MF-766

Details

Stereochemistry	ACHIRAL
Molecular Formula	C27H21F3N2O3
Molecular Weight	478.4624
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)C1=CC=C(C=C1)C2(CC2)NC(=O)C3=CC=CC4=C3N(CC5=CC=C(C=C5)C(F)(F)F)C=C4

InChI

InChIKey=BWXAZFCPGFKANL-UHFFFAOYSA-N

InChI=1S/C27H21F3N2O3/c28-27(29,30)21-8-4-17(5-9-21)16-32-15-12-18-2-1-3-22(23(18)32)24(33)31-26(13-14-26)20-10-6-19(7-11-20)25(34)35/h1-12,15H,13-14,16H2,(H,31,33)(H,34,35)

HIDE SMILES / InChI

Molecular Formula	C27H21F3N2O3
Molecular Weight	478.4624
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Discovery of 4-[1-[([1-[4-(trifluoromethyl)benzyl]-1H-indol-7-yl]carbonyl)amino]cyclopropyl]benzoic acid (MF-766), a highly potent and selective EP4 antagonist for treating inflammatory pain.	2010-06-15	20471829

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:20:17 GMT 2025` Edited by `admin` on `Mon Mar 31 18:20:17 GMT 2025`
Record UNII	86KF5VSV88
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

BENZOIC ACID, 4-(1-(((1-((4-(TRIFLUOROMETHYL)PHENYL)METHYL)-1H-INDOL-7-YL)CARBONYL)AMINO)CYCLOPROPYL)-

Preferred Name

English

MF-766

Common Name

English

Code System Code Type Description

PUBCHEM

25003075

Created by admin on Mon Mar 31 18:20:17 GMT 2025 , Edited by admin on Mon Mar 31 18:20:17 GMT 2025

PRIMARY

CAS

1050656-06-8

Created by admin on Mon Mar 31 18:20:17 GMT 2025 , Edited by admin on Mon Mar 31 18:20:17 GMT 2025

PRIMARY

FDA UNII

86KF5VSV88

Created by admin on Mon Mar 31 18:20:17 GMT 2025 , Edited by admin on Mon Mar 31 18:20:17 GMT 2025

PRIMARY

Related Record Type Details


					86KF5VSV88

MF-766

ACTIVE MOIETY