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Details

Stereochemistry ACHIRAL
Molecular Formula CH5N3O
Molecular Weight 75.0699
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of HYDROXYGUANIDINE

SMILES

NC(=N)NO

InChI

InChIKey=WFBHRSAKANVBKH-UHFFFAOYSA-N
InChI=1S/CH5N3O/c2-1(3)4-5/h5H,(H4,2,3,4)

HIDE SMILES / InChI

Molecular Formula CH5N3O
Molecular Weight 75.0699
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
EPR and ENDOR characterization of intermediates in the cryoreduced oxy-nitric oxide synthase heme domain with bound L-arginine or N(G)-hydroxyarginine.
2002 Aug 20
Ceramide binding to African-American hair fibre correlates with resistance to hair breakage.
2002 Feb
Novel substrates for nitric oxide synthases.
2002 Sep
[Metalloporphyrin catalyzed biomimetic oxidation potentials: potential uses and applications].
2003
Two modes of binding of N-hydroxyguanidines to NO synthases: first evidence for the formation of iron-N-hydroxyguanidine complexes and key role of tetrahydrobiopterin in determining the binding mode.
2003 Apr 8
pH-dependent stability of sperm whale myoglobin in water-guanidine hydrochloride solutions.
2003 Feb
The mechanism of L-canavanine cytotoxicity: arginyl tRNA synthetase as a novel target for anticancer drug discovery.
2003 Oct
Reactivity of the heme-dioxygen complex of the inducible nitric oxide synthase in the presence of alternative substrates.
2006 Jan
Identification of non-peptidic neuromedin U receptor modulators by a robust homogeneous screening assay.
2008 Apr
Synthesis of (+)- and (-)-monanchorin.
2009 Feb 19
N-Hydroxyguanidines oxidation by a N3S copper-complex mimicking the reactivity of Dopamine beta-Hydroxylase.
2009 Mar
Reaction of N-hydroxyguanidine with the ferrous-oxy state of a heme peroxidase cavity mutant: a model for the reactions of nitric oxide synthase.
2010 Aug 1
Discovery and clinical evaluation of 1-{N-[2-(amidinoaminooxy)ethyl]amino}carbonylmethyl-6-methyl-3-[2,2-difluoro-2-phenylethylamino]pyrazinone (RWJ-671818), a thrombin inhibitor with an oxyguanidine P1 motif.
2010 Feb 25
Dimerization of protegrin-1 in different environments.
2010 Sep 9
Substance Class Chemical
Created
by admin
on Fri Dec 15 18:12:19 GMT 2023
Edited
by admin
on Fri Dec 15 18:12:19 GMT 2023
Record UNII
8767F421T7
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
HYDROXYGUANIDINE
Common Name English
N-HYDROXYGUANIDINE
Systematic Name English
NSC-529357
Code English
UREA, OXIME
Common Name English
N''-HYDROXYGUANIDINE
Systematic Name English
GUANIDINE, HYDROXY-
Systematic Name English
Code System Code Type Description
NSC
529357
Created by admin on Fri Dec 15 18:12:19 GMT 2023 , Edited by admin on Fri Dec 15 18:12:19 GMT 2023
PRIMARY
CHEBI
43089
Created by admin on Fri Dec 15 18:12:19 GMT 2023 , Edited by admin on Fri Dec 15 18:12:19 GMT 2023
PRIMARY
DRUG BANK
DB03770
Created by admin on Fri Dec 15 18:12:19 GMT 2023 , Edited by admin on Fri Dec 15 18:12:19 GMT 2023
PRIMARY
EPA CompTox
DTXSID00156915
Created by admin on Fri Dec 15 18:12:19 GMT 2023 , Edited by admin on Fri Dec 15 18:12:19 GMT 2023
PRIMARY
PUBCHEM
80668
Created by admin on Fri Dec 15 18:12:19 GMT 2023 , Edited by admin on Fri Dec 15 18:12:19 GMT 2023
PRIMARY
FDA UNII
8767F421T7
Created by admin on Fri Dec 15 18:12:19 GMT 2023 , Edited by admin on Fri Dec 15 18:12:19 GMT 2023
PRIMARY
CAS
13115-21-4
Created by admin on Fri Dec 15 18:12:19 GMT 2023 , Edited by admin on Fri Dec 15 18:12:19 GMT 2023
PRIMARY