PHCCC

Details

Stereochemistry	RACEMIC
Molecular Formula	C17H14N2O3
Molecular Weight	294.3047
Optical Activity	( + / - )
Defined Stereocenters	2 / 2
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O\N=C1/[C@H]2C[C@]2(OC3=C1C=CC=C3)C(=O)NC4=CC=CC=C4

InChI

InChIKey=FPXPIEZPAXSELW-REIIWYCASA-N

InChI=1S/C17H14N2O3/c20-16(18-11-6-2-1-3-7-11)17-10-13(17)15(19-21)12-8-4-5-9-14(12)22-17/h1-9,13,21H,10H2,(H,18,20)/b19-15-/t13-,17-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C17H14N2O3
Molecular Weight	294.3047
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	1
Optical Activity	UNSPECIFIED

Approval Year

Targets

Primary Target	Pharmacology	Potency
Metabotropic glutamate receptor 6 6 Target ID: CHEMBL3842 Sources: https://www.ncbi.nlm.nih.gov/pubmed/18593581	Positive Allosteric Modulator 186	4.8 null [pEC50]
Metabotropic glutamate receptor 4 5 Target ID: CHEMBL2736 Sources: https://www.ncbi.nlm.nih.gov/pubmed/14573382 \| https://www.ncbi.nlm.nih.gov/pubmed/23098651	Positive Allosteric Modulator 186	3.8 µM [EC50]
Metabotropic glutamate receptor 1 25 Target ID: CHEMBL3772 Sources: https://www.ncbi.nlm.nih.gov/pubmed/14573382	Antagonist 2849	3.4 µM [IC50]
Metabotropic glutamate receptor 4 5 Target ID: CHEMBL2736 Sources: https://www.ncbi.nlm.nih.gov/pubmed/14593202	Positive Allosteric Modulator 186	4.5 null [pEC50]
Metabotropic glutamate receptor 6 6 Target ID: CHEMBL4573 Sources: https://www.ncbi.nlm.nih.gov/pubmed/18593581	Positive Allosteric Modulator 186	4.8 null [pEC50]

Substance Class	Chemical Created by `admin` on `Wed Apr 02 10:46:14 GMT 2025` Edited by `admin` on `Wed Apr 02 10:46:14 GMT 2025`
Record UNII	875PGG7NBA
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

7,7A-DIHYDRO-7-(HYDROXYIMINO)-N-PHENYLBENZO(B)CYCLOPROPA(E)PYRAN-1A(1H)-CARBOXAMIDE

Preferred Name

English

PHCCC

Common Name

English

BENZO(B)CYCLOPROPA(E)PYRAN-1A(1H)-CARBOXAMIDE, 7,7A-DIHYDRO-7-(HYDROXYIMINO)-N-PHENYL-

Systematic Name

English

N-PHENYL-7-(HYDROXYIMINO)CYCLOPROPA(B)CHROMEN-1A-CARBOXAMIDE

Systematic Name

English

BENZO(B)CYCLOPROPA(E)PYRAN-1A(1H)-CARBOXAMIDE, 7,7A-DIHYDRO-7-(HYDROXYIMINO)-N-PHENYL-, (E)-

Systematic Name

English

Code System Code Type Description

CAS

179068-02-1

Created by admin on Wed Apr 02 10:46:14 GMT 2025 , Edited by admin on Wed Apr 02 10:46:14 GMT 2025

NON-SPECIFIC STEREOCHEMISTRY

EPA CompTox

DTXSID501028472

Created by admin on Wed Apr 02 10:46:14 GMT 2025 , Edited by admin on Wed Apr 02 10:46:14 GMT 2025

PRIMARY

CAS

177610-87-6

Created by admin on Wed Apr 02 10:46:14 GMT 2025 , Edited by admin on Wed Apr 02 10:46:14 GMT 2025

PRIMARY

FDA UNII

875PGG7NBA

Created by admin on Wed Apr 02 10:46:14 GMT 2025 , Edited by admin on Wed Apr 02 10:46:14 GMT 2025

PRIMARY

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Amount: