admin` on `Mon Mar 31 20:38:34 GMT 2025` Edited by `admin` on `Mon Mar 31 20:38:34 GMT 2025`
Record UNII	8904DO502T
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

COSMOPERINE

Preferred Name

English

TETRAHYDROPIPERINE

Official Name

English

1-PENTANONE, 5-(1,3-BENZODIOXOL-5-YL)-1-(1-PIPERIDINYL)-

Systematic Name

English

TETRAHYDROPIPERIDINE

Common Name

English

PIPERIDINE, 1-(5-(3,4-(METHYLENEDIOXY)PHENYL)VALERYL)-

Systematic Name

English

PIPERIDINE, 1-(5-(1,3-BENZODIOXOL-5-YL)-1-OXOPENTYL)-

Systematic Name

English

Code System Code Type Description

RXCUI

1661433