SULFAETHOXYPYRIDAZINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H14N4O3S
Molecular Weight	294.33
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCOC1=NN=C(NS(=O)(=O)C2=CC=C(N)C=C2)C=C1

InChI

InChIKey=FFJIWWBSBCOKLS-UHFFFAOYSA-N

InChI=1S/C12H14N4O3S/c1-2-19-12-8-7-11(14-15-12)16-20(17,18)10-5-3-9(13)4-6-10/h3-8H,2,13H2,1H3,(H,14,16)

HIDE SMILES / InChI

Molecular Formula	C12H14N4O3S
Molecular Weight	294.33
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5888505 | https://www.ncbi.nlm.nih.gov/pubmed/5963854

Sulfaethoxypyridazine an antibacterial sulfonamide compound. It is veterinary use only against bacterial infections, such as fowl cholera and salmonella infection.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Bacterial infections 234 Sources: https://www.ncbi.nlm.nih.gov/pubmed/5831049	Curative		Approved 8429	SEZ Approved Use Approved only for veterinary use in domestic animals and birds

PubMed

Title	Date	PubMed
The pharmacology of sulfaethoxypyridazine in the heifer.	1965 Aug	5831049
Efficacy of sulfaethoxypyridazine against fowl cholera in artificially infected chickens and turkeys, and its safety in laying chickens and broilers.	1966 May	5963854
Development of cataracts in dogs and rats from prolonged feeding of sulfaethoxypyridazine.	1967 May	6059670
Sulfaethoxypyridazine: an evaluation in swine.	1969 Jan	5189754
Effect of water deprivation and forced exercise on blood concentrations of sulfaethoxypyridazine after its oral administration to calves.	1973 Oct 1	4777299
Determination of sulfonamide residues in the tissues of food animals using automated precolumn derivatization and liquid chromatography with fluorescence detection.	2004 Sep-Oct	15493686
Chemical genomic profiling for antimalarial therapies, response signatures, and molecular targets.	2011 Aug 5	21817045

Patents

Sample Use Guides

In Vivo Use Guide

Heifers were treated with a single dose (25 mg/lb body weight) of sulfaethoxypyridazine by intravenous and oral routes.

Route of Administration: Other

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:08:12 GMT 2023` Edited by `admin` on `Fri Dec 15 16:08:12 GMT 2023`
Record UNII	880RIW1DED
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SULFAETHOXYPYRIDAZINE

Common Name

English

4-AMINO-N-(6-ETHOXY-3-PYRIDAZINYL)BENZENESULFONAMIDE

Systematic Name

English

SULFAETHOXYPYRIDAZINE [GREEN BOOK]

Common Name

English

6-ETHOXY-3-SULFANILAMIDOPYRIDAZINE

Systematic Name

English

Classification Tree Code System Code

CFR

21 CFR 520.2240B