U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C17H18FN3O4
Molecular Weight 347.3409
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of N-DESMETHYL LEVOFLOXACIN

SMILES

C[C@H]1COC2=C(N3CCNCC3)C(F)=CC4=C2N1C=C(C(O)=O)C4=O

InChI

InChIKey=WKRSSAPQZDHYRV-VIFPVBQESA-N
InChI=1S/C17H18FN3O4/c1-9-8-25-16-13-10(15(22)11(17(23)24)7-21(9)13)6-12(18)14(16)20-4-2-19-3-5-20/h6-7,9,19H,2-5,8H2,1H3,(H,23,24)/t9-/m0/s1

HIDE SMILES / InChI
Molecular Formula C17H18FN3O4
Molecular Weight 347.3409
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
139594
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:04:58 UTC 2023
Edited
by admin
on Fri Dec 15 16:04:58 UTC 2023
Record UNII
88ZBA45NC8
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
N-DESMETHYL LEVOFLOXACIN
Common Name English
(S)-9-FLUORO-2,3-DIHYDRO-3-METHYL-10-(PIPERAZIN-1-YL)-7-OXO-7H-PYRIDO(1,2,3-DE)(1,4)BENZOXAZINE-6-CARBOXYLIC ACID
Systematic Name English
UING 4-255
Code English
7H-PYRIDO(1,2,3-DE)-1,4-BENZOXAZINE-6-CARBOXYLIC ACID, 9-FLUORO-2,3-DIHYDRO-3-METHYL-7-OXO-10-(1-PIPERAZINYL)-, (3S)-
Common Name English
LEVOFLOXACIN HEMIHYDRATE IMPURITY B [EP IMPURITY]
Common Name English
LEVOFLOXACIN IMPURITY, N-DESMETHYL LEVOFLOXACIN- [USP IMPURITY]
Common Name English
DN-5455
Code English
N-DESMETHYL OFLOXACIN, (S)-
Common Name English
N-DESMETHYL LEVOFLOXACIN, (-)-
Common Name English
DESMETHYL LEVOFLOXACIN
Common Name English
LEVOFLOXACIN RELATED COMPOUND A [USP-RS]
Common Name English
LEVOFLOXACIN RELATED COMPOUND A [USP IMPURITY]
Common Name English
LEVOFLOXACIN RELATED COMPOUND A
USP   USP-RS  
Common Name English
(S)-9-FLUORO-3-METHYL-10-(PIPERAZIN-1-YL)-7-OXO-2,3-DIHYDRO-7H-PYRIDO(1,2,3-DE)(1,4)BENZOXAZINE-6-CARBOXYLIC ACID
Systematic Name English
Code System Code Type Description
FDA UNII
88ZBA45NC8
Created by admin on Fri Dec 15 16:04:59 UTC 2023 , Edited by admin on Fri Dec 15 16:04:59 UTC 2023
PRIMARY
PUBCHEM
10958963
Created by admin on Fri Dec 15 16:04:59 UTC 2023 , Edited by admin on Fri Dec 15 16:04:59 UTC 2023
PRIMARY
RS_ITEM_NUM
1362114
Created by admin on Fri Dec 15 16:04:59 UTC 2023 , Edited by admin on Fri Dec 15 16:04:59 UTC 2023
PRIMARY
CAS
117707-40-1
Created by admin on Fri Dec 15 16:04:59 UTC 2023 , Edited by admin on Fri Dec 15 16:04:59 UTC 2023
PRIMARY
Related Record Type Details
Structure of LEVOFLOXACIN ANHYDROUS
PARENT -> METABOLITE LESS ACTIVE
Less than 5% of an administered dose was recovered in the urine as the desmethyl and N-oxide metabolites
URINE
Related Record Type Details
Structure of LEVOFLOXACIN
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of LEVOFLOXACIN
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966