THIOBENZAMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H7NS
Molecular Weight	137.202
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC(=S)C1=CC=CC=C1

InChI

InChIKey=QIOZLISABUUKJY-UHFFFAOYSA-N

InChI=1S/C7H7NS/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9)

HIDE SMILES / InChI

Molecular Formula	C7H7NS
Molecular Weight	137.202
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Formation of covalently bound protein adducts from the cytotoxicant naphthalene in nasal epithelium: species comparisons.	2010-05	20435546
Cytotoxic activity of 3-(5-phenyl-3H-[1,2,4]dithiazol-3-yl)chromen-4-ones and 4-oxo-4H-chromene-3-carbothioic acid N-phenylamides.	2010-02	19939522
ETM-ANN approach application for thiobenzamide and quinolizidine derivatives.	2010	20871848
Mechanism of unusual formation of 3-(5-phenyl-3H-[1,2,4]dithiazol-3-yl)chromen-4-ones and 4-oxo-4H-chromene-3-carbothioic acid N-phenylamides and their antimicrobial evaluation.	2009-08	19375826
Bioinformatic analysis of xenobiotic reactive metabolite target proteins and their interacting partners.	2009-06-12	19523227
Hexa-thiocarbamoyl phenyl PEG5K Hb: vasoactivity and structure: influence of rigidity of the conjugation linkage on the PEGylation induced plasma expander-like solution properties of PEG-Hb adducts.	2009-06	19653083
The investigation of structure-activity relationships of tacrine analogues: electronic-topological method.	2008-08-06	19662147
Enantiomeric resolution of N,N'-dimethyldithiodianthranilide through diastereomeric silver(I) complex. Circular dichroism spectra, racemization barrier, and molecular self-assembly.	2008-07-04	18510365
Chemical Research in Toxicology. In this issue.	2008-07	18637700
Protein targets of reactive metabolites of thiobenzamide in rat liver in vivo.	2008-07	18547066
Hydrogen sulfide enhances ulcer healing in rats.	2007-12	17634391
Conformational polymorphism in N-(4'-methoxyphenyl)- 3-bromothiobenzamide.	2007-04-02	17441191
Covalent modification of microsomal lipids by thiobenzamide metabolites in vivo.	2007-04	17381136
The reactive metabolite target protein database (TPDB)--a web-accessible resource.	2007-03-16	17367530
A proteomic analysis of bromobenzene reactive metabolite targets in rat liver cytosol in vivo.	2007-03	17305373
Flavin-containing monooxygenase activity can be inhibited by nitric oxide-mediated S-nitrosylation.	2004-10-08	15363661
Planar chiral dianthranilide and dithiodianthranilide molecules: optical resolution, chiroptical spectra, and molecular self-assembly.	2004-02-20	14961677
Rat breast microsomal biotransformation of ethanol to acetaldehyde but not to free radicals: its potential role in the association between alcohol drinking and breast tumor promotion.	2003	12616597
Structure-activity relationships for a series of thiobenzamide influenza fusion inhibitors derived from 1,3,3-trimethyl-5-hydroxy-cyclohexylmethylamine.	2002-12-02	12419365
The antituberculosis drug ethionamide is activated by a flavoprotein monooxygenase.	2002-04-12	11823459
Synthesis of 1,3-thiazine derivatives and their evaluation as potential antimycobacterial agents.	2002-04	11923063
Rat ventral prostate microsomal biotransformation of ethanol to acetaldehyde and 1-hydroxyethyl radicals: its potential contribution to prostate tumor promotion.	2002	12210496
[Chemical studies the mechanism of action of isoniazid].	1966-11	4234663

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:11:51 GMT 2025` Edited by `admin` on `Mon Mar 31 19:11:51 GMT 2025`
Record UNII	8799VM9SXC
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

BENZOTHIOAMIDE

Preferred Name

English

THIOBENZAMIDE

Systematic Name

English

Code System Code Type Description

EPA CompTox

DTXSID8062280