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Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Mon Mar 31 22:57:17 GMT 2025
Edited
by admin
on Mon Mar 31 22:57:17 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
87T4327873
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
REGN-1033
Preferred Name English
TREVOGRUMAB
INN   USAN   WHO-DD  
INN   USAN  
Official Name English
HUMAN MONOCLONAL ANTIBODY TO GDF8 (MYOSTATIN)
Common Name English
HUMAN IGG4 TYPE MONOCLONAL ANTIBODY TO GDF8 (MYOSTATIN)
Common Name English
TREVOGRUMAB [USAN]
Common Name English
IMMUNOGLOBULIN, ANTI-(HUMAN GROWTH DIFFERENTIATION FACTOR 8) (HUMAN REGN1033 HEAVY CHAIN), DISULFIDE WITH HUMAN REGN1033 .KAPPA.-CHAIN, DIMER
Systematic Name English
REGN1033
Code English
SAR-391786
Code English
SAR391786
Code English
Trevogrumab [WHO-DD]
Common Name English
HUMAN IGG4 ANTI-MYOSTATIN MAB
Common Name English
trevogrumab [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C20401
Created by admin on Mon Mar 31 22:57:17 GMT 2025 , Edited by admin on Mon Mar 31 22:57:17 GMT 2025
EU-Orphan Drug EU/3/13/1105
Created by admin on Mon Mar 31 22:57:17 GMT 2025 , Edited by admin on Mon Mar 31 22:57:17 GMT 2025
Code System Code Type Description
INN
10087
Created by admin on Mon Mar 31 22:57:17 GMT 2025 , Edited by admin on Mon Mar 31 22:57:17 GMT 2025
PRIMARY
SMS_ID
300000021901
Created by admin on Mon Mar 31 22:57:17 GMT 2025 , Edited by admin on Mon Mar 31 22:57:17 GMT 2025
PRIMARY
WIKIPEDIA
Trevogrumab
Created by admin on Mon Mar 31 22:57:17 GMT 2025 , Edited by admin on Mon Mar 31 22:57:17 GMT 2025
PRIMARY
FDA UNII
87T4327873
Created by admin on Mon Mar 31 22:57:17 GMT 2025 , Edited by admin on Mon Mar 31 22:57:17 GMT 2025
PRIMARY
ChEMBL
CHEMBL3545374
Created by admin on Mon Mar 31 22:57:17 GMT 2025 , Edited by admin on Mon Mar 31 22:57:17 GMT 2025
PRIMARY
DRUG BANK
DB15159
Created by admin on Mon Mar 31 22:57:17 GMT 2025 , Edited by admin on Mon Mar 31 22:57:17 GMT 2025
PRIMARY
CAS
1429201-24-0
Created by admin on Mon Mar 31 22:57:17 GMT 2025 , Edited by admin on Mon Mar 31 22:57:17 GMT 2025
PRIMARY
ChEMBL
CHEMBL2109645
Created by admin on Mon Mar 31 22:57:17 GMT 2025 , Edited by admin on Mon Mar 31 22:57:17 GMT 2025
PRIMARY
NCI_THESAURUS
C152733
Created by admin on Mon Mar 31 22:57:17 GMT 2025 , Edited by admin on Mon Mar 31 22:57:17 GMT 2025
PRIMARY
USAN
AB-142
Created by admin on Mon Mar 31 22:57:17 GMT 2025 , Edited by admin on Mon Mar 31 22:57:17 GMT 2025
PRIMARY
From To
1_22 1_96
1_134 3_214
1_147 1_203
1_226 2_226
1_229 2_229
1_261 1_321
1_367 1_425
2_22 2_96
2_134 4_214
2_147 2_203
2_261 2_321
2_367 2_425
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_297
N 2_297
Related Record Type Details
MYOSTATIN
TARGET -> INHIBITOR
Related Record Type Details
TREVOGRUMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:SEQUENCE(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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