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Details

Stereochemistry ACHIRAL
Molecular Formula C6H12N4O2
Molecular Weight 172.1851
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of DIAMIDE

SMILES

CN(C)C(=O)\N=N\C(=O)N(C)C

InChI

InChIKey=VLSDXINSOMDCBK-BQYQJAHWSA-N
InChI=1S/C6H12N4O2/c1-9(2)5(11)7-8-6(12)10(3)4/h1-4H3/b8-7+

HIDE SMILES / InChI
Molecular Formula C6H12N4O2
Molecular Weight 172.1851
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE

Approval Year

Unknown
149124
PubMed

PubMed

TitleDatePubMed
Involvement of riboflavin kinase expression in cellular sensitivity against cisplatin.
2011-04
Clusterin (apolipoprotein J), a molecular chaperone that facilitates degradation of the copper-ATPases ATP7A and ATP7B.
2011-03-25
Effect of protein S-glutathionylation on Ca2+ homeostasis in cultured aortic endothelial cells.
2011-02
Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents.
2009-06-15
Human p53 is inhibited by glutathionylation of cysteines present in the proximal DNA-binding domain during oxidative stress.
2007-07-03
Redox regulation of human OGG1 activity in response to cellular oxidative stress.
2006-10
Hydrogen peroxide and redox modulation sensitize primary mouse hepatocytes to TNF-induced apoptosis.
2006-08-15
Redox regulation of the nutrient-sensitive raptor-mTOR pathway and complex.
2005-11-25
Activating cystic fibrosis transmembrane conductance regulator channels with pore blocker analogs.
2005-06-24
Spatial activities and induction of glutamate-cysteine ligase (GCL) in the postimplantation rat embryo and visceral yolk sac.
2004-10
Interaction of selenium compounds with zinc finger proteins involved in DNA repair.
2004-08
Reversible inactivation of alpha-ketoglutarate dehydrogenase in response to alterations in the mitochondrial glutathione status.
2003-04-15
Differential inhibitory action of two azoic compounds against arenaviruses.
2003-04
p38 MAP kinase mediates stress-induced leukotriene synthesis in a human B-lymphocyte cell line.
2001-11
Oxidative stress triggers STAT3 tyrosine phosphorylation and nuclear translocation in human lymphocytes.
1999-06-18
Redox regulation of manganese superoxide dismutase.
1996-07
Thiol modulation of TNF alpha and IL-1 induced MnSOD gene expression and activation of NF-kappa B.
1995-07-05
Patents

Patents

JP1069649A
1
JP1071858A
2
JP2000017161A
1
JP2000038450A
1
JP2000072604A
1
JP2000239378A
1
JP2000239419A
2
JP2000248176A
6
JP2000328095A
2
JP2001158764A
1
JP2001207186A
1
JP2001240580A
1
JP2002047261A
1
JP2002088038A
1
JP2002114666A
2
JP2002146336A
1
JP2002201183A
1
JP2002201352A
1
JP2002326980A
1
JP2002332208A
1
JP2002523384A
2
JP2002527555A
5
JP2003012464A
1
JP2003012465A
1
JP2003012474A
2
JP2003020492A
1
JP2003176831A
1
JP2003232450A
1
JP2003238815A
1
JP2003327515A
1
JP2003327516A
1
JP2003327519A
1
JP2004075668A
1
JP2004107543A
1
JP2004108442A
1
JP2004210716A
1
JP2004224727A
1
JP2004231653A
1
JP2004255166A
1
JP2004262809A
1
JP2004505009A
8
JP2005035982A
1
JP2005139076A
1
JP2005139154A
1
JP2005139155A
1
JP2005306886A
1
JP2005343861A
1
JP2005504063A
1
JP2008031082A
2
JP2008056766A
1
JP2008169153A
1
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:53:05 GMT 2025
Edited
by admin
on Mon Mar 31 19:53:05 GMT 2025
Record UNII
86EQC90W32
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NSC-143013
Preferred Name English
DIAMIDE
Common Name English
N,N,N',N'-TETRAMETHYLAZODICARBOXAMIDE
Systematic Name English
1,1'-AZOBIS(N,N-DIMETHYLFORMAMIDE)
Systematic Name English
Code System Code Type Description
SMS_ID
300000023398
Created by admin on Mon Mar 31 19:53:05 GMT 2025 , Edited by admin on Mon Mar 31 19:53:05 GMT 2025
PRIMARY
CAS
10465-78-8
Created by admin on Mon Mar 31 19:53:05 GMT 2025 , Edited by admin on Mon Mar 31 19:53:05 GMT 2025
PRIMARY
PUBCHEM
5353800
Created by admin on Mon Mar 31 19:53:05 GMT 2025 , Edited by admin on Mon Mar 31 19:53:05 GMT 2025
PRIMARY
ECHA (EC/EINECS)
233-951-7
Created by admin on Mon Mar 31 19:53:05 GMT 2025 , Edited by admin on Mon Mar 31 19:53:05 GMT 2025
PRIMARY
NSC
143013
Created by admin on Mon Mar 31 19:53:05 GMT 2025 , Edited by admin on Mon Mar 31 19:53:05 GMT 2025
PRIMARY
CHEBI
48958
Created by admin on Mon Mar 31 19:53:05 GMT 2025 , Edited by admin on Mon Mar 31 19:53:05 GMT 2025
PRIMARY
EPA CompTox
DTXSID6040456
Created by admin on Mon Mar 31 19:53:05 GMT 2025 , Edited by admin on Mon Mar 31 19:53:05 GMT 2025
PRIMARY
FDA UNII
86EQC90W32
Created by admin on Mon Mar 31 19:53:05 GMT 2025 , Edited by admin on Mon Mar 31 19:53:05 GMT 2025
PRIMARY
WIKIPEDIA
Tetramethylazodicarboxamide
Created by admin on Mon Mar 31 19:53:05 GMT 2025 , Edited by admin on Mon Mar 31 19:53:05 GMT 2025
PRIMARY
MESH
D003958
Created by admin on Mon Mar 31 19:53:05 GMT 2025 , Edited by admin on Mon Mar 31 19:53:05 GMT 2025
PRIMARY
NIH
NCATS
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