U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 17:11:11 GMT 2023
Edited
by admin
on Sat Dec 16 17:11:11 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
86780VJI1Q
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Patritumab
INN   WHO-DD  
USAN   INN  
Official Name English
Immunoglobulin G1, anti-(human neuregulin receptor HER3) (human monoclonal U3-1287 heavy chain), disulfide with human monoclonal U3-1287 κ-chain, dimer
Common Name English
PATRITUMAB [USAN]
Common Name English
Patritumab [WHO-DD]
Common Name English
AMG-888
Code English
AMG888
Code English
patritumab [INN]
Common Name English
U-31287
Code English
U3-1287
Code English
Immunoglobulin G1-kappa, anti-[Homo sapiens ERBB3 (receptor tyrosine-protein kinase erbB-3, HER3)], Homo sapiens monoclonal antibody; gamma1 heavy chain (1-447) [Homo sapiens VH (IGHV4-34*01 (99.00%) -(IGHD)-IGHJ2*01) [8.7.11] (1-117) -IGHG1*03 (118-447)
Common Name English
U31287
Code English
Classification Tree Code System Code
NCI_THESAURUS C20401
Created by admin on Sat Dec 16 17:11:12 GMT 2023 , Edited by admin on Sat Dec 16 17:11:12 GMT 2023
Code System Code Type Description
ChEMBL
CHEMBL2109396
Created by admin on Sat Dec 16 17:11:12 GMT 2023 , Edited by admin on Sat Dec 16 17:11:12 GMT 2023
PRIMARY
ChEMBL
CHEMBL2109406
Created by admin on Sat Dec 16 17:11:12 GMT 2023 , Edited by admin on Sat Dec 16 17:11:12 GMT 2023
PRIMARY
CAS
1361109-68-3
Created by admin on Sat Dec 16 17:11:12 GMT 2023 , Edited by admin on Sat Dec 16 17:11:12 GMT 2023
ALTERNATIVE
CAS
1262787-83-6
Created by admin on Sat Dec 16 17:11:12 GMT 2023 , Edited by admin on Sat Dec 16 17:11:12 GMT 2023
PRIMARY
FDA UNII
86780VJI1Q
Created by admin on Sat Dec 16 17:11:12 GMT 2023 , Edited by admin on Sat Dec 16 17:11:12 GMT 2023
PRIMARY
USAN
KL-232
Created by admin on Sat Dec 16 17:11:12 GMT 2023 , Edited by admin on Sat Dec 16 17:11:12 GMT 2023
PRIMARY
INN
9549
Created by admin on Sat Dec 16 17:11:12 GMT 2023 , Edited by admin on Sat Dec 16 17:11:12 GMT 2023
PRIMARY
NCI_THESAURUS
C78853
Created by admin on Sat Dec 16 17:11:12 GMT 2023 , Edited by admin on Sat Dec 16 17:11:12 GMT 2023
PRIMARY
DRUG BANK
DB12090
Created by admin on Sat Dec 16 17:11:12 GMT 2023 , Edited by admin on Sat Dec 16 17:11:12 GMT 2023
PRIMARY
WIKIPEDIA
Patritumab
Created by admin on Sat Dec 16 17:11:12 GMT 2023 , Edited by admin on Sat Dec 16 17:11:12 GMT 2023
PRIMARY
From To
1_22 1_95
1_144 1_200
1_261 1_321
1_367 1_425
2_22 2_95
2_144 2_200
2_261 2_321
2_367 2_425
3_23 3_94
3_140 3_200
4_23 4_94
4_140 4_200
1_220 3_220
2_220 4_220
1_226 2_226
1_229 2_229
Glycosylation Link Type Site
N 1_297
N 2_297
Related Record Type Details
DERIVATIVE -> PARENT
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL