TIDUTAMAB

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NCATS

Approval Year

Substance Class	Protein
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	88635FW2QX
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TIDUTAMAB

Official Name

English

XMAB18087

Code

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN CD3 ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONAL XMAB18087 .GAMMA.1-CHAIN), (265->231'),(268->234')-BIS(DISULFIDE) WITH IMMUNOGLOBULIN G1, ANTI-(HUMAN SOMATOSTATIN RECEPTOR 2) (HUMAN-MUS MUSCULUS MONOCLONAL XMAB18087 .GAMMA.1-CH

Systematic Name

English

XMAB-18087

Code

English

IMMUNOGLOBULIN HALF-G1-KAPPA/SCFV-H-CH2-CH3, ANTI-(HOMO SAPIENS SSTR2 (SOMATOSTATIN RECEPTOR 2) AND HOMO SAPIENS CD3 EPSILON (CD3E, LEU-4)), MONOCLONAL ANTIBODY, BISPECIFICGAMMA1 HEAVY CHAIN ANTI-SSTR2 (1-451) (VH (HOMO SAPIENS IGHV3-48*03 (90.8%)-(IGHD)

Systematic Name

English

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Classification Tree

Code System

Code

Monoclonal Antibody

NCI_THESAURUS

C28227

Antineoplastic Biological Agent

NCI_THESAURUS

C129822

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Code System

Code

Type

Description

NCI_THESAURUS

C146820

PRIMARY

CAS

2148354-90-7

PRIMARY

FDA UNII

88635FW2QX

PRIMARY

USAN

HI-138

PRIMARY

INN

11022

PRIMARY

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Subunit 0

Subunit 1

Subunit 2

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From	To
1_22	1_96
1_149	1_205
1_225	3_219
1_231	2_265
1_234	2_268

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Glycosylation Type

MAMMALIAN

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Related Record

Type

Details


					ZLW14X2D30

CD3

TARGET -> ACTIVATOR


					D73QL0OMU2

SOMATOSTATIN RECEPTOR TYPE 2

TARGET->LIGAND

Comments:

XmAb18087 Binding to Human SSTR2 Antigens Heterologously Expressed on the Surface of CHO Cells.

Interaction Type:

BINDING

Qualification:

EC50

Amount:

2.2 microgram/mL (average)

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Related Record

Type

Details


					88635FW2QX

TIDUTAMAB

ACTIVE MOIETY

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Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL	ESTIMATED 127000 Da (average)
Molecular Formula	CHEMICAL	ESTIMATED C5633H8640N1504O1740S38

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