FROVOCIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 21:49:48 GMT 2025` Edited by `admin` on `Mon Mar 31 21:49:48 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMANIZED
Sequence Type	COMPLETE
Record UNII	87PZ955YRB
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

FROVOCIMAB

Official Name

English

LY-3015014

Preferred Name

English

LY3015014

Code

English

IMMUNOGLOBULIN G4, ANTI-(PROPROTEIN CONVERTASE SUBTILISIN KEXIN 9(PCSK9))(HUMAN MONOCLONAL LY3015014 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL LY3015014 LIGHT-CHAIN, DIMER

Systematic Name

English

FROVOCIMAB [USAN]

Common Name

English

Frovocimab [WHO-DD]

Common Name

English

IMMUNOGLOBULIN G4-KAPPA, ANTI-(HUMAN PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (NEURAL APOPTOSIS-REGULATED CONVERTASE 1, PROPROTEIN CONVERTASE 9, SUBTILISIN/KEXIN-LIKE PROTEASE PC9, EC=3.4.21.-))HUMANIZED MONOCLONAL ANTIBODY.GAMMA.4 HEAVY CHAIN (1-45

Systematic Name

English

frovocimab [INN]

Common Name

English

Code System Code Type Description

CAS

1643672-70-1

Created by admin on Mon Mar 31 21:49:48 GMT 2025 , Edited by admin on Mon Mar 31 21:49:48 GMT 2025

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FDA UNII

87PZ955YRB

Created by admin on Mon Mar 31 21:49:48 GMT 2025 , Edited by admin on Mon Mar 31 21:49:48 GMT 2025

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USAN

EF-59

Created by admin on Mon Mar 31 21:49:48 GMT 2025 , Edited by admin on Mon Mar 31 21:49:48 GMT 2025

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INN

10859

Created by admin on Mon Mar 31 21:49:48 GMT 2025 , Edited by admin on Mon Mar 31 21:49:48 GMT 2025

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NCI_THESAURUS

C175068

Created by admin on Mon Mar 31 21:49:48 GMT 2025 , Edited by admin on Mon Mar 31 21:49:48 GMT 2025

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DRUG BANK

DB15089

Created by admin on Mon Mar 31 21:49:48 GMT 2025 , Edited by admin on Mon Mar 31 21:49:48 GMT 2025

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SMS_ID

100000183542

Created by admin on Mon Mar 31 21:49:48 GMT 2025 , Edited by admin on Mon Mar 31 21:49:48 GMT 2025

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Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_302
N	2_302

Related Record Type Details


					LGW95S5DG1

PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9

TARGET -> INHIBITOR

Interaction Type:

BINDING

Amount:

Related Record Type Details


					87PZ955YRB

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS			PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NON-GLYCOSYLATED(CALCULATED)	CHEMICAL