U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 15:40:27 GMT 2023
Edited
by admin
on Sat Dec 16 15:40:27 GMT 2023
Protein Type STRUCTURAL PROTEIN
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
88ECG9H7RA
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CARDIAC TROPONIN I
Common Name English
TROPONIN I
Common Name English
TROPONIN I, CARDIAC MUSCLE
Common Name English
Code System Code Type Description
UNIPROT
P19429
Created by admin on Sat Dec 16 15:40:27 GMT 2023 , Edited by admin on Sat Dec 16 15:40:27 GMT 2023
PRIMARY
FDA UNII
88ECG9H7RA
Created by admin on Sat Dec 16 15:40:27 GMT 2023 , Edited by admin on Sat Dec 16 15:40:27 GMT 2023
PRIMARY
Related Record Type Details
ACTIVATOR->OFF TARGET
In 4 out of 8 patients ABBV-467 increased the levels of troponin, a protein associated with damage to the heart. This concerning side effect may impact the future development of MCL-1 inhibitors as anticancer drugs.
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL