Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C19H25Cl2N3O3 |
| Molecular Weight | 414.326 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC(=O)N1CCN([C@H](CN2CCCC2)C1)C(=O)CC3=CC=C(Cl)C(Cl)=C3
InChI
InChIKey=HJUAKZYKCANOOZ-OAHLLOKOSA-N
InChI=1S/C19H25Cl2N3O3/c1-27-19(26)23-8-9-24(15(13-23)12-22-6-2-3-7-22)18(25)11-14-4-5-16(20)17(21)10-14/h4-5,10,15H,2-3,6-9,11-13H2,1H3/t15-/m1/s1
| Molecular Formula | C19H25Cl2N3O3 |
| Molecular Weight | 414.326 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
GR 89696 is a potent and selective kappa-OR agonist. The (-)-isomer, GR103545, is the active enantiomer of GR89696. In a first-in-human Positron Emission Tomography study, [11C]GR103545 was shown to be a promising agent, which can be used to image and quantify kappa-OR in humans with brain disorders. The ( )-isomer of GR 89696 is inactive.
CNS Activity
Originator
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 10:45:00 GMT 2023
by
admin
on
Sat Dec 16 10:45:00 GMT 2023
|
| Record UNII |
860VEX6583
|
| Record Status |
Validated (UNII)
|
| Record Version |
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-
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860VEX6583
Created by
admin on Sat Dec 16 10:45:00 GMT 2023 , Edited by admin on Sat Dec 16 10:45:00 GMT 2023
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6603856
Created by
admin on Sat Dec 16 10:45:00 GMT 2023 , Edited by admin on Sat Dec 16 10:45:00 GMT 2023
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126766-42-5
Created by
admin on Sat Dec 16 10:45:00 GMT 2023 , Edited by admin on Sat Dec 16 10:45:00 GMT 2023
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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RACEMATE -> ENANTIOMER |
