N-PHENYLUREA

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H8N2O
Molecular Weight	136.1512
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC(=O)NC1=CC=CC=C1

InChI

InChIKey=LUBJCRLGQSPQNN-UHFFFAOYSA-N

InChI=1S/C7H8N2O/c8-7(10)9-6-4-2-1-3-5-6/h1-5H,(H3,8,9,10)

HIDE SMILES / InChI

Molecular Formula	C7H8N2O
Molecular Weight	136.1512
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha) is expressed in resting murine lymphocytes. The PPARalpha in T and B lymphocytes is both transactivation and transrepression competent.	2002-03-01	11726654
Dihydropyridine neuropeptide Y Y(1) receptor antagonists.	2002-02-11	11814801
A(3) adenosine receptors in human neutrophils and promyelocytic HL60 cells: a pharmacological and biochemical study.	2002-02	11809867
Flufenoxuron, an insect growth regulator, promotes peroral infection by nucleopolyhedrovirus (BmNPV) budded particles in the silkworm, Bombyx mori L.	2002-02	11742661
Soil surface structure effect on isoproturon and diflufenican loss in runoff.	2002-01-16	11790021
A chemokine receptor CCR-1 antagonist reduces renal fibrosis after unilateral ureter ligation.	2002-01	11805137
Gastric acid secretion in L-histidine decarboxylase-deficient mice.	2002-01	11781289
Administration of two antagonists of the cholecystokinin(B)/gastrin receptor does not totally inhibit the pancreatic response to a meal in the pig.	2002-01	11741182
Template-constrained somatostatin analogues: a biphenyl linker induces a type-V' turn.	2001-12-19	11741449
Effects of cholecystokinin tetrapeptide (CCK(4)) and anxiolytic drugs on the electrically evoked [(3)H]5-hydroxytryptamine outflow from rat cortical slices.	2001-12-13	11730707
Penetration of herbicides to groundwater in an unconfined chalk aquifer following normal soil applications.	2001-12-01	11816989
Modulation of tetrodotoxin-resistant sodium channels by dihydropyrazole insecticide RH-3421 in rat dorsal root ganglion neurons.	2001-12	11829408
Influence of topsoil tilth and soil moisture status on losses of pesticide to drains from a heavy clay soil.	2001-12	11802600
Phototransformation of metoxuron [3-(3-chloro-4-methoxyphenyl)-1,1-dimethylurea] in aqueous solution.	2001-12	11802599
Effects of various insecticides on the development of the egg parasitoid Trichogramma dendrolimi (Hymenoptera: Trichogrammatidae).	2001-12	11777034
3-Benzamido, ureido and thioureidoimidazo[1,2-a]pyridine derivatives as potential antiviral agents.	2001-12	11767086
Isoproturon degradation as affected by the growth of two algal species at different concentrations and pH values.	2001-11	11757732
Quantitative structure-transformation relationships of phenylurea herbicides.	2001-11	11721522
Pharmacological and biochemical characterization of adenosine receptors in the human malignant melanoma A375 cell line.	2001-11	11704641
Effects of lectins on CCK-8-stimulated enzyme secretion and differentiation of the rat pancreatic cell line AR42J.	2001-11	11668205
Microbial inhibitors for U.S. EPA drinking water methods for the determination of organic compounds.	2001-10-15	11686373
Pharmacological analysis of wine-stimulated gastric acid secretion in dogs.	2001-10-12	11595441
Quantification of dissolved natural organic matter (DOM) mediated phototransformation of phenylurea herbicides in lakes.	2001-10-01	11642452
How to overcome matrix effects in the determination of pesticides in fruit by HPLC-ESI-MS-MS.	2001-10	11760068
Mitogenic effect of gastrin and expression of gastrin receptors in duct-like cells of rat pancreas.	2001-10	11606507
Formation of volatile halogenated by-products during chlorination of isoproturon aqueous solutions.	2001-10	11592415
Nonpeptide CXCR2 antagonist prevents neutrophil accumulation in hyperoxia-exposed newborn rats.	2001-10	11561067
Determination of phenylurea herbicides in natural waters at concentrations below 1 ng l(-1) using solid-phase extraction, derivatization, and solid-phase microextraction-gas chromatography-mass spectrometry.	2001-09-28	11681583
Evidence that ligand and metal ion binding to integrin alpha 4beta 1 are regulated through a coupled equilibrium.	2001-09-28	11473127
Identification of CCK-B/gastrin receptor splice variants in human peripheral blood mononuclear cells.	2001-09-15	11495676
Induction and inactivation of a cytochrome P450 confering herbicide resistance in wheat seedlings.	2001-09-14	11554440
The characterization of PPAR alpha ligand drug action in an in vivo model by comprehensive differential gene expression profiling.	2001-09	11793248
Evaluation of cytogenetic effects of isoproturon on the root meristem cells of Allium sativum.	2001-09	11723721
Effect of YM-40461, a novel surfactant secretagogue, on chronic obstructive pulmonary diseases and similar symptoms in guinea pigs.	2001-09	11642007
Transformation of the insecticide teflubenzuron by microorganisms.	2001-09	11599720
Organoclays for controlled release of the herbicide fenuron.	2001-09	11561405
Pharmacological and biochemical characterization of A3 adenosine receptors in Jurkat T cells.	2001-09	11522603
Effect of isoproturon pretreatment on the biochemical toxicodynamics of anilofos in male rats.	2001-08-28	11522367
Fluorosulfonyl- and bis-(beta-chloroethyl)amino-phenylamino functionalized pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine derivatives: irreversible antagonists at the human A3 adenosine receptor and molecular modeling studies.	2001-08-16	11495585
Mammalian sweet taste receptors.	2001-08-10	11509186
Effect of sludge-amendment or nutrient addition on the biodegradation of the herbicide isoproturon in soil.	2001-08	11482681
Peroxisome proliferator-activated receptor subtype-specific regulation of hepatic and peripheral gene expression in the Zucker diabetic fatty rat.	2001-08	11474486
Examining the role of cholecystokinin in appetitive learning in the infant rat.	2001-08	11457527
Cholecystokinin-8 (CCK-8) has no effect on heart rate in rats lacking CCK-A receptors.	2001-08	11457521
Photoaffinity labelling with the cytokinin agonist azido-CPPU of a 34 kDa peptide of the intracellular pathogenesis-related protein family in the moss Physcomitrella patens.	2001-07	11516147
Sorption behavior of metolachlor, isoproturon, and terbuthylazine in soils.	2001-07	11495018
Resistance to ACCase-inhibiting herbicides and isoproturon in UK populations of Lolium multiflorum: mechanisms of resistance and implications for control.	2001-07	11464789
Involvement of cytochrome P-450 enzyme activity in the selectivity and safening action of pyrazosulfuron-ethyl.	2001-03	11455659
Biodegradation of the phenylurea herbicide isoproturon and its metabolites in agricultural soils.	2001	11693297
The novel IMPDH inhibitor VX-497 prolongs skin graft survival and improves graft versus host disease in mice.	2001	11447770

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:13:21 GMT 2025` Edited by `admin` on `Mon Mar 31 21:13:21 GMT 2025`
Record UNII	862I85399W
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NSC-2781

Preferred Name

English

N-PHENYLUREA

Systematic Name

English

PHENYLUREA

Systematic Name

English

UREA, PHENYL-

Systematic Name

English

PHENYLCARBAMIDE

Common Name

English

UREA, N-PHENYL-

Systematic Name

English

MONOPHENYLUREA

Systematic Name

English

N-PHENYLUREA [MI]

Common Name

English

1-PHENYLUREA

Systematic Name

English

ETHYL 5-NITRO-1H-INDOLE-3-CARBOXYLATE

Systematic Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

620304