S-SULFOCYSTEINE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C3H7NO5S2
Molecular Weight	201.221
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

N[C@@H](CSS(O)(=O)=O)C(O)=O

InChI

InChIKey=NOKPBJYHPHHWAN-REOHCLBHSA-N

InChI=1S/C3H7NO5S2/c4-2(3(5)6)1-10-11(7,8)9/h2H,1,4H2,(H,5,6)(H,7,8,9)/t2-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C3H7NO5S2
Molecular Weight	201.221
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Glutamate NMDA receptor 46 Target ID: CHEMBL1907608 Sources: https://www.ncbi.nlm.nih.gov/pubmed/29106383 \| https://www.ncbi.nlm.nih.gov/pubmed/11325718	Agonist 2678		4.5 µM [EC50]

PubMed

Title	Date	PubMed
2-Mercaptoethanesulfonate-cysteine disulfide excretion following the administration of 2-mercaptoethanesulfonate--a pitfall in the diagnosis of sulfite oxidase deficiency.	1981 Mar 19	6784974
Absence of hepatic molybdenum cofactor. An inborn error of metabolism associated with lens dislocation.	1985 Apr	3877898
Molybdenum cofactor deficiency.	1993 Oct	8410516
Ahomocysteinemia in molybdenum cofactor deficiency.	1998 Sep	9748040
Molybdenum cofactor deficiency: report of three cases presenting as hypoxic-ischemic encephalopathy.	2001 Apr	11332461
Identification and characterization of a new mammalian glutaredoxin (thioltransferase), Grx2.	2001 Aug 10	11397793
S-sulfonate determination and formation in meat products.	2001 Jan	11170608
Desensitization of NMDA receptor channels is modulated by glutamate agonists.	2001 May	11325718
A novel mutation in neonatal isolated sulphite oxidase deficiency.	2002 Aug	12368985
Ebselen has dehydroascorbate reductase and thioltransferase-like activities.	2002 Mar 1	11855823
Sulfur and selenium: the role of oxidation state in protein structure and function.	2003 Oct 13	14562341
A conserved mechanism for sulfonucleotide reduction.	2005 Aug	16008502
Effect of sulfite on cognitive function in normal and sulfite oxidase deficient rats.	2005 Jan-Feb	15681120
Total truncation of the molybdopterin/dimerization domains of SUOX protein in an Arab family with isolated sulfite oxidase deficiency.	2005 Jul 15	15952210
Isolated sulphite oxidase deficiency mimics the features of hypoxic ischaemic encephalopathy.	2005 Nov	16025295
Isolated sulfite oxidase deficiency: a case report with a novel mutation and review of the literature.	2005 Sep	16140720
Effective detection of peptides containing cysteine sulfonic acid using matrix-assisted laser desorption/ionization and laser desorption/ionization on porous silicon mass spectrometry.	2006 Jan	16382481
[Analysis of variant and modified structures of proteins by mass spectrometry--application for clinical laboratory test].	2006 Sep	17063874
Sulphite efflux pumps in Aspergillus fumigatus and dermatophytes.	2007 Mar	17322211
S-sulfo-cysteine is an endogenous amino acid in neonatal rat brain but an unlikely mediator of cysteine neurotoxicity.	2008 Feb	17764028
Molybdenum cofactor deficiency in a Malaysian child.	2009 Oct	19907877
Selective reversal of muscle relaxation in general anesthesia: focus on sugammadex.	2009 Sep 21	19920928
Newborn with neonatal form of molybdenum cofactor deficiency - the first patient in the Slovak Republic.	2010	21187823
Low abundance does not mean less importance in cysteine metabolism.	2010 Aug	20699647
Successful treatment of molybdenum cofactor deficiency type A with cPMP.	2010 May	20385644
S-sulfocysteine/NMDA receptor-dependent signaling underlies neurodegeneration in molybdenum cofactor deficiency.	2017 Dec 1	29106383

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:44:49 GMT 2023` Edited by `admin` on `Fri Dec 15 19:44:49 GMT 2023`
Record UNII	885F2S42LL
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

S-SULFOCYSTEINE

Systematic Name

English

S-CYSTEINESULFONIC ACID

Systematic Name

English

L-CYSTEINESULFONIC ACID

Systematic Name

English

L-CYSTEINE S-SULFATE

Systematic Name

English

S-SULFO-L-CYSTEINE

Systematic Name

English

L-CYSTEINE-S-SULFONATE

Common Name

English

L-CYSTEINE, S-SULFO-

Systematic Name

English

CYSTEINE-S-SULFONIC ACID

Common Name

English

ALANINETHIOSULFURIC ACID

Common Name

English

Code System Code Type Description

FDA UNII

885F2S42LL