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Details

Stereochemistry ABSOLUTE
Molecular Formula C3H7NO5S2
Molecular Weight 201.221
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of S-SULFOCYSTEINE

SMILES

N[C@@H](CSS(O)(=O)=O)C(O)=O

InChI

InChIKey=NOKPBJYHPHHWAN-REOHCLBHSA-N
InChI=1S/C3H7NO5S2/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H,7,8,9)/t2-/m0/s1

HIDE SMILES / InChI

Molecular Formula C3H7NO5S2
Molecular Weight 201.221
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
4.5 µM [EC50]
PubMed

PubMed

TitleDatePubMed
S-sulfocysteine/NMDA receptor-dependent signaling underlies neurodegeneration in molybdenum cofactor deficiency.
2017-12-01
Low abundance does not mean less importance in cysteine metabolism.
2010-08
S-sulfonation of transthyretin is an important trigger step in the formation of transthyretin-related amyloid fibril.
2010-07
Successful treatment of molybdenum cofactor deficiency type A with cPMP.
2010-05
Arabidopsis S-sulfocysteine synthase activity is essential for chloroplast function and long-day light-dependent redox control.
2010-02
Newborn with neonatal form of molybdenum cofactor deficiency - the first patient in the Slovak Republic.
2010
Molybdenum cofactor deficiency in a Malaysian child.
2009-10
Selective reversal of muscle relaxation in general anesthesia: focus on sugammadex.
2009-09-21
S-sulfo-cysteine is an endogenous amino acid in neonatal rat brain but an unlikely mediator of cysteine neurotoxicity.
2008-02
A spectroscopic investigation into the reaction of sodium tetrathionate with cysteine.
2008-01
The complete genome sequence and analysis of the epsilonproteobacterium Arcobacter butzleri.
2007-12-26
Secreted proteases from dermatophytes.
2007-10-15
Sulphite efflux pumps in Aspergillus fumigatus and dermatophytes.
2007-03
[Analysis of variant and modified structures of proteins by mass spectrometry--application for clinical laboratory test].
2006-09
Effective detection of peptides containing cysteine sulfonic acid using matrix-assisted laser desorption/ionization and laser desorption/ionization on porous silicon mass spectrometry.
2006-01
Molybdenum cofactor deficiency presenting as neonatal hyperekplexia: a clinical, biochemical and genetic study.
2005-12
Isolated sulphite oxidase deficiency mimics the features of hypoxic ischaemic encephalopathy.
2005-11
Isolated sulfite oxidase deficiency: a case report with a novel mutation and review of the literature.
2005-09
A conserved mechanism for sulfonucleotide reduction.
2005-08
Total truncation of the molybdopterin/dimerization domains of SUOX protein in an Arab family with isolated sulfite oxidase deficiency.
2005-07-15
Determination of urinary S-sulphocysteine, xanthine and hypoxanthine by liquid chromatography-electrospray tandem mass spectrometry.
2005-04
Effect of sulfite on cognitive function in normal and sulfite oxidase deficient rats.
2004-05-17
Modification of cysteine residue in transthyretin and a synthetic peptide: analyses by electrospray ionization mass spectrometry.
2004-04-08
Sulfur and selenium: the role of oxidation state in protein structure and function.
2003-10-13
A novel mutation in neonatal isolated sulphite oxidase deficiency.
2002-08
Ebselen has dehydroascorbate reductase and thioltransferase-like activities.
2002-03-01
Identification and characterization of a new mammalian glutaredoxin (thioltransferase), Grx2.
2001-08-10
Desensitization of NMDA receptor channels is modulated by glutamate agonists.
2001-05
Molybdenum cofactor deficiency: report of three cases presenting as hypoxic-ischemic encephalopathy.
2001-04
S-sulfonate determination and formation in meat products.
2001-01
Ahomocysteinemia in molybdenum cofactor deficiency.
1998-09
Molybdenum cofactor deficiency.
1993-10
Absence of hepatic molybdenum cofactor. An inborn error of metabolism associated with lens dislocation.
1985-04
2-Mercaptoethanesulfonate-cysteine disulfide excretion following the administration of 2-mercaptoethanesulfonate--a pitfall in the diagnosis of sulfite oxidase deficiency.
1981-03-19
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:55:48 GMT 2025
Edited
by admin
on Mon Mar 31 19:55:48 GMT 2025
Record UNII
885F2S42LL
Record Status Validated (UNII)
Record Version
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Name Type Language
S-SULFOCYSTEINE
Systematic Name English
ALANINETHIOSULFURIC ACID
Preferred Name English
S-CYSTEINESULFONIC ACID
Systematic Name English
L-CYSTEINESULFONIC ACID
Systematic Name English
L-CYSTEINE S-SULFATE
Systematic Name English
S-SULFO-L-CYSTEINE
Systematic Name English
L-CYSTEINE-S-SULFONATE
Common Name English
L-CYSTEINE, S-SULFO-
Systematic Name English
CYSTEINE-S-SULFONIC ACID
Common Name English
Code System Code Type Description
FDA UNII
885F2S42LL
Created by admin on Mon Mar 31 19:55:48 GMT 2025 , Edited by admin on Mon Mar 31 19:55:48 GMT 2025
PRIMARY
CAS
1637-71-4
Created by admin on Mon Mar 31 19:55:48 GMT 2025 , Edited by admin on Mon Mar 31 19:55:48 GMT 2025
PRIMARY
DRUG BANK
DB04370
Created by admin on Mon Mar 31 19:55:48 GMT 2025 , Edited by admin on Mon Mar 31 19:55:48 GMT 2025
PRIMARY
PUBCHEM
115015
Created by admin on Mon Mar 31 19:55:48 GMT 2025 , Edited by admin on Mon Mar 31 19:55:48 GMT 2025
PRIMARY
CHEBI
62225
Created by admin on Mon Mar 31 19:55:48 GMT 2025 , Edited by admin on Mon Mar 31 19:55:48 GMT 2025
PRIMARY
EPA CompTox
DTXSID20167649
Created by admin on Mon Mar 31 19:55:48 GMT 2025 , Edited by admin on Mon Mar 31 19:55:48 GMT 2025
PRIMARY
CHEBI
27891
Created by admin on Mon Mar 31 19:55:48 GMT 2025 , Edited by admin on Mon Mar 31 19:55:48 GMT 2025
PRIMARY