TIDUTAMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 00:23:02 GMT 2025` Edited by `admin` on `Wed Apr 02 00:23:02 GMT 2025`
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	88635FW2QX
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

XMAB-18087

Preferred Name

English

TIDUTAMAB

Official Name

English

XMAB18087

Code

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN CD3 ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONAL XMAB18087 .GAMMA.1-CHAIN), (265->231'),(268->234')-BIS(DISULFIDE) WITH IMMUNOGLOBULIN G1, ANTI-(HUMAN SOMATOSTATIN RECEPTOR 2) (HUMAN-MUS MUSCULUS MONOCLONAL XMAB18087 .GAMMA.1-CH

Systematic Name

English

IMMUNOGLOBULIN HALF-G1-KAPPA/SCFV-H-CH2-CH3, ANTI-(HOMO SAPIENS SSTR2 (SOMATOSTATIN RECEPTOR 2) AND HOMO SAPIENS CD3 EPSILON (CD3E, LEU-4)), MONOCLONAL ANTIBODY, BISPECIFICGAMMA1 HEAVY CHAIN ANTI-SSTR2 (1-451) (VH (HOMO SAPIENS IGHV3-48*03 (90.8%)-(IGHD)

Systematic Name

English

TIDUTAMAB [USAN]

Common Name

English

Tidutamab [WHO-DD]

Common Name

English

ANTI-SSTR2/CD3 MONOCLONAL ANTIBODY XMAB18087

Common Name

English

tidutamab [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C28227

Created by admin on Wed Apr 02 00:23:02 GMT 2025 , Edited by admin on Wed Apr 02 00:23:02 GMT 2025

NCI_THESAURUS

C129822

Created by admin on Wed Apr 02 00:23:02 GMT 2025 , Edited by admin on Wed Apr 02 00:23:02 GMT 2025

Code System Code Type Description

NCI_THESAURUS

C146820

Created by admin on Wed Apr 02 00:23:02 GMT 2025 , Edited by admin on Wed Apr 02 00:23:02 GMT 2025

PRIMARY

CAS

2148354-90-7

Created by admin on Wed Apr 02 00:23:02 GMT 2025 , Edited by admin on Wed Apr 02 00:23:02 GMT 2025

PRIMARY

SMS_ID

300000005939

Created by admin on Wed Apr 02 00:23:02 GMT 2025 , Edited by admin on Wed Apr 02 00:23:02 GMT 2025

PRIMARY

FDA UNII

88635FW2QX

Created by admin on Wed Apr 02 00:23:02 GMT 2025 , Edited by admin on Wed Apr 02 00:23:02 GMT 2025

PRIMARY

USAN

HI-138

Created by admin on Wed Apr 02 00:23:02 GMT 2025 , Edited by admin on Wed Apr 02 00:23:02 GMT 2025

PRIMARY

INN

11022

Created by admin on Wed Apr 02 00:23:02 GMT 2025 , Edited by admin on Wed Apr 02 00:23:02 GMT 2025

PRIMARY

From	To
1_22	1_96
1_149	1_205
1_225	3_219
1_231	2_265
1_234	2_268
1_265	1_325
1_371	1_429
2_22	2_98
2_167	2_235
2_299	2_359
2_405	2_463
3_23	3_94
3_139	3_199

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_301
N	2_335

Related Record Type Details


					ZLW14X2D30

CD3

TARGET -> ACTIVATOR


					D73QL0OMU2

SOMATOSTATIN RECEPTOR TYPE 2

TARGET->LIGAND

Comments:

XmAb18087 Binding to Human SSTR2 Antigens Heterologously Expressed on the Surface of CHO Cells.

Interaction Type:

BINDING

Qualification:

EC50

Amount:

Related Record Type Details


					88635FW2QX

TIDUTAMAB

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_451] [2_485]	C-TERMINUS			LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL