PYRROLIPHENE HYDROCHLORIDE

Details

Stereochemistry	UNKNOWN
Molecular Formula	C23H29NO2.ClH
Molecular Weight	387.943
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CC(CN1CCCC1)C(CC2=CC=CC=C2)(OC(C)=O)C3=CC=CC=C3

InChI

InChIKey=QDWFLIRNVGQZLD-UHFFFAOYSA-N

InChI=1S/C23H29NO2.ClH/c1-19(18-24-15-9-10-16-24)23(26-20(2)25,22-13-7-4-8-14-22)17-21-11-5-3-6-12-21;/h3-8,11-14,19H,9-10,15-18H2,1-2H3;1H

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C23H29NO2
Molecular Weight	351.4819
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/15714600 | https://linkinghub.elsevier.com/retrieve/pii/S0022354915339332 | https://www.ncbi.nlm.nih.gov/pubmed/4919646

Pyrroliphene is a dialkylaminodiphenylbutanol ester with antitussive and analgesic activities. In clinical trials the major side effect of Pyrroliphene was sedation, and the other side effect liabilities were similar to those of morphine.

Originator

Approval Year

PubMed

Title	Date	PubMed
Simultaneous determination of paracetamol and dextropropoxyphene in human plasma by liquid chromatography/tandem mass spectrometry: application to clinical bioequivalence studies.	2005	15714600

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:11:46 GMT 2023` Edited by `admin` on `Fri Dec 15 15:11:46 GMT 2023`
Record UNII	88Y9ABT89I
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PYRROLIPHENE HYDROCHLORIDE

Official Name

English

PYRROLIFENE HYDROCHLORIDE

Common Name

English

PYRROLIPHENE HYDROCHLORIDE [USAN]

Common Name

English

(+)-.ALPHA.-BENZYL-.BETA.-METHYL-.ALPHA.-PHENYL-1-PYRROLIDINEPROPANOL ACETATE (ESTER) HYDROCHLORIDE

Common Name

English

1-PYRROLIDINEPROPANOL, .BETA.-METHYL-.ALPHA.-PHENYL-.ALPHA.-(PHENYLMETHYL)-, ACETATE (ESTER), HYDROCHLORIDE

Common Name

English

PYRROLIPHENE HCL

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C241